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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:netilmycin
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Accession:CHEBI:7528 term browser browse the term
Definition:A beta-L-arabinoside that has formula C21H41N5O7.
Synonyms:exact_synonym: (1S,2S,3R,4S,6R)-4-amino-3-[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yloxy]-6-(ethylamino)-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside
 related_synonym: 1-N-Ethylsisomicin;   Formula=C21H41N5O7;   InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)15(28)17(13)33-20-21(2,29)18(25-3)14(27)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15+,16-,17+,18-,19-,20-,21-/m1/s1;   InChIKey=ZBGPYVZLYBDXKO-HILBYHGXSA-N;   Netilmicin;   O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-N(1)-ethyl-D-streptamine;   SMILES=CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@H](O)[C@@H](NC)[C@@]1(C)O
 xref: CAS:56391-56-1;   DrugBank:DB00955;   KEGG:C07657;   KEGG:D08268
 xref_mesh: MESH:D009428



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netilmycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pgd phosphogluconate dehydrogenase decreases activity ISO Netilmicin results in decreased activity of PGD protein CTD PMID:15558954 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22210
    role 22195
      biological role 22194
        antimicrobial agent 19597
          carbohydrate-containing antibiotic 7436
            aminoglycoside antibiotic 7424
              netilmycin 1
                netilmicin sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22210
    subatomic particle 22202
      composite particle 22202
        hadron 22202
          baryon 22202
            nucleon 22202
              atomic nucleus 22202
                atom 22202
                  main group element atom 22136
                    p-block element atom 22136
                      carbon group element atom 21936
                        carbon atom 21861
                          organic molecular entity 21861
                            heteroorganic entity 21517
                              organochalcogen compound 21006
                                organooxygen compound 20847
                                  carbohydrates and carbohydrate derivatives 16048
                                    carbohydrate 16048
                                      carbohydrate derivative 14797
                                        glycosyl compound 13168
                                          glycoside 11881
                                            pentoside 588
                                              arabinoside 586
                                                beta-L-arabinoside 1
                                                  netilmycin 1
                                                    netilmicin sulfate 0
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