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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:m-Chlorophenylbiguanide
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Accession:CHEBI:32347 term browser browse the term
Definition:A biguanide that has formula C8H10ClN5.
Synonyms:related_synonym: Formula=C8H10ClN5;   InChI=1S/C8H10ClN5/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11/h1-4H,(H6,10,11,12,13,14);   InChIKey=DIHXJZHAIHGSAW-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)Nc1cccc(Cl)c1;   mCPBG
 xref: CAS:48144-44-1;   KEGG:C13646;   LINCS:LSM-2812
 xref_mesh: MESH:C065734


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m-Chlorophenylbiguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 1-(3-chlorophenyl)biguanide results in increased expression of FOS protein CTD PMID:12088752 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
decreases expression		 EXP BESEB CDRI-08 inhibits the reaction [1-(3-chlorophenyl)biguanide results in decreased expression of HTR3A mRNA] CTD PMID:21735137 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        pharmaceutical 19503
          drug 19471
            hypoglycemic agent 4201
              biguanides 445
                m-Chlorophenylbiguanide 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            organic molecule 19658
                              organic cyclic compound 19471
                                carbocyclic compound 18563
                                  benzenoid aromatic compound 17970
                                    benzenes 17830
                                      chlorobenzenes 14814
                                        monochlorobenzenes 11620
                                          m-Chlorophenylbiguanide 2
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