ONTOLOGY REPORT - ANNOTATIONS
Term: T-helper 1 cell lineage commitment
Accession: GO:0002296
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Definition: The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
Synonyms: exact_synonym: T-helper 1 cell fate commitment; Th1 cell lineage commitment; Th1 fate commitment
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IL4
interleukin 4
acts_upstream_of_or_within
ISO
(PMID:20706986)
MGI
PMID:20706986
NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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MTOR
mechanistic target of rapamycin kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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SPN
sialophorin
involved_in
IDA
(PMID:18036228)
UniProt
PMID:18036228
NCBI chr16:29,662,963...29,670,876
Ensembl chr16:29,662,979...29,670,876
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STAT6
signal transducer and activator of transcription 6
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:20706986)
Ensembl MGI
PMID:20706986
GO_REF:0000107
NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
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TBX21
T-box transcription factor 21
involved_in
IEA ISS
Ensembl UniProt
GO_REF:0000024 GO_REF:0000107
NCBI chr17:47,733,236...47,746,122
Ensembl chr17:47,733,236...47,746,122
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all