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ONTOLOGY REPORT - ANNOTATIONS


Term:mitochondrial DNA metabolic process
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Accession:GO:0032042 term browser browse the term
Definition:The chemical reactions and pathways involving mitochondrial DNA.
Synonyms:exact_synonym: mitochondrial DNA metabolism;   mtDNA metabolic process;   mtDNA metabolism


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mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H acts_upstream_of_or_within ISO (MGI:6304909|PMID:30705315) RGD PMID:30705315 MGI:6304909 NCBI chr13:51,512,376...51,613,829 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (PMID:25378300) RGD PMID:25378300 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit acts_upstream_of_or_within ISO MGI:5470227 (MGI:5465384|PMID:23197651) RGD PMID:23197651 MGI:5465384 NCBI chr10:91,712,586...91,723,008 JBrowse link
G Sesn2 sestrin 2 acts_upstream_of_or_within ISO MGI:3587950 (MGI:5444071|PMID:22958918) RGD PMID:22958918 MGI:5444071 NCBI chr 5:144,702,287...144,721,241 JBrowse link
G Tk2 thymidine kinase 2 acts_upstream_of_or_within ISO MGI:3808750 (MGI:3807446|PMID:18467430) RGD PMID:18467430 MGI:3807446 NCBI chr19:708,859...731,786 JBrowse link
G Top3a DNA topoisomerase III alpha involved_in ISO (PMID:29290614) RGD PMID:29290614 NCBI chr10:45,419,219...45,457,356 JBrowse link
mitochondrial DNA repair term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chchd4 coiled-coil-helix-coiled-coil-helix domain containing 4 acts_upstream_of_or_within ISO (MGI:5516376|PMID:24101517) RGD PMID:24101517 MGI:5516376 NCBI chr 4:123,968,264...123,977,398 JBrowse link
G Dna2 DNA replication helicase/nuclease 2 involved_in ISO
IEA
(PMID:19487465)
GO_REF:0000107
RGD
Ensembl
PMID:19487465 GO_REF:0000107 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Lig3 DNA ligase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4943977|PMID:21390132), (MGI:4943978|PMID:21390131)
(PMID:21390132)
RGD PMID:21390131 PMID:21390132, PMID:21873635 MGI:4943977 MGI:4943978, RGD:13792537 NCBI chr10:67,717,796...67,741,141 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 acts_upstream_of_or_within ISO (PMID:25378300) RGD PMID:25378300 NCBI chr13:92,307,593...92,339,406 JBrowse link
G Primpol primase and DNA directed polymerase involved_in ISO (MGI:6393030|PMID:29073063) RGD PMID:29073063 MGI:6393030 NCBI chr16:45,681,252...45,715,758 JBrowse link
G Slc25a16 solute carrier family 25 member 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:25,661,158...25,717,558 JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO MGI:3528279 (MGI:5516376|PMID:24101517) RGD PMID:24101517 MGI:5516376 NCBI chr10:54,300,070...54,311,525 JBrowse link
negative regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin involved_in ISO (MGI:5463828|PMID:23150719) RGD PMID:23150719 MGI:5463828 NCBI chr10:44,588,621...44,607,808 JBrowse link
positive regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppargc1a PPARG coactivator 1 alpha involved_in ISO (MGI:5463828|PMID:23150719) RGD PMID:23150719 MGI:5463828 NCBI chr14:58,860,752...59,516,525 JBrowse link
regulation of mitochondrial DNA metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpv17 mitochondrial inner membrane protein MPV17 involved_in ISO
IEA
ISS
(PMID:26760297)
GO_REF:0000107
(MGI:5776643|PMID:26760297)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26760297 GO_REF:0000024 GO_REF:0000107 MGI:5776643 NCBI chr 6:25,221,668...25,236,241 JBrowse link
G Stox1 storkhead box 1 involved_in ISO (PMID:24738702) RGD PMID:24738702 NCBI chr20:30,598,656...30,666,371 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cellular metabolic process 10753
        cellular macromolecule metabolic process 8240
          DNA metabolic process 883
            mitochondrial DNA metabolic process 16
              DNA synthesis involved in mitochondrial DNA replication 0
              mitochondrial DNA catabolic process 0
              mitochondrial DNA repair 7
              mitochondrion DNA recombination 0
              negative regulation of mitochondrial DNA metabolic process 1
              positive regulation of mitochondrial DNA metabolic process 1
              regulation of mitochondrial DNA metabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18342
      cellular component organization or biogenesis 6723
        cellular component organization 6483
          organelle organization 4060
            mitochondrion organization 549
              mitochondrial genome maintenance 24
                mitochondrial DNA metabolic process 16
                  DNA synthesis involved in mitochondrial DNA replication 0
                  mitochondrial DNA catabolic process 0
                  mitochondrial DNA repair 7
                  mitochondrion DNA recombination 0
                  negative regulation of mitochondrial DNA metabolic process 1
                  positive regulation of mitochondrial DNA metabolic process 1
                  regulation of mitochondrial DNA metabolic process + 4
paths to the root