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ONTOLOGY REPORT - ANNOTATIONS


Term:small molecule sensor activity
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Accession:GO:0140299 term browser browse the term
Definition:Binding to a small molecule and eliciting a change in the protein's activity in response to the intracellular level of that small molecule.
Synonyms:exact_synonym: small molecular sensor activity


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calcium ion sensor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efcab9 EF-hand calcium binding domain 9 ISO
IBA
(MGI:MGI:6316499|PMID:31056283)
PMID:21873635
RGD PMID:31056283, PMID:21873635 MGI:MGI:6316499, RGD:13792537 NCBI chr10:17,399,291...17,406,915
Ensembl chr10:17,407,979...17,415,251
JBrowse link
G Efhb EF hand domain family, member B ISO (PMID:30481768) RGD PMID:30481768 NCBI chr 9:47,988...120,800
Ensembl chr 9:47,724...120,799
JBrowse link
G Efhd1 EF-hand domain family, member D1 ISO
IBA
(PMID:26975899)
PMID:21873635
RGD PMID:26975899, PMID:21873635 RGD:13792537 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Syt1 synaptotagmin 1 ISO (MGI:MGI:5141208|PMID:21521611) RGD PMID:21521611 MGI:MGI:5141208 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
osmolarity-sensing cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmem63a transmembrane protein 63a ISO (MGI:MGI:6378787|PMID:27045885) RGD PMID:27045885 MGI:MGI:6378787 NCBI chr13:99,219,585...99,253,176
Ensembl chr13:99,220,510...99,253,316
JBrowse link
G Tmem63b transmembrane protein 63B ISO (MGI:MGI:6378298|PMID:31243992), (MGI:MGI:6378787|PMID:27045885) RGD PMID:27045885, PMID:31243992 MGI:MGI:6378298, MGI:MGI:6378787 NCBI chr 9:17,698,697...17,725,479
Ensembl chr 9:17,705,212...17,725,378
JBrowse link
G Tmem63c transmembrane protein 63c ISS
ISO
GO_REF:0000024
(MGI:MGI:6378787|PMID:27045885)
UniProt
RGD
PMID:27045885 GO_REF:0000024, MGI:MGI:6378787 NCBI chr 6:111,044,099...111,120,659
Ensembl chr 6:111,049,559...111,120,799
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 IDA RGD PMID:18279313 RGD:10047048 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
osmosensor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 ISO MGI:MGI:2667379 (MGI:MGI:1926591|PMID:11025659), (MGI:MGI:2667243|PMID:12777254) RGD PMID:11025659, PMID:12777254 MGI:MGI:1926591, MGI:MGI:2667243 NCBI chr12:47,698,915...47,737,902
Ensembl chr12:47,698,947...47,737,902
JBrowse link
oxygen sensor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egln2 egl-9 family hypoxia-inducible factor 2 ISO (PMID:11595184) RGD PMID:11595184 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  molecular_function 20467
    small molecule sensor activity 10
      cadmium ion sensor activity 0
      calcium ion sensor activity 4
      carbon monoxide sensor activity 0
      copper ion sensor activity 0
      iron sensor activity 0
      lipid sensor activity + 0
      nitric oxide sensor activity 0
      osmosensor activity + 5
      oxygen sensor activity 1
      peroxide sensor activity 0
      phosphorelay sensor kinase activity 0
      zinc ion sensor activity 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.