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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:linitis plastica
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Accession:DOID:4023 term browser browse the term
Definition:A condition where the stomach wall becomes thickened, rubbery and loses its ability to distend. The stomach assumes a 'leather bottle' shape. It is most often seen in adenocarcinoma of the stomach. The term is often used synonymously with diffuse adenocarcinoma of the stomach.
Synonyms:exact_synonym: leather-bottle stomach
 primary_id: MESH:D008039
 xref: ICDO:8142/3;   NCI:C3190
For additional species annotation, visit the Alliance of Genome Resources.


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linitis plastica term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Psca prostate stem cell antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:18488030 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      Neoplasms by Histologic Type 5287
        Glandular and Epithelial Neoplasms 3739
          carcinoma 3202
            adenocarcinoma 1713
              scirrhous adenocarcinoma 1
                linitis plastica 1
Path 2
Term Annotations click to browse term
  disease 18969
    disease of anatomical entity 18249
      gastrointestinal system disease 7095
        Digestive System Neoplasms 3837
          Gastrointestinal Neoplasms 3712
            Stomach Neoplasms 567
              stomach cancer 301
                stomach carcinoma 116
                  gastric adenocarcinoma 87
                    gastric diffuse adenocarcinoma 1
                      linitis plastica 1
paths to the root