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ONTOLOGY REPORT - ANNOTATIONS

Term:mismatch base pair DNA N-glycosylase activity
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Accession:GO:0000700 term browser browse the term
Definition:Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.


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G/U mismatch-specific uracil-DNA glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tdg thymine-DNA glycosylase enables ISO (PMID:18512959) RGD PMID:18512959 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567 		JBrowse link
purine-specific mismatch base pair DNA N-glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mutyh mutY DNA glycosylase enables ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000003
(PMID:20848659)		 UniProt
GO_Central
RGD		 PMID:20848659 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:130,274,034...130,286,149
Ensembl chr 5:130,274,122...130,286,146 		JBrowse link
G Pcna proliferating cell nuclear antigen enables ISO (PMID:11005803) RGD PMID:11005803 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
pyrimidine-specific mismatch base pair DNA N-glycosylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase enables ISO (PMID:14614141) RGD PMID:14614141 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Tdg thymine-DNA glycosylase enables ISO
IBA		 (PMID:11889051), (PMID:18512959), (PMID:22573813), (PMID:8662714)
GO_REF:0000033		 RGD
GO_Central		 PMID:8662714 PMID:11889051 PMID:18512959 PMID:22573813 GO_REF:0000033 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on DNA 254
          DNA N-glycosylase activity 13
            mismatch base pair DNA N-glycosylase activity 4
              purine-specific mismatch base pair DNA N-glycosylase activity 2
              pyrimidine-specific mismatch base pair DNA N-glycosylase activity + 2
Path 2
Term Annotations click to browse term
  molecular_function 20483
    catalytic activity 6036
      hydrolase activity 2592
        hydrolase activity, acting on glycosyl bonds 134
          hydrolase activity, hydrolyzing N-glycosyl compounds 34
            DNA N-glycosylase activity 13
              mismatch base pair DNA N-glycosylase activity 4
                purine-specific mismatch base pair DNA N-glycosylase activity 2
                pyrimidine-specific mismatch base pair DNA N-glycosylase activity + 2
paths to the root