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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-valerolactone
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Accession:CHEBI:48569 term browser browse the term
Definition:A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a methyl group at position 5. It has been found in the urine samples of humans exposed to n-hexane.
Synonyms:exact_synonym: 5-methyldihydrofuran-2(3H)-one
 related_synonym: 4-Hydroxypentanoic acid lactone;   4-Hydroxyvaleric acid lactone;   4-Methyl-4-hydroxybutanoic acid lactone;   4-Methyl-gamma-butyrolactone;   4-Pentanolide;   4-Valerolactone;   Formula=C5H8O2;   InChI=1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3;   InChIKey=GAEKPEKOJKCEMS-UHFFFAOYSA-N;   SMILES=CC1CCC(=O)O1;   dihydro-5-methyl-2(3H)-furanone;   gamma-Pentalactone;   gamma-Pentanolactone
 xref: Beilstein:80420;   CAS:108-29-2;   HMDB:HMDB0033840
 xref_mesh: MESH:C037556
 xref: PMID:23486087;   PMID:7470400;   Patent:CN101633649;   Reaxys:80420;   Wikipedia:Gamma-Valerolactone


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gamma-valerolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity EXP gamma-valerolactone results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26050
    role 25966
      application 25188
        food additive 18342
          flavouring agent 4784
            gamma-valerolactone 1
              (R)-gamma-valerolactone 0
              (S)-gamma-valerolactone 0
              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26050
    subatomic particle 26025
      composite particle 26025
        hadron 26025
          baryon 26025
            nucleon 26025
              atomic nucleus 26025
                atom 26025
                  main group element atom 25850
                    p-block element atom 25850
                      carbon group element atom 25447
                        carbon atom 25405
                          organic molecular entity 25405
                            heteroorganic entity 24782
                              organochalcogen compound 24395
                                organooxygen compound 24072
                                  ester 18828
                                    carboxylic ester 17971
                                      lactone 13645
                                        gamma-lactone 6965
                                          butan-4-olide 309
                                            gamma-valerolactone 1
                                              (R)-gamma-valerolactone 0
                                              (S)-gamma-valerolactone 0
                                              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
                                              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
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