Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:B cell activation involved in immune response
go back to main search page
Accession:GO:0002312 term browser browse the term
Definition:The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:related_synonym: B lymphocyte activation during immune response;   B-cell activation during immune response



show annotations for term's descendants           Sort by:
 
B cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr183 G protein-coupled receptor 183 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:12932356) RGD PMID:12932356 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
B cell proliferation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:1856663|MGI:2153718|MGI:96561 (MGI:1927957|PMID:11120811), (MGI:76334|PMID:7671324), (MGI:82358|PMID:8806812) RGD PMID:7671324 PMID:8806812 PMID:11120811 MGI:1927957 MGI:76334 MGI:82358 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Cd180 CD180 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3581654 (MGI:1860539|PMID:10880523)
RGD PMID:10880523 PMID:21873635 MGI:1860539, RGD:13792537 NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936
JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518), (PMID:16672701) RGD PMID:1373518 PMID:16672701 NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
JBrowse link
G Gapt Grb2-binding adaptor protein, transmembrane involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3809581 (MGI:3804359|PMID:18559951)
RGD PMID:18559951 PMID:21873635 MGI:3804359, RGD:13792537 NCBI chr 2:41,927,533...41,932,120
Ensembl chr 2:41,927,532...41,932,093
JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO MGI:2679632 (MGI:2677607|PMID:14517301) RGD PMID:14517301 MGI:2677607 NCBI chr 9:3,292,564...3,477,009
Ensembl chr 9:3,292,695...3,477,009
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:1860539|PMID:10880523)
Ensembl
RGD
PMID:10880523 GO_REF:0000107 MGI:1860539 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in ISO UniProtKB:P17433 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2386100 (MGI:2679743|PMID:12928432)
Ensembl
RGD
PMID:12928432 GO_REF:0000107 MGI:2679743 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO UniProtKB:P23611 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO MGI:1857117|MGI:2683027 (MGI:3619310|PMID:14607964) RGD PMID:14607964 MGI:3619310 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) RGD PMID:15688343 MGI:3531365 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO
GO_REF:0000024
(MGI:5450752|PMID:23045607)
UniProt
RGD
PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO
GO_REF:0000024
(MGI:5450752|PMID:23045607)
UniProt
RGD
PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irf8 interferon regulatory factor 8 involved_in ISO UniProtKB:P17433 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within ISO MGI:4235940 (MGI:5547463|PMID:23997217) RGD PMID:23997217 MGI:5547463 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 involved_in ISO (MGI:5450752|PMID:23045607) RGD PMID:23045607 MGI:5450752 NCBI chr 8:51,521,813...51,548,819
Ensembl chr 8:51,474,015...51,548,819
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO UniProtKB:P23611 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase involved_in
acts_upstream_of_or_within
ISO (MGI:5004983|PMID:21518874)
(MGI:3761960|PMID:17713479)
RGD PMID:17713479 PMID:21518874 MGI:3761960 MGI:5004983 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Batf basic leucine zipper ATF-like transcription factor involved_in ISS
ISO
GO_REF:0000024
(MGI:4456325|PMID:20421391), (MGI:5004732|PMID:21572431)
UniProt
RGD
PMID:20421391 PMID:21572431 GO_REF:0000024 MGI:4456325 MGI:5004732 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051
JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISO
GO_REF:0000107
(MGI:3687427|PMID:7529792)
Ensembl
RGD
PMID:7529792 GO_REF:0000107 MGI:3687427 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO MGI:2183944 (MGI:3052883|PMID:15280420) RGD PMID:15280420 MGI:3052883 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Exo1 exonuclease 1 acts_upstream_of_or_within ISO MGI:2653925 (MGI:3028407|PMID:14716311) RGD PMID:14716311 MGI:3028407 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Exosc3 exosome component 3 involved_in ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc6 exosome component 6 involved_in ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Lig4 DNA ligase 4 acts_upstream_of_or_within ISO MGI:1857732 (MGI:3761960|PMID:17713479) RGD PMID:17713479 MGI:3761960 NCBI chr16:79,518,393...79,526,956
Ensembl chr16:79,518,312...79,527,040
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857946 (MGI:2662086|PMID:12743174)
Ensembl
RGD
PMID:12743174 GO_REF:0000107 MGI:2662086 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857940|MGI:2151801 (MGI:1342394|PMID:10430621), (MGI:2662086|PMID:12743174)
Ensembl
RGD
PMID:10430621 PMID:12743174 GO_REF:0000107 MGI:1342394 MGI:2662086 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:109352|MGI:3653701 (MGI:3641510|PMID:16618598), (MGI:3723381|PMID:17015724) RGD PMID:16618598 PMID:17015724 MGI:3641510 MGI:3723381 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Nbn nibrin involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3529405|PMID:15668383)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15668383 GO_REF:0000024 GO_REF:0000107 MGI:3529405 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Rnf168 ring finger protein 168 involved_in ISS
ISO
GO_REF:0000024
(MGI:4420833|PMID:20080757)
UniProt
RGD
PMID:20080757 GO_REF:0000024 MGI:4420833 NCBI chr11:68,486,313...68,508,296
Ensembl chr11:68,486,321...68,508,277
JBrowse link
G Rnf8 ring finger protein 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:4420833|PMID:20080757)
UniProt
RGD
PMID:20080757 GO_REF:0000024 MGI:4420833 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Swap70 switching B-cell complex subunit SWAP70 acts_upstream_of_or_within ISO (MGI:1270060|PMID:9642267) RGD PMID:9642267 MGI:1270060 NCBI chr 1:164,267,588...164,328,796
Ensembl chr 1:164,267,609...164,328,794
JBrowse link
G Ung uracil-DNA glycosylase acts_upstream_of_or_within ISO MGI:1343961 (MGI:3723381|PMID:17015724) RGD PMID:17015724 MGI:3723381 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 acts_upstream_of_or_within ISO MGI:1926771|MGI:3047571|MGI:3641440 (MGI:3761960|PMID:17713479) RGD PMID:17713479 MGI:3761960 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808
JBrowse link
isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr6 C-C motif chemokine receptor 6 involved_in ISO (MGI:5787846|PMID:27174992) RGD PMID:27174992 MGI:5787846 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
JBrowse link
isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:1861796 (MGI:85481|PMID:9009202) RGD PMID:9009202 MGI:85481 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) RGD PMID:15688343 MGI:3531365 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3044313|PMID:15146182), (MGI:3838059|PMID:19217325)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:15146182 PMID:19217325 GO_REF:0000024 GO_REF:0000107 MGI:3044313 MGI:3838059 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (MGI:5818419|PMID:25729399) RGD PMID:25729399 MGI:5818419 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525
JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in ISO (MGI:5818419|PMID:25729399) RGD PMID:25729399 MGI:5818419 NCBI chr  X:115,131,720...115,314,854
Ensembl chr  X:115,131,909...115,314,854
JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISS
ISO
GO_REF:0000024
(MGI:3838059|PMID:19217325)
UniProt
RGD
PMID:19217325 GO_REF:0000024 MGI:3838059 NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008
JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (MGI:3838059|PMID:19217325) RGD PMID:19217325 MGI:3838059 NCBI chr 7:110,310,810...110,328,653
Ensembl chr 7:110,310,812...110,328,653
JBrowse link
G Notch2 notch receptor 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3838059|PMID:19217325)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19217325 GO_REF:0000024 GO_REF:0000107 MGI:3838059 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:1860716|PMID:10881171)
UniProt
RGD
PMID:10881171 GO_REF:0000024 MGI:1860716 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr183 G protein-coupled receptor 183 involved_in ISO (MGI:4352759|PMID:19597478) RGD PMID:19597478 MGI:4352759 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G LOC688282 hypothetical protein LOC688282 involved_in ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407
JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066
JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) RGD PMID:10755614 MGI:2387354 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in ISO (MGI:6214451|PMID:26000965) RGD PMID:26000965 MGI:6214451 NCBI chr 8:107,111,010...107,117,073
Ensembl chr 8:107,111,012...107,116,782
JBrowse link
negative regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Da2-19 uncharacterized LOC302729 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr  X:44,820,693...44,837,935
Ensembl chr  X:44,820,820...44,837,934
JBrowse link
G Thoc1 THO complex 1 involved_in ISO
IEA
(MGI:5520039|PMID:22144908)
GO_REF:0000107
RGD
Ensembl
PMID:22144908 GO_REF:0000107 MGI:5520039 NCBI chr18:983,606...1,020,379
Ensembl chr18:983,824...1,019,114
JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:103034|MGI:2158438 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:2385534 (MGI:6407632|PMID:29259245) RGD PMID:29259245 MGI:6407632 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Itm2a integral membrane protein 2A acts_upstream_of_or_within ISO MGI:5645968 (MGI:5613782|PMID:24831988) RGD PMID:24831988 MGI:5613782 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363
JBrowse link
G Lgals1 galectin 1 acts_upstream_of_or_within ISO (MGI:5301217|PMID:21753146) RGD PMID:21753146 MGI:5301217 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lgals8 galectin 8 acts_upstream_of_or_within ISO (MGI:5301217|PMID:21753146) RGD PMID:21753146 MGI:5301217 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO MGI:2448069 (MGI:1888604|PMID:10926756) RGD PMID:10926756 MGI:1888604 NCBI chr 1:242,478,130...242,481,083
Ensembl chr 1:242,478,130...242,481,083
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3763508|PMID:12496423) RGD PMID:12496423 MGI:3763508 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr 5:59,573,849...59,579,065
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (MGI:5009766|PMID:21255825) RGD PMID:21255825 MGI:5009766 NCBI chr19:39,021,308...39,023,535
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
GO_REF:0000024
(MGI:6393148|PMID:31806351)
UniProt
RGD
PMID:31806351 GO_REF:0000024 MGI:6393148 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
GO_REF:0000024
(MGI:6370097|PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISS
ISO
GO_REF:0000024
(MGI:6370097|PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 MGI:6370097 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:4821506|PMID:20671152) RGD PMID:20671152 MGI:4821506 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
PMID:21873635
RGD PMID:29656893 PMID:21873635 RGD:13792537 NCBI chr 3:119,938,695...120,011,068
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:35,294,956...35,301,865
Ensembl chr 2:35,295,859...35,302,346
JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:26642240)
UniProt
RGD
PMID:26642240 GO_REF:0000024 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415)
RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 MGI:3041657 MGI:3046005 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (MGI:5462481|PMID:23241889) RGD PMID:23241889 MGI:5462481 NCBI chr14:76,833,194...76,911,304
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14988498)
AgBase
RGD
PMID:14988498 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnfsf13 TNF superfamily member 13 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:14988498)
MGI:3038886 (MGI:3037416|PMID:14988498)
RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (MGI:3777853|PMID:12023368) RGD PMID:12023368 MGI:3777853 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3037416|PMID:14988498)
RGD PMID:14988498 PMID:21873635 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (MGI:1345885|PMID:10490661) RGD PMID:10490661 MGI:1345885 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (MGI:5763555|PMID:25404367) RGD PMID:25404367 MGI:5763555 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Cd28 Cd28 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857150 (MGI:62368|PMID:7688139)
Ensembl
RGD
PMID:7688139 GO_REF:0000107 MGI:62368 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831)
RGD PMID:12882831 PMID:21873635 MGI:2670820, RGD:13792537 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (MGI:87443|PMID:1830926) RGD PMID:1830926 MGI:87443 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:2670820|PMID:12882831), (MGI:3037416|PMID:14988498)
RGD PMID:12882831 PMID:14988498 PMID:21873635 MGI:2670820 MGI:3037416, RGD:13792537 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:1342394|PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 MGI:1342394 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 1:181,622,708...181,624,996 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (MGI:5752090|PMID:26744420) RGD PMID:26744420 MGI:5752090 NCBI chr 4:7,524,887...7,576,663
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (MGI:1342394|PMID:10430621) RGD PMID:10430621 MGI:1342394 NCBI chr12:10,676,819...10,701,161
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (MGI:85031|PMID:9015183) RGD PMID:9015183 MGI:85031 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (MGI:2670820|PMID:12882831) RGD PMID:12882831 MGI:2670820 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO UniProtKB:P22301 (PMID:22962438) RGD PMID:22962438 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Xbp1 X-box binding protein 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:11460154)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within ISO MGI:4128102 (MGI:4887518|PMID:21211721) RGD PMID:21211721 MGI:4887518 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
JBrowse link
G Mir181b1 microRNA 181b-1 acts_upstream_of_or_within ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr13:49,485,688...49,485,797
Ensembl chr13:49,485,688...49,485,797
JBrowse link
G Mir181b2 microRNA 181b-2 acts_upstream_of_or_within ISO (MGI:3817382|PMID:18762567) RGD PMID:18762567 MGI:3817382 NCBI chr 3:22,616,948...22,617,035
Ensembl chr 3:22,616,948...22,617,035
JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in ISO (MGI:5004983|PMID:21518874) RGD PMID:21518874 MGI:5004983 NCBI chr10:63,103,920...63,140,780
Ensembl chr10:63,103,921...63,140,780
JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO MGI:3696705 (MGI:3695768|PMID:16275384) RGD PMID:16275384 MGI:3695768 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within ISO MGI:3525439 (MGI:1926579|PMID:11057672) RGD PMID:11057672 MGI:1926579 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO MGI:3695433 (MGI:3694584|PMID:17137798) RGD PMID:17137798 MGI:3694584 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311
JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5649169|PMID:25310967)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:25310967 GO_REF:0000024 GO_REF:0000107 MGI:5649169 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    immune system process 2885
      leukocyte activation 1086
        leukocyte activation involved in immune response 307
          lymphocyte activation involved in immune response 210
            B cell activation involved in immune response 93
              B cell proliferation involved in immune response 6
              isotype switching + 58
              mature B cell differentiation involved in immune response + 29
Path 2
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      cell activation 1230
        cell activation involved in immune response 311
          leukocyte activation involved in immune response 307
            lymphocyte activation involved in immune response 210
              B cell activation involved in immune response 93
                B cell proliferation involved in immune response 6
                isotype switching + 58
                mature B cell differentiation involved in immune response + 29
paths to the root