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ONTOLOGY REPORT - ANNOTATIONS

Term:follicular B cell differentiation
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Accession:GO:0002316 term browser browse the term
Definition:The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: follicular B lymphocyte differentiation
 related_synonym: follicular B cell development

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follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRF8 interferon regulatory factor 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,301,878...71,325,622
Ensembl chr 5:71,302,233...71,325,613 		JBrowse link
G MUC19 mucin 19, oligomeric acts_upstream_of_or_within ISO (PMID:37475871) MGI PMID:37475871 NCBI chr11:36,679,954...36,829,714 JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12928432) Ensembl
MGI		 PMID:12928432 GO_REF:0000107 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISO (PMID:31000603) ARUK-UCL PMID:31000603 NCBI chr 1:17,935,037...17,961,638
Ensembl chr 1:17,935,922...17,961,717 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19806
    immune system process 2668
      leukocyte activation 1031
        lymphocyte activation 845
          B cell activation 300
            B cell activation involved in immune response 102
              mature B cell differentiation involved in immune response 38
                follicular B cell differentiation 4
Path 2
Term Annotations click to browse term
  biological_process 19806
    cellular process 19328
      cellular developmental process 4575
        cell differentiation 4574
          cell development 3260
            hemopoiesis 1051
              leukocyte differentiation 683
                mononuclear cell differentiation 554
                  lymphocyte differentiation 453
                    B cell differentiation 159
                      mature B cell differentiation 48
                        mature B cell differentiation involved in immune response 38
                          follicular B cell differentiation 4
paths to the root