RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.
Synonyms:
exact_synonym:
Antidiuretic Hormone, Inappropriate Secretion; Inappropriate Vasopressin Secretion Syndrome; SIADH; Schwartz Bartter Syndrome; Syndrome of Inappropriate ADH (SIADH) Secretion; syndrome of Inappropriate Antidiuretic Hormone Secretion; syndrome of inappropriate secretion of ADH; syndrome of inappropriate secretion of antidiuretic hormone; syndrome of inappropriate vasopressin secretion