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ONTOLOGY REPORT - ANNOTATIONS

Term:mature B cell differentiation involved in immune response
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Accession:GO:0002313 term browser browse the term
Definition:The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:related_synonym: mature B cell development involved in immune response;   mature B-cell differentiation during immune response;   mature B-lymphocyte differentiation during immune response


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mature B cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C10h17orf99 smilar to human chromosome 17 open reading frame 99 involved_in ISO (MGI:6103709|PMID:28978694) RGD PMID:28978694 MGI:6103709 NCBI chr10:103,015,371...103,027,407
Ensembl chr10:103,016,505...103,027,407 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISO (MGI:4352759|PMID:19597478) RGD PMID:19597478 MGI:4352759 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:87,902,373...87,910,227
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
follicular B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Irf8 interferon regulatory factor 8 involved_in ISO UniProtKB:P17433 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386100 (PMID:12928432)		 Ensembl
RGD		 PMID:12928432 GO_REF:0000107 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO UniProtKB:P23611 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
germinal center B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964)		 Ensembl
RGD		 PMID:14607964 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) RGD PMID:15688343 MGI:3531365 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Il21 interleukin 21 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)		 UniProt
RGD		 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996 		JBrowse link
G Il6 interleukin 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5450752|PMID:23045607)		 UniProt
RGD		 PMID:23045607 GO_REF:0000024 MGI:5450752 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf8 interferon regulatory factor 8 involved_in ISO UniProtKB:P17433 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 acts_upstream_of_or_within ISO MGI:4235940 (PMID:23997217) RGD PMID:23997217 NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422 		JBrowse link
G Phf14 PHD finger protein 14 involved_in ISO (MGI:6514486|PMID:33035772) RGD PMID:33035772 MGI:6514486 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 involved_in ISO (MGI:5450752|PMID:23045607) RGD PMID:23045607 MGI:5450752 NCBI chr 8:51,521,813...51,548,819
Ensembl chr 8:51,474,015...51,548,819 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO UniProtKB:P23611 (MGI:6303891|PMID:31000603) RGD PMID:31000603 MGI:6303891 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
marginal zone B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:1861796 (PMID:9009202) RGD PMID:9009202 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Cdh17 cadherin 17 involved_in ISO (MGI:3531365|PMID:15688343) RGD PMID:15688343 MGI:3531365 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3044313|PMID:15146182), (MGI:3838059|PMID:19217325)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15146182 PMID:19217325 GO_REF:0000024 GO_REF:0000107 MGI:3044313 MGI:3838059 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (MGI:5818419|PMID:25729399) RGD PMID:25729399 MGI:5818419 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525 		JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in ISO
IBA		 (MGI:5818419|PMID:25729399)
GO_REF:0000033		 RGD
GO_Central		 PMID:25729399 GO_REF:0000033 MGI:5818419 NCBI chr  X:115,131,720...115,314,854
Ensembl chr  X:115,131,909...115,314,854 		JBrowse link
G Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:3838059|PMID:19217325)		 UniProt
Ensembl
RGD		 PMID:19217325 GO_REF:0000024 GO_REF:0000107 MGI:3838059 NCBI chr12:14,030,551...14,038,996
Ensembl chr12:14,018,333...14,039,008 		JBrowse link
G Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase involved_in ISO (MGI:3838059|PMID:19217325) RGD PMID:19217325 MGI:3838059 NCBI chr 7:110,310,810...110,328,653
Ensembl chr 7:110,310,812...110,328,653 		JBrowse link
G Notch2 notch receptor 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3838059|PMID:19217325)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19217325 GO_REF:0000024 GO_REF:0000107 MGI:3838059 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:1860716|PMID:10881171)		 UniProt
RGD		 PMID:10881171 GO_REF:0000024 MGI:1860716 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
memory B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) RGD PMID:10755614 MGI:2387354 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158439 (PMID:15240705) RGD PMID:15240705 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of ISO MGI:2158439 (PMID:15240705) RGD PMID:15240705 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:2385534 (PMID:29259245) RGD PMID:29259245 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Itm2a integral membrane protein 2A acts_upstream_of_or_within ISO MGI:5645968 (PMID:24831988) RGD PMID:24831988 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363 		JBrowse link
G Lgals1 galectin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21753146)		 Ensembl
RGD		 PMID:21753146 GO_REF:0000107 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lgals8 galectin 8 acts_upstream_of_or_within ISO (PMID:21753146) RGD PMID:21753146 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO MGI:5501251 (PMID:25124037) RGD PMID:25124037 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO MGI:2448069 (PMID:10926756) RGD PMID:10926756 NCBI chr 1:242,478,130...242,481,083
Ensembl chr 1:242,478,130...242,481,083 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO UniProtKB:P22301 (PMID:22962438) RGD PMID:22962438 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
ISS
IEA		 (PMID:11460154)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    immune system process 2982
      leukocyte activation 1048
        lymphocyte activation 847
          B cell activation 299
            B cell activation involved in immune response 95
              mature B cell differentiation involved in immune response 32
                follicular B cell differentiation 3
                germinal center B cell differentiation 9
                marginal zone B cell differentiation 9
                memory B cell differentiation 1
                plasma cell differentiation + 10
Path 2
Term Annotations click to browse term
  biological_process 20292
    cellular process 18769
      cellular developmental process 4747
        cell differentiation 4746
          cell development 3304
            hemopoiesis 1062
              leukocyte differentiation 674
                mononuclear cell differentiation 543
                  lymphocyte differentiation 447
                    B cell differentiation 161
                      mature B cell differentiation 41
                        mature B cell differentiation involved in immune response 32
                          follicular B cell differentiation 3
                          germinal center B cell differentiation 9
                          marginal zone B cell differentiation 9
                          memory B cell differentiation 1
                          plasma cell differentiation + 10
paths to the root