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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11b3
Name: cytochrome P450, family 11, subfamily b, polypeptide 3
Acc ID: CHEBI:64355
Term: posaconazole
Definition: An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug.
Chemical ID: MESH:C101425
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b3multiple interactionsISOCYP11B2 (Homo sapiens)6480464CTDposaconazole binds to and results in decreased activity of CYP11B2 proteinPMID:31982514
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