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ONTOLOGY REPORT - ANNOTATIONS

Term:osmosensor activity
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Accession:GO:0005034 term browser browse the term
Definition:Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.


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osmosensor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 enables ISO MGI:2667379 (PMID:11025659), (PMID:12777254) RGD PMID:11025659 PMID:12777254 NCBI chr12:47,599,161...47,638,143
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
osmolarity-sensing monoatomic cation channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel enables ISO
IEA		 (PMID:15548533)
GO_REF:0000107		 RGD
Ensembl		 PMID:15548533 GO_REF:0000107 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 enables IDA PMID:21084682 UniProt PMID:21084682 RGD:401966867 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Tmem63a transmembrane protein 63a enables ISO (PMID:27045885) RGD PMID:27045885 NCBI chr13:92,662,872...92,696,186
Ensembl chr13:92,663,968...92,696,183 		JBrowse link
G Tmem63b transmembrane protein 63B enables ISO (PMID:27045885), (PMID:31243992), (PMID:32375046) RGD PMID:27045885 PMID:31243992 PMID:32375046 NCBI chr 9:15,313,867...15,340,722
Ensembl chr 9:15,320,432...15,340,720 		JBrowse link
G Tmem63c transmembrane protein 63c enables ISS
ISO		 GO_REF:0000024
(PMID:27045885)		 UniProt
RGD		 PMID:27045885 GO_REF:0000024 NCBI chr 6:106,667,389...106,738,778
Ensembl chr 6:106,672,934...106,736,990 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21091
    molecular function regulator activity 2257
      molecular sensor activity 67
        osmosensor activity 7
          osmolarity-sensing monoatomic cation channel activity 6
Path 2
Term Annotations click to browse term
  molecular_function 21091
    molecular transducer activity 2665
      signaling receptor activity 2665
        transmembrane signaling receptor activity 2416
          osmosensor activity 7
            osmolarity-sensing monoatomic cation channel activity 6
paths to the root