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ONTOLOGY REPORT - ANNOTATIONS

Term:phosphodiesterase I activity
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Accession:GO:0004528 term browser browse the term
Definition:Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
Synonyms:broad_synonym: phosphodiesterase activity
 related_synonym: 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity;   5'-NPDase activity;   5'-PDE activity;   5'-PDase activity;   5'-exonuclease activity;   5'-nucleotide phosphodiesterase activity;   5'-phosphodiesterase activity;   5'NPDE activity;   PDE I activity;   alkaline phosphodiesterase activity;   exonuclease I activity;   nucleotide pyrophosphatase/phosphodiesterase I activity;   oligonucleate 5'-nucleotidohydrolase activity;   orthophosphoric diester phosphohydrolase activity
 xref: EC:3.1.4.1;   MetaCyc:3.1.4.1-RXN


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phosphodiesterase I activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 enables IDA
ISO
ISS
IBA		 (PMID:27467858)
GO_REF:0000024
GO_REF:0000033
MGI:6402836 (PMID:15096095), (PMID:1647027), (PMID:24770645)		 RGD
UniProt
GO_Central		 PMID:1647027 PMID:15096095 PMID:24770645 PMID:27467858 PMID:17187902 GO_REF:0000024 GO_REF:0000033, RGD:13204714 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 enables IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:17307740 GO_REF:0000033, RGD:9685416 NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 enables TAS
ISS
ISO		 GO_REF:0000024
(PMID:11342463)		 UniProt
RGD		 PMID:11342463 PMID:9096610 GO_REF:0000024, RGD:1299489 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr 1:117,915,323...117,945,044
Ensembl chr 1:117,917,099...117,944,977 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21090
    catalytic activity 6125
      hydrolase activity 2608
        hydrolase activity, acting on ester bonds 823
          phosphoric ester hydrolase activity 372
            phosphoric diester hydrolase activity 91
              phosphodiesterase I activity 4
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