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ONTOLOGY REPORT - ANNOTATIONS

Term:mitochondrial DNA replication
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Accession:GO:0006264 term browser browse the term
Definition:The process in which new strands of DNA are synthesized in the mitochondrion.
Synonyms:exact_synonym: mtDNA replication;   replication of mitochondrial DNA
 related_synonym: mitochondrial DNA synthesis;   mtDNA synthesis
 only_in_taxon: NCBITaxon:2759 ! Eukaryota

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mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNA2 DNA replication helicase/nuclease 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:62,926,221...62,985,843
Ensembl chr 9:62,926,674...62,985,842 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 acts_upstream_of_or_within ISO (PMID:16327803) MGI PMID:16327803 NCBI chr 5:4,109,612...4,139,789 JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:4,109,577...4,137,926 JBrowse link
G MGME1 mitochondrial genome maintenance exonuclease 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:47,028,568...47,050,950
Ensembl chr 2:47,029,329...47,050,948 		JBrowse link
G POLG DNA polymerase gamma, catalytic subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15888483) InterPro
MGI
TreeGrafter		 PMID:15888483 GO_REF:0000002 GO_REF:0000118 NCBI chr29:7,864,319...7,881,577
Ensembl chr29:7,863,277...7,882,068 		JBrowse link
G POLG2 DNA polymerase gamma 2, accessory subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23197651) Ensembl
MGI
TreeGrafter		 PMID:23197651 GO_REF:0000107 GO_REF:0000118 NCBI chr16:56,773,867...56,794,571
Ensembl chr16:56,776,330...56,794,654 		JBrowse link
G PRIMPOL primase and DNA directed polymerase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:130,611,105...130,653,614
Ensembl chr 7:130,611,133...130,657,450 		JBrowse link
G RNASEH1 ribonuclease H1 acts_upstream_of_or_within ISO (PMID:12667461) MGI PMID:12667461 NCBI chr14:104,095,771...104,111,051
Ensembl chr14:104,095,795...104,114,987 		JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:62,606,112...62,649,979
Ensembl chr 1:62,604,486...62,650,200 		JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in
acts_upstream_of_or_within		 ISO (PMID:17486094) ComplexPortal
MGI		 PMID:17486094 NCBI chr 8:97,055,111...97,091,980 JBrowse link
G RRM2B ribonucleotide reductase regulatory TP53 inducible subunit M2B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 8:97,055,012...97,092,182 JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
G TEFM transcription elongation factor, mitochondrial NOT|involved_in ISO (PMID:21278163) UniProt PMID:21278163 NCBI chr16:25,601,744...25,609,071
Ensembl chr16:25,601,941...25,608,209 		JBrowse link
G TK2 thymidine kinase 2 acts_upstream_of_or_within ISO (PMID:18434326) MGI PMID:18434326 NCBI chr 5:52,202,040...52,272,428
Ensembl chr 5:52,204,605...52,243,017 		JBrowse link
G TWNK twinkle mtDNA helicase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:94,006,183...94,012,783
Ensembl chr 9:94,006,188...94,013,164 		JBrowse link
negative regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 ISO RGD PMID:23800874 RGD:11557986 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G LIG3 DNA ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,487,953...28,511,945
Ensembl chr16:28,490,434...28,511,130 		JBrowse link
positive regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENDOG endonuclease G involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,322,828...9,326,833
Ensembl chr12:9,322,892...9,326,549 		JBrowse link
G MTNAP1 mitochondrial nucleoid associated protein 1 involved_in ISO (MGI:7564184|PMID:37676315) UniProt PMID:37676315 MGI:7564184 NCBI chr16:48,388,665...48,404,425
Ensembl chr16:48,386,342...48,403,958 		JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:110,492,340...110,504,176
Ensembl chr21:110,492,377...110,504,177 		JBrowse link
regulation of mitochondrial DNA replication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G METTL4 methyltransferase 4, N6-adenosine involved_in ISO (PMID:32183942) UniProt PMID:32183942 NCBI chr18:61,767,806...61,834,994
Ensembl chr18:61,799,324...61,834,973 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16925
    metabolic process 10515
      macromolecule metabolic process 8484
        nucleic acid metabolic process 4699
          DNA metabolic process 906
            mitochondrial DNA metabolic process 30
              mitochondrial DNA replication 20
                DNA synthesis involved in mitochondrial DNA replication 0
                kinetoplast DNA replication 0
                negative regulation of mitochondrial DNA replication 2
                positive regulation of mitochondrial DNA replication 3
                regulation of mitochondrial DNA replication + 6
Path 2
Term Annotations click to browse term
  biological_process 16925
    metabolic process 10515
      primary metabolic process 9206
        nucleobase-containing compound metabolic process 5211
          nucleic acid metabolic process 4699
            DNA metabolic process 906
              DNA replication 264
                DNA-templated DNA replication 158
                  mitochondrial DNA replication 20
                    DNA synthesis involved in mitochondrial DNA replication 0
                    kinetoplast DNA replication 0
                    negative regulation of mitochondrial DNA replication 2
                    positive regulation of mitochondrial DNA replication 3
                    regulation of mitochondrial DNA replication + 6
paths to the root