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ONTOLOGY REPORT - ANNOTATIONS


Term:posaconazole
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Accession:CHEBI:64355 term browser browse the term
Definition:An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.
Synonyms:exact_synonym: 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-4-({4-[4-(4-{1-[(2S,3S)-2-hydroxypentan-3-yl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenoxy}methyl)-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
 related_synonym: Formula=C37H42F2N8O4;   InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1;   InChIKey=RAGOYPUPXAKGKH-XAKZXMRKSA-N;   Noxafil;   SCH56592;   SMILES=CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O;   Sch 56592;   Schering 56592
 xref: CAS:171228-49-2 "ChemIDplus";   CAS:171228-49-2 "KEGG DRUG";   DrugBank:DB01263;   Drug_Central:3483 "DrugCentral";   KEGG:D02555
 xref_mesh: MESH:C101425
 xref: PMID:21762211 "Europe PMC";   PMID:21967490 "Europe PMC";   PMID:22058198 "Europe PMC";   PMID:22176629 "Europe PMC";   PMID:22215361 "Europe PMC";   PMID:22215487 "Europe PMC";   PMID:22286158 "Europe PMC";   PMID:22290952 "Europe PMC";   PMID:22303909 "Europe PMC";   PMID:22324990 "Europe PMC";   PMID:22330929 "Europe PMC";   PMID:22380765 "Europe PMC";   PMID:22391464 "Europe PMC";   PMID:22391534 "Europe PMC";   PMID:22427614 "Europe PMC";   Patent:US5661151;   Patent:WO9517407;   Reaxys:8379448 "Reaxys";   Wikipedia:Posaconazole


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posaconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        antimicrobial agent 17151
          antimicrobial drug 6008
            antiprotozoal drug 3670
              trypanocidal drug 74
                posaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  heteroarene 15146
                                    monocyclic heteroarene 11614
                                      azole 10473
                                        triazoles 3607
                                          triazole antifungal agent 2356
                                            triazole antifungal drug 57
                                              posaconazole 1
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