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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:aflatoxins-related hepatocellular carcinoma
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Accession:DOID:5022 term browser browse the term
Definition:A hepatocellular carcinoma that develops following exposure to aflatoxin.
Synonyms:xref: NCI:C27922
For additional species annotation, visit the Alliance of Genome Resources.


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aflatoxins-related hepatocellular carcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx1 epoxide hydrolase 1 IEP associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP associated with estrogen excess;protein:increased activity;liver (rat) RGD PMID:6133380 RGD:152998935 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18976
    disease of cellular proliferation 7746
      cancer 5576
        cell type cancer 3837
          carcinoma 3278
            adenocarcinoma 1713
              hepatocellular carcinoma 950
                aflatoxins-related hepatocellular carcinoma 2
Path 2
Term Annotations click to browse term
  disease 18976
    disease of cellular proliferation 7746
      Neoplasms by Site 7201
        Digestive System Neoplasms 3835
          Gastrointestinal Neoplasms 3710
            gastrointestinal system cancer 2908
              hepatobiliary system cancer 1104
                liver cancer 1015
                  liver carcinoma 955
                    hepatocellular carcinoma 950
                      aflatoxins-related hepatocellular carcinoma 2
paths to the root