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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:biguanides
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Accession:CHEBI:53662 term browser browse the term
Definition:A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton.
Synonyms:alt_id: CHEBI:35529
 xref_mesh: MESH:D001645


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biguanides term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation EXP Biguanides results in increased phosphorylation of ACACA protein CTD PMID:22492524 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Cat catalase increases activity EXP Biguanides results in increased activity of CAT protein CTD PMID:18377884 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Gata5 GATA binding protein 5 affects expression ISO Biguanides analog affects the expression of GATA5 mRNA CTD PMID:17463086 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G H3f4 H3.4 histone affects methylation ISO Biguanides analog affects the methylation of H3-4 protein CTD PMID:17463086 NCBI chr10:45,304,696...45,305,106 JBrowse link
G Kdm1a lysine demethylase 1A decreases activity ISO Biguanides analog results in decreased activity of KDM1A protein CTD PMID:17463086 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation EXP Biguanides results in decreased phosphorylation of RPS6 protein CTD PMID:22492524 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 affects expression ISO Biguanides analog affects the expression of SFRP1 mRNA CTD PMID:17463086 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sfrp4 secreted frizzled-related protein 4 affects expression ISO Biguanides analog affects the expression of SFRP4 mRNA CTD PMID:17463086 NCBI chr17:47,383,983...47,394,065
Ensembl chr17:47,297,489...47,394,328
JBrowse link
G Sfrp5 secreted frizzled-related protein 5 affects expression ISO Biguanides analog affects the expression of SFRP5 mRNA CTD PMID:17463086 NCBI chr 1:261,442,108...261,446,570
Ensembl chr 1:261,442,108...261,446,570
JBrowse link
alexidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO alexidine results in decreased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO alexidine results in decreased expression of CCL3 protein CTD PMID:20116850 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO alexidine results in decreased expression of CCL4 protein CTD PMID:20116850 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO alexidine results in decreased expression of CCL5 protein CTD PMID:20116850 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO alexidine results in decreased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO alexidine results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO alexidine results in decreased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
chlorhexidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Chlorhexidine results in increased expression of HSPA5 protein CTD PMID:19027770 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chlorhexidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
chlorhexidine gluconate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase increases secretion EXP chlorhexidine gluconate results in increased secretion of GPT protein CTD PMID:145039 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
m-Chlorophenylbiguanide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 1-(3-chlorophenyl)biguanide results in increased expression of FOS protein CTD PMID:12088752 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
decreases expression
EXP BESEB CDRI-08 inhibits the reaction [1-(3-chlorophenyl)biguanide results in decreased expression of HTR3A mRNA] CTD PMID:21735137 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
phenformin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Phenformin results in decreased expression of A2M mRNA CTD PMID:31324951 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Phenformin results in increased expression of ABCB4 mRNA CTD PMID:31324951 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Phenformin results in increased expression of ABCC3 mRNA CTD PMID:31324951 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 increases expression EXP Phenformin results in increased expression of ABCD2 mRNA CTD PMID:31324951 NCBI chr 7:132,294,564...132,343,169
Ensembl chr 7:132,294,562...132,343,169
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression EXP Phenformin results in decreased expression of ABCG2 mRNA CTD PMID:31324951 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Phenformin results in increased expression of ABCG5 mRNA CTD PMID:31324951 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Phenformin results in increased expression of ABCG8 mRNA CTD PMID:31324951 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abra actin-binding Rho activating protein decreases expression EXP Phenformin results in decreased expression of ABRA mRNA CTD PMID:31324951 NCBI chr 7:80,792,615...80,796,683
Ensembl chr 7:80,792,600...80,796,670
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP Phenformin results in decreased expression of ACACA mRNA CTD PMID:31324951 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ackr3 atypical chemokine receptor 3 decreases expression EXP Phenformin results in decreased expression of ACKR3 mRNA CTD PMID:31324951 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Acly ATP citrate lyase decreases expression EXP Phenformin results in decreased expression of ACLY mRNA CTD PMID:31324951 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP Phenformin results in increased expression of ACMSD mRNA CTD PMID:31324951 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP Phenformin results in decreased expression of ACSL3 mRNA CTD PMID:31324951 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Phenformin results in decreased expression of ACTG1 mRNA CTD PMID:31324951 NCBI chr10:109,518,429...109,521,288
Ensembl chr 3:75,643,054...75,644,954
Ensembl chr10:75,643,054...75,644,954
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP Phenformin results in decreased expression of ADAMTS1 mRNA CTD PMID:31324951 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP Phenformin results in increased expression of ADH4 mRNA CTD PMID:31324951 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) increases expression EXP Phenformin results in increased expression of ADH6 mRNA CTD PMID:31324951 NCBI chr 2:243,656,568...243,687,857
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Afmid arylformamidase decreases expression EXP Phenformin results in decreased expression of AFMID mRNA CTD PMID:31324951 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP Phenformin results in increased expression of AGXT mRNA CTD PMID:31324951 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP Phenformin results in decreased expression of ALAS2 mRNA CTD PMID:31324951 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Phenformin results in increased expression of ALDH1A1 mRNA CTD PMID:31324951 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Phenformin results in decreased expression of ALOX15 mRNA CTD PMID:31324951 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Amacr alpha-methylacyl-CoA racemase increases expression EXP Phenformin results in increased expression of AMACR mRNA CTD PMID:31324951 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Amdhd1 amidohydrolase domain containing 1 increases expression EXP Phenformin results in increased expression of AMDHD1 mRNA CTD PMID:31324951 NCBI chr 7:34,362,635...34,406,282
Ensembl chr 7:34,361,633...34,406,318
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Phenformin affects the expression of ANGPTL4 mRNA CTD PMID:31324951 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Angptl8 angiopoietin-like 8 decreases expression EXP Phenformin results in decreased expression of ANGPTL8 mRNA CTD PMID:31324951 NCBI chr 8:22,855,495...22,858,565
Ensembl chr 8:22,856,539...22,858,565
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP Phenformin results in decreased expression of ANKH mRNA CTD PMID:31324951 NCBI chr 2:80,131,563...80,256,948
Ensembl chr 2:80,131,563...80,256,954
JBrowse link
G Anlnl1 anillin, actin binding protein-like 1 decreases expression EXP Phenformin results in decreased expression of ANLNL1 mRNA CTD PMID:31324951 NCBI chr17:66,542,420...66,553,118
Ensembl chr17:66,548,818...66,551,947
JBrowse link
G Ano5 anoctamin 5 decreases expression EXP Phenformin results in decreased expression of ANO5 mRNA CTD PMID:31324951 NCBI chr 1:106,873,580...106,971,769
Ensembl chr 1:106,896,790...106,968,885
JBrowse link
G Apcdd1 APC down-regulated 1 increases expression EXP Phenformin results in increased expression of APCDD1 mRNA CTD PMID:31324951 NCBI chr18:58,270,398...58,300,982
Ensembl chr18:58,270,410...58,301,002
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit decreases expression EXP Phenformin results in decreased expression of APH1B mRNA CTD PMID:31324951 NCBI chr 8:72,508,008...72,598,921
Ensembl chr 8:72,476,425...72,629,265
JBrowse link
G Aplnr apelin receptor increases expression EXP Phenformin results in increased expression of APLNR mRNA CTD PMID:31324951 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP Phenformin results in decreased expression of APOA4 mRNA CTD PMID:31324951 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoc4 apolipoprotein C4 increases expression EXP Phenformin results in increased expression of APOC4 mRNA CTD PMID:31324951 NCBI chr 1:80,595,339...80,599,525
Ensembl chr 1:80,595,326...80,599,572
JBrowse link
G Apof apolipoprotein F increases expression EXP Phenformin results in increased expression of APOF mRNA CTD PMID:31324951 NCBI chr 7:2,689,501...2,690,938
Ensembl chr 7:2,689,501...2,690,936
JBrowse link
G Apold1 apolipoprotein L domain containing 1 decreases expression EXP Phenformin results in decreased expression of APOLD1 mRNA CTD PMID:31324951 NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Phenformin results in increased expression of AQP7 mRNA CTD PMID:31324951 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Phenformin results in increased expression of AQP9 mRNA CTD PMID:31324951 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Ar androgen receptor decreases expression EXP Phenformin results in decreased expression of AR mRNA CTD PMID:31324951 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression EXP Phenformin results in decreased expression of ARHGAP11A mRNA CTD PMID:31324951 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression EXP Phenformin results in increased expression of ARRDC4 mRNA CTD PMID:31324951 NCBI chr 1:129,766,097...129,780,076
Ensembl chr 1:129,766,100...129,780,356
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Phenformin results in increased expression of ASL mRNA CTD PMID:31324951 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression EXP Phenformin results in decreased expression of ASPM mRNA CTD PMID:31324951 NCBI chr13:56,546,021...56,591,793
Ensembl chr13:56,546,021...56,591,793
JBrowse link
G Aspn asporin decreases expression EXP Phenformin results in decreased expression of ASPN mRNA CTD PMID:31324951 NCBI chr17:14,655,958...14,681,355
Ensembl chr17:14,656,009...14,679,409
JBrowse link
G Atf3 activating transcription factor 3 decreases expression EXP Phenformin results in decreased expression of ATF3 mRNA CTD PMID:31324951 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Aurkb aurora kinase B decreases expression EXP Phenformin results in decreased expression of AURKB mRNA CTD PMID:31324951 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Bex1 brain expressed, X-linked 1 increases expression EXP Phenformin results in increased expression of BEX1 mRNA CTD PMID:31324951 NCBI chr  X:106,761,388...106,771,656 JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP Phenformin results in decreased expression of BHLHE40 mRNA CTD PMID:31324951 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP Phenformin results in decreased expression of BTG2 mRNA CTD PMID:31324951 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression EXP Phenformin results in decreased expression of BUB1 mRNA CTD PMID:31324951 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Ca5a carbonic anhydrase 5A increases expression EXP Phenformin results in increased expression of CAR5A mRNA CTD PMID:31324951 NCBI chr19:54,731,829...54,761,697
Ensembl chr19:54,731,859...54,761,670
JBrowse link
G Ca5b carbonic anhydrase 5B decreases expression EXP Phenformin results in decreased expression of CAR5B mRNA CTD PMID:31324951 NCBI chr  X:32,232,106...32,291,124
Ensembl chr  X:32,232,142...32,292,072
JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases expression EXP Phenformin results in decreased expression of CCDC141 mRNA CTD PMID:31324951 NCBI chr 3:63,865,240...64,024,208
Ensembl chr 3:63,863,951...64,024,205
JBrowse link
G Ccdc38 coiled-coil domain containing 38 increases expression EXP Phenformin results in increased expression of CCDC38 mRNA CTD PMID:31324951 NCBI chr 7:34,402,861...34,477,750
Ensembl chr 7:34,402,738...34,477,932
JBrowse link
G Ccdc77 coiled-coil domain containing 77 increases expression EXP Phenformin results in increased expression of CCDC77 mRNA CTD PMID:31324951 NCBI chr 4:152,860,669...152,892,518
Ensembl chr 4:152,860,675...152,883,210
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Phenformin results in decreased expression of CCL2 mRNA CTD PMID:31324951 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP Phenformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Phenformin results in decreased expression of CCNA2 mRNA CTD PMID:31324951 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Phenformin results in decreased expression of CCNB1 mRNA CTD PMID:31324951 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 affects expression EXP Phenformin affects the expression of CCNB2 mRNA CTD PMID:31324951 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Phenformin results in increased expression of CCND1 mRNA CTD PMID:31324951 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Phenformin results in decreased expression of CCNE2 mRNA CTD PMID:31324951 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd226 CD226 molecule decreases expression EXP Phenformin results in decreased expression of CD226 mRNA CTD PMID:31324951 NCBI chr18:86,299,392...86,394,772
Ensembl chr18:86,299,463...86,394,765
JBrowse link
G Cd274 CD274 molecule increases expression EXP Phenformin results in increased expression of CD274 mRNA CTD PMID:31324951 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd5l Cd5 molecule-like increases expression EXP Phenformin results in increased expression of CD5L mRNA CTD PMID:31324951 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd63 Cd63 molecule increases expression EXP Phenformin results in increased expression of CD63 mRNA CTD PMID:31324951 NCBI chr 7:3,320,250...3,335,583
Ensembl chr 7:3,320,103...3,335,582
JBrowse link
G Cd74 CD74 molecule increases expression EXP Phenformin results in increased expression of CD74 mRNA CTD PMID:31324951 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP Phenformin results in decreased expression of CDC20 mRNA CTD PMID:31324951 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Phenformin results in decreased expression of CDK1 mRNA CTD PMID:31324951 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO
EXP
Phenformin results in increased expression of CDKN1A protein
Phenformin results in decreased expression of CDKN1A mRNA
CTD PMID:14623034 PMID:31324951 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Phenformin results in decreased expression of CDKN3 mRNA CTD PMID:31324951 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression EXP Phenformin results in decreased expression of TMEM2 mRNA CTD PMID:31324951 NCBI chr 1:239,397,322...239,474,931
Ensembl chr 1:239,398,043...239,474,931
JBrowse link
G Cenpe centromere protein E decreases expression EXP Phenformin results in decreased expression of CENPE mRNA CTD PMID:31324951 NCBI chr 2:240,395,974...240,454,785
Ensembl chr 2:240,396,152...240,454,747
JBrowse link
G Cenpf centromere protein F decreases expression EXP Phenformin results in decreased expression of CENPF mRNA CTD PMID:31324951 NCBI chr13:108,132,499...108,178,609
Ensembl chr13:108,132,499...108,178,609
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP Phenformin results in increased expression of CES2C mRNA CTD PMID:31324951 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Ces4a carboxylesterase 4A decreases expression EXP Phenformin results in decreased expression of CES4A mRNA CTD PMID:31324951 NCBI chr19:37,090,018...37,111,448
Ensembl chr19:37,090,056...37,107,872
JBrowse link
G Chka choline kinase alpha decreases expression EXP Phenformin results in decreased expression of CHKA mRNA CTD PMID:31324951 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression EXP Phenformin results in decreased expression of CISH mRNA CTD PMID:31324951 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression EXP Phenformin results in decreased expression of CKAP2 mRNA CTD PMID:31324951 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP Phenformin results in decreased expression of CKS2 mRNA CTD PMID:31324951 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clec1a C-type lectin domain family 1, member A decreases expression EXP Phenformin results in decreased expression of CLEC1A mRNA CTD PMID:31324951 NCBI chr 4:163,191,503...163,214,678
Ensembl chr 4:163,191,503...163,214,678
JBrowse link
G Clec1b C-type lectin domain family 1, member B decreases expression EXP Phenformin results in decreased expression of CLEC1B mRNA CTD PMID:31324951 NCBI chr 4:163,161,941...163,170,470
Ensembl chr 4:163,162,211...163,170,466
JBrowse link
G Cpne8 copine 8 increases expression EXP Phenformin results in increased expression of CPNE8 mRNA CTD PMID:31324951 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Phenformin results in increased expression of CPT1A mRNA CTD PMID:31324951 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP Phenformin results in increased expression of CRAT mRNA CTD PMID:31324951 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP Phenformin results in increased expression of CROT mRNA CTD PMID:31324951 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of CRY1 mRNA CTD PMID:31324951 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP Phenformin results in increased expression of CRYL1 mRNA CTD PMID:31324951 NCBI chr15:37,543,727...37,663,586
Ensembl chr15:37,543,727...37,663,584
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP Phenformin results in decreased expression of CSAD mRNA CTD PMID:31324951 NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP Phenformin results in decreased expression of CSRP1 mRNA CTD PMID:31324951 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Phenformin results in decreased expression of CXCL1 mRNA CTD PMID:31324951 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Phenformin results in decreased expression of CXCL10 mRNA CTD PMID:31324951 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Phenformin results in increased expression of CXCR4 mRNA CTD PMID:31324951 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Phenformin results in decreased expression of CYP17A1 mRNA CTD PMID:31324951 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2B1 mRNA CTD PMID:31324951 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP Phenformin results in decreased expression of CYP2C12 mRNA CTD PMID:31324951 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression EXP Phenformin results in increased expression of CYP2C24 mRNA CTD PMID:31324951 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2E1 mRNA CTD PMID:31324951 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP Phenformin results in increased expression of CYP3A18 mRNA CTD PMID:31324951 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP4A1 mRNA CTD PMID:31324951 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Phenformin results in increased expression of CYP4A2 mRNA CTD PMID:31324951 NCBI chr 5:134,196,910...134,207,888
Ensembl chr 5:134,196,912...134,207,863
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP Phenformin results in decreased expression of CYP7A1 mRNA CTD PMID:31324951 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP Phenformin results in increased expression of CYP8B1 mRNA CTD PMID:31324951 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP Phenformin results in increased expression of DBP mRNA CTD PMID:31324951 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Dcn decorin decreases expression EXP Phenformin results in decreased expression of DCN mRNA CTD PMID:31324951 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Ddhd1 DDHD domain containing 1 increases expression EXP Phenformin results in increased expression of DDHD1 mRNA CTD PMID:31324951 NCBI chr15:19,963,639...20,032,263
Ensembl chr15:19,965,187...20,032,191
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression EXP Phenformin results in decreased expression of DDIT4 mRNA CTD PMID:31324951 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP Phenformin results in increased expression of DECR1 mRNA CTD PMID:31324951 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression EXP Phenformin results in decreased expression of DEPDC1 mRNA CTD PMID:31324951 NCBI chr 2:264,704,738...264,738,265
Ensembl chr 2:264,704,769...264,738,257
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression EXP Phenformin results in decreased expression of DIAPH3 mRNA CTD PMID:31324951 NCBI chr15:69,928,507...70,400,077
Ensembl chr15:70,039,424...70,399,924
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP Phenformin results in decreased expression of DIO1 mRNA CTD PMID:31324951 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP Phenformin results in increased expression of DMBT1 mRNA CTD PMID:31324951 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dmxl2 Dmx-like 2 decreases expression EXP Phenformin results in decreased expression of DMXL2 mRNA CTD PMID:31324951 NCBI chr 8:58,932,575...59,077,788
Ensembl chr 8:58,932,580...59,077,690
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Phenformin results in decreased expression of DUSP1 mRNA CTD PMID:31324951 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Phenformin results in increased expression of ECH1 mRNA CTD PMID:31324951 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP Phenformin results in increased expression of ECI1 mRNA CTD PMID:31324951 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression EXP Phenformin results in decreased expression of ECT2 mRNA CTD PMID:31324951 NCBI chr 2:112,769,385...112,831,476
Ensembl chr 2:112,769,385...112,831,476
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression EXP Phenformin results in decreased expression of EDEM1 mRNA CTD PMID:31324951 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 decreases expression EXP Phenformin results in decreased expression of EDIL3 mRNA CTD PMID:31324951 NCBI chr 2:17,616,116...18,128,514
Ensembl chr 2:17,616,401...18,128,512
JBrowse link
G Egr1 early growth response 1 decreases expression EXP Phenformin results in decreased expression of EGR1 mRNA CTD PMID:31324951 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression EXP Phenformin results in decreased expression of ELL2 mRNA CTD PMID:31324951 NCBI chr 2:2,456,189...2,525,590
Ensembl chr 2:2,456,735...2,524,237
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression EXP Phenformin results in increased expression of ELOVL2 mRNA CTD PMID:31324951 NCBI chr17:21,382,461...21,422,413
Ensembl chr17:21,382,455...21,422,407
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP Phenformin results in decreased expression of ELOVL6 mRNA CTD PMID:31324951 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Erich5 glutamate-rich 5 decreases expression EXP Phenformin results in decreased expression of ERICH5 mRNA CTD PMID:31324951 NCBI chr 7:73,222,331...73,243,684
Ensembl chr 7:73,222,730...73,242,899
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Phenformin results in decreased expression of ERRFI1 mRNA CTD PMID:31324951 NCBI chr 5:167,951,564...167,966,011
Ensembl chr 5:167,952,728...167,966,009
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression EXP Phenformin results in decreased expression of ESCO2 mRNA CTD PMID:31324951 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Phenformin results in increased expression of ESM1 mRNA CTD PMID:31324951 NCBI chr 2:45,104,392...45,113,130
Ensembl chr 2:45,104,305...45,113,131
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression EXP Phenformin results in decreased expression of F2RL2 mRNA CTD PMID:31324951 NCBI chr 2:26,240,385...26,245,533
Ensembl chr 2:26,240,385...26,245,533
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP Phenformin results in decreased expression of F3 mRNA CTD PMID:31324951 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP Phenformin results in decreased expression of FABP5 mRNA CTD PMID:31324951 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fam111a FAM111 trypsin like peptidase A decreases expression EXP Phenformin results in decreased expression of FAM111A mRNA CTD PMID:31324951 NCBI chr 1:229,003,778...229,019,532
Ensembl chr 1:229,003,961...229,019,527
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression EXP Phenformin results in increased expression of FAM117B mRNA CTD PMID:31324951 NCBI chr 9:66,716,969...66,784,487
Ensembl chr 9:66,716,969...66,784,487
JBrowse link
G Fam149a family with sequence similarity 149, member A decreases expression EXP Phenformin results in decreased expression of FAM149A mRNA CTD PMID:31324951 NCBI chr16:50,049,816...50,105,962
Ensembl chr16:50,049,828...50,107,856
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression EXP Phenformin results in decreased expression of FAM83D mRNA CTD PMID:31324951 NCBI chr 3:155,269,344...155,288,612
Ensembl chr 3:155,269,347...155,288,533
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Phenformin results in decreased expression of FASN mRNA CTD PMID:31324951 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression EXP Phenformin results in decreased expression of FMO2 mRNA CTD PMID:31324951 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP Phenformin results in increased expression of FMO5 mRNA CTD PMID:31324951 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of FOS mRNA CTD PMID:31324951 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa1 forkhead box A1 decreases expression EXP Phenformin results in decreased expression of FOXA1 mRNA CTD PMID:31324951 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP Phenformin results in decreased expression of FOXA2 mRNA CTD PMID:31324951 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxo3 forkhead box O3 decreases expression EXP Phenformin results in decreased expression of FOXO3 mRNA CTD PMID:31324951 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression EXP Phenformin results in decreased expression of FPR1 mRNA CTD PMID:31324951 NCBI chr 1:59,759,025...59,767,258
Ensembl chr 1:59,765,835...59,767,042
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 decreases expression EXP Phenformin results in decreased expression of FRAS1 mRNA CTD PMID:31324951 NCBI chr14:14,438,392...14,853,016
Ensembl chr14:14,439,082...14,689,554
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Phenformin results in decreased expression of G6PC mRNA CTD PMID:31324951 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP Phenformin results in decreased expression of GADD45G mRNA CTD PMID:31324951 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression EXP Phenformin results in decreased expression of GBE1 mRNA CTD PMID:31324951 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression EXP Phenformin results in increased expression of GBP1 mRNA CTD PMID:31324951 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gck glucokinase decreases expression EXP Phenformin results in decreased expression of GCK mRNA CTD PMID:31324951 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 decreases expression EXP Phenformin results in decreased expression of GIMD1 mRNA CTD PMID:31324951 NCBI chr 2:237,679,672...237,714,434
Ensembl chr 2:237,679,792...237,714,428
JBrowse link
G Gk glycerol kinase increases expression EXP Phenformin results in increased expression of GK mRNA CTD PMID:31324951 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Gnmt glycine N-methyltransferase increases expression EXP Phenformin results in increased expression of GNMT mRNA CTD PMID:31324951 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Phenformin results in increased expression of GOT1 mRNA CTD PMID:31324951 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gp5 glycoprotein V (platelet) decreases expression EXP Phenformin results in decreased expression of GP5 mRNA CTD PMID:31324951 NCBI chr11:73,015,380...73,017,570 JBrowse link
G Gpa33 glycoprotein A33 increases expression EXP Phenformin results in increased expression of GPA33 mRNA CTD PMID:31324951 NCBI chr13:84,334,598...84,368,154
Ensembl chr13:84,334,598...84,368,154
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Phenformin results in increased expression of GPAM mRNA CTD PMID:31324951 NCBI chr 1:275,843,823...275,906,880
Ensembl chr 1:275,846,819...275,906,686
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression EXP Phenformin results in increased expression of GPAT3 mRNA CTD PMID:31324951 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression EXP Phenformin results in increased expression of GPD2 mRNA CTD PMID:31324951 NCBI chr 3:43,223,892...43,359,069
Ensembl chr 3:43,255,567...43,359,074
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Phenformin results in increased expression of GPNMB mRNA CTD PMID:31324951 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gprin3 GPRIN family member 3 decreases expression EXP Phenformin results in decreased expression of GPRIN3 mRNA CTD PMID:31324951 NCBI chr 4:89,690,678...89,778,302
Ensembl chr 4:89,693,280...89,695,928
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Phenformin results in increased expression of GPT mRNA CTD PMID:31324951 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx2-ps2 glutathione peroxidase 2, pseudogene 2 affects expression EXP Phenformin affects the expression of GPX2-PS2 mRNA CTD PMID:31324951 NCBI chr  X:63,820,786...63,824,748 JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Phenformin results in increased expression of GSTM2 mRNA CTD PMID:31324951 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression EXP Phenformin results in increased expression of GSTM4 mRNA CTD PMID:31324951 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 increases expression EXP Phenformin results in increased expression of GSTM7 mRNA CTD PMID:31324951 NCBI chr 2:210,720,719...210,726,179
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression EXP Phenformin results in increased expression of GSTZ1 mRNA CTD PMID:31324951 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP Phenformin results in decreased expression of HAMP mRNA CTD PMID:31324951 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Phenformin results in decreased expression of HBB-B1 mRNA CTD PMID:31324951 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbb-bs hemoglobin, beta adult s chain decreases expression EXP Phenformin results in decreased expression of HBB-BS mRNA CTD PMID:31324951 NCBI chr 1:168,964,202...168,965,568
Ensembl chr 1:168,945,449...168,965,566
JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP Phenformin results in decreased expression of HHEX mRNA CTD PMID:31324951 NCBI chr 1:256,101,994...256,107,581
Ensembl chr 1:256,101,903...256,107,649
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Phenformin results in increased expression of HIF1A protein CTD PMID:26768367 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression EXP Phenformin results in decreased expression of HIST1H2AF mRNA CTD PMID:31324951 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression EXP Phenformin results in decreased expression of HIST1H2AIL1 mRNA CTD PMID:31324951 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
JBrowse link
G Hist1h2ak histone cluster 1, H2ak decreases expression EXP Phenformin results in decreased expression of HIST1H2AK mRNA CTD PMID:31324951 NCBI chr17:44,840,990...44,841,382
Ensembl chr17:44,840,990...44,841,382
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 decreases expression EXP Phenformin results in decreased expression of HIST2H3C2 mRNA CTD PMID:31324951 NCBI chr 2:198,390,024...198,418,075
Ensembl chr 2:198,417,619...198,418,029
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression EXP Phenformin results in decreased expression of HLF mRNA CTD PMID:31324951 NCBI chr10:77,836,352...77,918,656
Ensembl chr10:77,840,568...77,918,191
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP Phenformin results in decreased expression of HMGCR mRNA CTD PMID:31324951 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression EXP Phenformin results in decreased expression of HMMR mRNA CTD PMID:31324951 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression EXP Phenformin results in increased expression of HSD17B2 mRNA CTD PMID:31324951 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Phenformin results in decreased expression of HSP90AA1 mRNA CTD PMID:31324951 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like decreases expression EXP Phenformin results in decreased expression of HSPA4L mRNA CTD PMID:31324951 NCBI chr 2:127,625,737...127,682,864
Ensembl chr 2:127,625,683...127,677,503
JBrowse link
G Hykk hydroxylysine kinase increases expression EXP Phenformin results in increased expression of HYKK mRNA CTD PMID:31324951 NCBI chr 8:59,507,975...59,531,745
Ensembl chr 8:59,507,990...59,529,366
JBrowse link
G Ier2 immediate early response 2 decreases expression EXP Phenformin results in decreased expression of IER2 mRNA CTD PMID:31324951 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP Phenformin results in increased expression of IFITM3 mRNA CTD PMID:31324951 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression EXP Phenformin results in decreased expression of IGF2BP3 mRNA CTD PMID:31324951 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP Phenformin results in decreased expression of IGFALS mRNA CTD PMID:31324951 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP Phenformin results in increased expression of IGFBP2 mRNA CTD PMID:31324951 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Phenformin results in decreased expression of IGFBP5 mRNA CTD PMID:31324951 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP Phenformin results in increased expression of IL1R1 mRNA CTD PMID:31324951 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il33 interleukin 33 increases expression EXP Phenformin results in increased expression of IL33 mRNA CTD PMID:31324951 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Phenformin results in decreased expression of INHA mRNA CTD PMID:31324951 NCBI chr 9:82,700,482...82,703,383
Ensembl chr 9:82,700,468...82,703,400
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP Phenformin results in decreased expression of INHBA mRNA CTD PMID:31324951 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Inhbe inhibin subunit beta E increases expression EXP Phenformin results in increased expression of INHBE mRNA CTD PMID:31324951 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Phenformin results in increased expression of INMT mRNA CTD PMID:31324951 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP Phenformin results in decreased expression of INSIG1 mRNA CTD PMID:31324951 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Phenformin results in increased expression of INSIG2 mRNA CTD PMID:31324951 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 decreases expression EXP Phenformin results in decreased expression of IP6K2 mRNA CTD PMID:31324951 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression EXP Phenformin results in decreased expression of IRF2BP2 mRNA CTD PMID:31324951 NCBI chr19:59,497,021...59,502,298
Ensembl chr19:59,499,876...59,502,161
JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like decreases expression EXP Phenformin results in decreased expression of IRF2BPL mRNA CTD PMID:31324951 NCBI chr 6:110,901,940...110,904,288
Ensembl chr 6:110,901,940...110,904,288
JBrowse link
G Irs2 insulin receptor substrate 2 decreases expression EXP Phenformin results in decreased expression of IRS2 mRNA CTD PMID:31324951 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUN mRNA CTD PMID:31324951 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUNB mRNA CTD PMID:31324951 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 increases expression EXP Phenformin results in increased expression of KCNA2 mRNA CTD PMID:31324951 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Phenformin results in increased expression of KCNJ5 mRNA CTD PMID:31324951 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kif11 kinesin family member 11 decreases expression EXP Phenformin results in decreased expression of KIF11 mRNA CTD PMID:31324951 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Phenformin results in decreased expression of KIF20A mRNA CTD PMID:31324951 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Kif20b kinesin family member 20B decreases expression EXP Phenformin results in decreased expression of KIF20B mRNA CTD PMID:31324951 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Phenformin results in decreased expression of KIF23 mRNA CTD PMID:31324951 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Krt18 keratin 18 increases expression EXP Phenformin results in increased expression of KRT18 mRNA CTD PMID:31324951 NCBI chr 7:143,629,455...143,633,131
Ensembl chr 7:143,629,455...143,633,131
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Phenformin results in increased expression of LBP mRNA CTD PMID:31324951 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lepr leptin receptor increases response to substance EXP LEPR gene mutant form results in increased susceptibility to Phenformin CTD PMID:29743445 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals5 galectin 5 decreases expression EXP Phenformin results in decreased expression of LGALS5 mRNA CTD PMID:31324951 NCBI chr10:66,226,015...66,229,293
Ensembl chr10:66,225,995...66,229,311
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression EXP Phenformin results in decreased expression of LGSN mRNA CTD PMID:31324951 NCBI chr 9:37,458,603...37,490,117
Ensembl chr 9:37,462,693...37,490,108
JBrowse link
G Lipo1 lipase, member O1 decreases expression EXP Phenformin results in decreased expression of LIPO1 mRNA CTD PMID:31324951 NCBI chr 1:252,102,233...252,117,030
Ensembl chr 1:252,102,219...252,116,971
JBrowse link
G LOC100911204 protein CASC5-like decreases expression EXP Phenformin results in decreased expression of KNL1 mRNA CTD PMID:31324951 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression EXP Phenformin results in increased expression of LOXL4 mRNA CTD PMID:31324951 NCBI chr 1:261,833,365...261,853,599
Ensembl chr 1:261,835,992...261,853,495
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 increases expression EXP Phenformin results in increased expression of LPAR6 mRNA CTD PMID:31324951 NCBI chr15:55,126,953...55,128,762
Ensembl chr15:55,126,953...55,128,761
JBrowse link
G Lpin1 lipin 1 decreases expression EXP Phenformin results in decreased expression of LPIN1 mRNA CTD PMID:31324951 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Lum lumican decreases expression EXP Phenformin results in decreased expression of LUM mRNA CTD PMID:31324951 NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like decreases expression EXP Phenformin results in decreased expression of LURAP1L mRNA CTD PMID:31324951 NCBI chr 5:98,468,039...98,515,126
Ensembl chr 5:98,469,047...98,515,125
JBrowse link
G Ly6c Ly6-C antigen increases expression EXP Phenformin results in increased expression of LY6C mRNA CTD PMID:31324951
G Lynx1 Ly6/neurotoxin 1 decreases expression EXP Phenformin results in decreased expression of LYNX1 mRNA CTD PMID:31324951 NCBI chr 7:115,982,877...115,988,121
Ensembl chr 7:115,982,876...115,988,090
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression EXP Phenformin results in decreased expression of MASTL mRNA CTD PMID:31324951 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 increases expression EXP Phenformin results in increased expression of MBNL3 mRNA CTD PMID:31324951 NCBI chr  X:138,378,674...138,473,365
Ensembl chr  X:138,384,912...138,435,391
JBrowse link
G Mest mesoderm specific transcript decreases expression EXP Phenformin results in decreased expression of MEST mRNA CTD PMID:31324951 NCBI chr 4:58,052,786...58,063,227
Ensembl chr 4:58,053,041...58,063,138
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression EXP Phenformin results in decreased expression of MFAP4 mRNA CTD PMID:31324951 NCBI chr10:47,765,463...47,768,484
Ensembl chr10:47,765,432...47,768,483
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression EXP Phenformin results in decreased expression of MFSD2A mRNA CTD PMID:31324951 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP Phenformin results in decreased expression of MGAT4B mRNA CTD PMID:31324951 NCBI chr10:35,726,501...35,736,338
Ensembl chr10:35,726,544...35,736,338
JBrowse link
G Mgp matrix Gla protein decreases expression EXP Phenformin results in decreased expression of MGP mRNA CTD PMID:31324951 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mir15b microRNA 15b increases expression EXP Phenformin results in increased expression of MIR15B mRNA CTD PMID:31324951 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir29b2 microRNA 29b-2 increases expression EXP Phenformin results in increased expression of MIR29B2 mRNA CTD PMID:31324951 NCBI chr13:113,782,057...113,782,137
Ensembl chr13:113,782,057...113,782,140
JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP Phenformin results in increased expression of MIRLET7C-1 mRNA CTD PMID:31324951 NCBI chr11:16,052,873...16,052,966
Ensembl chr11:16,052,868...16,052,975
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Phenformin results in decreased expression of MKI67 mRNA CTD PMID:31324951 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression EXP Phenformin results in decreased expression of MKNK2 mRNA CTD PMID:31324951 NCBI chr 7:11,908,107...11,919,161
Ensembl chr 7:11,908,107...11,919,156
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression EXP Phenformin results in decreased expression of MLXIPL mRNA CTD PMID:31324951 NCBI chr12:24,590,645...24,619,639 JBrowse link
G Mst1r macrophage stimulating 1 receptor decreases expression EXP Phenformin results in decreased expression of MST1R mRNA CTD PMID:31324951 NCBI chr 8:116,686,601...116,700,132
Ensembl chr 8:116,686,601...116,700,132
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Phenformin results in increased expression of MT1A mRNA; Phenformin results in increased expression of MT1F mRNA; Phenformin results in increased expression of MT1M mRNA CTD PMID:31324951 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression EXP Phenformin results in increased expression of MT2A mRNA CTD PMID:31324951 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression EXP Phenformin results in decreased expression of MTSS1 mRNA CTD PMID:31324951 NCBI chr 7:98,820,799...98,960,878
Ensembl chr 7:98,820,812...98,960,837
JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression EXP Phenformin results in increased expression of MX2 mRNA CTD PMID:31324951 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Phenformin results in decreased expression of MYC mRNA CTD PMID:31324951 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Phenformin results in increased expression of MYH7 mRNA CTD PMID:31324951 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myoc myocilin increases expression EXP Phenformin results in increased expression of MYOC mRNA CTD PMID:31324951 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Myom2 myomesin 2 increases expression EXP Phenformin results in increased expression of MYOM2 mRNA CTD PMID:31324951 NCBI chr16:79,587,136...79,672,871
Ensembl chr16:79,587,640...79,671,719
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression EXP Phenformin results in decreased expression of NCAPG mRNA CTD PMID:31324951 NCBI chr14:69,898,268...69,927,885
Ensembl chr14:69,899,128...69,927,938
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Phenformin results in increased expression of NCF1 mRNA CTD PMID:31324951 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression EXP Phenformin results in decreased expression of NDC80 mRNA CTD PMID:31324951 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO Phenformin results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP Phenformin results in decreased expression of NFKBIA mRNA CTD PMID:31324951 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression EXP Phenformin results in decreased expression of NGEF mRNA CTD PMID:31324951 NCBI chr 9:94,569,286...94,601,852
Ensembl chr 9:94,569,286...94,601,852
JBrowse link
G Noct nocturnin decreases expression EXP Phenformin results in decreased expression of NOCT mRNA CTD PMID:31324951 NCBI chr 2:140,286,661...140,306,869
Ensembl chr 2:140,286,661...140,306,869
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Phenformin results in increased expression of NPPA mRNA CTD PMID:31324951 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Npr3 natriuretic peptide receptor 3 increases expression EXP Phenformin results in increased expression of NPR3 mRNA CTD PMID:31324951 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G Npy neuropeptide Y affects expression EXP Phenformin affects the expression of NPY mRNA CTD PMID:31324951 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Phenformin results in increased expression of NQO1 mRNA CTD PMID:31324951 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Phenformin results in increased expression of NR1D1 mRNA CTD PMID:31324951 NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP Phenformin results in increased expression of NR1D2 mRNA CTD PMID:31324951 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression EXP Phenformin results in decreased expression of NR4A1 mRNA CTD PMID:31324951 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP Phenformin results in decreased expression of NR4A2 mRNA CTD PMID:31324951 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression EXP Phenformin results in decreased expression of NR4A3 mRNA CTD PMID:31324951 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression EXP Phenformin results in decreased expression of NUF2 mRNA CTD PMID:31324951 NCBI chr13:87,818,456...87,847,223
Ensembl chr13:87,818,391...87,847,263
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression EXP Phenformin results in decreased expression of NUSAP1 mRNA CTD PMID:31324951 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Oaf out at first homolog increases expression EXP Phenformin results in increased expression of OAF mRNA CTD PMID:31324951 NCBI chr 8:47,511,718...47,529,689
Ensembl chr 8:47,511,719...47,529,689
JBrowse link
G Oat ornithine aminotransferase increases expression EXP Phenformin results in increased expression of OAT mRNA CTD PMID:31324951 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Olr906 olfactory receptor 906 increases expression EXP Phenformin results in increased expression of OLR906 mRNA CTD PMID:31324951 NCBI chr 4:13,610,125...13,611,059
Ensembl chr 7:5,450,324...5,451,262
JBrowse link
G Omd osteomodulin decreases expression EXP Phenformin results in decreased expression of OMD mRNA CTD PMID:31324951 NCBI chr17:15,476,100...15,484,324
Ensembl chr17:15,475,710...15,484,269
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like decreases expression EXP Phenformin results in decreased expression of OPCML mRNA CTD PMID:31324951 NCBI chr 8:28,842,202...29,967,300
Ensembl chr 8:29,453,643...29,962,825
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 decreases expression EXP Phenformin results in decreased expression of OSBPL3 mRNA CTD PMID:31324951 NCBI chr 4:80,025,453...80,202,532
Ensembl chr 4:80,025,440...80,107,884
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Phenformin results in decreased expression of OSGIN1 mRNA CTD PMID:31324951 NCBI chr19:52,056,808...52,085,491
Ensembl chr19:52,077,109...52,085,496
JBrowse link
G Otud1 OTU deubiquitinase 1 decreases expression EXP Phenformin results in decreased expression of OTUD1 mRNA CTD PMID:31324951 NCBI chr17:86,406,643...86,410,670
Ensembl chr17:86,408,151...86,409,518
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Phenformin results in increased expression of P2RX7 mRNA CTD PMID:31324951 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G P2ry2 purinergic receptor P2Y2 increases expression EXP Phenformin results in increased expression of P2RY2 mRNA CTD PMID:31324951 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression EXP Phenformin results in decreased expression of PAQR9 mRNA CTD PMID:31324951 NCBI chr 8:103,337,472...103,339,768
Ensembl chr 8:103,337,472...103,339,768
JBrowse link
G Pbk PDZ binding kinase decreases expression EXP Phenformin results in decreased expression of PBK mRNA CTD PMID:31324951 NCBI chr15:42,489,253...42,500,377
Ensembl chr15:42,489,377...42,500,395
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP Phenformin results in increased expression of PBLD1 mRNA CTD PMID:31324951 NCBI chr20:27,103,300...27,118,650
Ensembl chr20:27,103,317...27,117,663
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression EXP Phenformin results in decreased expression of PCLAF mRNA CTD PMID:31324951 NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
JBrowse link
G Pde4b phosphodiesterase 4B increases expression EXP Phenformin results in increased expression of PDE4B mRNA CTD PMID:31324951 NCBI chr 5:121,759,236...122,136,814
Ensembl chr 5:121,952,977...122,136,814
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Phenformin results in increased expression of PDK4 mRNA CTD PMID:31324951 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP Phenformin results in decreased expression of PDLIM1 mRNA CTD PMID:31324951 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP Phenformin results in decreased expression of PDLIM3 mRNA CTD PMID:31324951 NCBI chr16:49,543,140...49,574,362
Ensembl chr16:49,543,142...49,574,390
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 increases expression EXP Phenformin results in increased expression of PDZRN3 mRNA CTD PMID:31324951 NCBI chr 4:133,717,139...133,951,282
Ensembl chr 4:133,717,139...133,951,264
JBrowse link
G Penk proenkephalin increases expression EXP Phenformin results in increased expression of PENK mRNA CTD PMID:31324951 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of PER1 mRNA CTD PMID:31324951 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP Phenformin results in decreased expression of PER2 mRNA CTD PMID:31324951 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression EXP Phenformin results in increased expression of PEX11A mRNA CTD PMID:31324951 NCBI chr 1:141,474,189...141,481,270
Ensembl chr 1:141,474,180...141,481,315
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 increases expression EXP Phenformin results in increased expression of PEX16 mRNA CTD PMID:31324951 NCBI chr 3:81,283,137...81,292,575
Ensembl chr 3:81,283,137...81,292,573
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Phenformin results in decreased expression of PF4 mRNA CTD PMID:31324951 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression EXP Phenformin results in decreased expression of PFKFB1 mRNA CTD PMID:31324951 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 decreases expression EXP Phenformin results in decreased expression of PHTF1 mRNA CTD PMID:31324951 NCBI chr 2:206,452,115...206,518,387
Ensembl chr 2:206,454,208...206,493,030
JBrowse link
G Pi15 peptidase inhibitor 15 decreases expression EXP Phenformin results in decreased expression of PI15 mRNA CTD PMID:31324951 NCBI chr 5:791,137...819,233
Ensembl chr 5:790,833...819,326
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Phenformin results in decreased expression of PIK3R1 mRNA CTD PMID:31324951 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP Phenformin results in decreased expression of PKLR mRNA CTD PMID:31324951 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP Phenformin results in increased expression of PLA2G12A mRNA CTD PMID:31324951 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Plin2 perilipin 2 decreases expression EXP Phenformin results in decreased expression of PLIN2 mRNA CTD PMID:31324951 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plk1 polo-like kinase 1 decreases expression EXP Phenformin results in decreased expression of PLK1 mRNA CTD PMID:31324951 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression EXP Phenformin results in decreased expression of PLPPR1 mRNA CTD PMID:31324951 NCBI chr 5:67,852,817...67,985,310
Ensembl chr 5:67,852,180...68,139,199
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression EXP Phenformin results in decreased expression of PNPLA3 mRNA CTD PMID:31324951 NCBI chr 7:125,034,760...125,056,165
Ensembl chr 7:125,034,764...125,055,976
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression EXP Phenformin results in decreased expression of POR mRNA CTD PMID:31324951 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Potef POTE ankyrin domain family, member F decreases expression EXP Phenformin results in decreased expression of POTEF mRNA CTD PMID:31324951 NCBI chr18:24,780,521...24,783,147
Ensembl chr 3:75,643,054...75,644,954
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression EXP Phenformin results in decreased expression of PPARD mRNA CTD PMID:31324951 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP Phenformin results in increased expression of PPCS mRNA CTD PMID:31324951 NCBI chr 5:138,466,298...138,470,108
Ensembl chr 5:138,466,293...138,470,096
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression EXP Phenformin results in increased expression of PPM1K mRNA CTD PMID:31324951 NCBI chr 4:88,694,395...88,721,374
Ensembl chr 4:88,694,583...88,718,533
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression EXP Phenformin results in decreased expression of PPP1R15A mRNA CTD PMID:31324951 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP Phenformin results in decreased expression of PPP1R3B mRNA CTD PMID:31324951 NCBI chr16:60,415,192...60,427,498
Ensembl chr16:60,415,229...60,427,474
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression EXP Phenformin results in decreased expression of PRC1 mRNA CTD PMID:31324951 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression EXP Phenformin results in decreased expression of PRIM1 mRNA CTD PMID:31324951 NCBI chr 7:2,435,524...2,451,169
Ensembl chr 7:2,435,553...2,451,165
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prox1 prospero homeobox 1 increases expression EXP Phenformin results in increased expression of PROX1 mRNA CTD PMID:31324951 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
G Prrg4 proline rich and Gla domain 4 decreases expression EXP Phenformin results in decreased expression of PRRG4 mRNA CTD PMID:31324951 NCBI chr 3:94,783,866...94,808,861
Ensembl chr 3:94,784,008...94,808,861
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP Phenformin results in increased expression of PSMB8 mRNA CTD PMID:31324951 NCBI chr20:3,990,809...3,993,772
Ensembl chr20:3,990,613...3,993,769
JBrowse link
G Ptk6 protein tyrosine kinase 6 decreases expression EXP Phenformin results in decreased expression of PTK6 mRNA CTD PMID:31324951 NCBI chr 3:176,698,305...176,706,896
Ensembl chr 3:176,698,305...176,706,896
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression EXP Phenformin results in increased expression of PTPN3 mRNA CTD PMID:31324951 NCBI chr 5:74,248,996...74,368,167
Ensembl chr 5:74,248,996...74,368,186
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Phenformin results in increased expression of RAB30 mRNA CTD PMID:31324951 NCBI chr 1:157,573,344...157,667,973
Ensembl chr 1:157,573,324...157,660,008
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 decreases expression EXP Phenformin results in decreased expression of RAPGEF5 mRNA CTD PMID:31324951 NCBI chr 6:145,387,890...145,625,243
Ensembl chr 6:145,546,595...145,625,236
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Phenformin results in decreased expression of RCAN1 mRNA CTD PMID:31324951 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rdh5 retinol dehydrogenase 5 decreases expression EXP Phenformin results in decreased expression of RDH5 mRNA CTD PMID:31324951 NCBI chr 7:3,335,681...3,342,573
Ensembl chr 7:3,335,742...3,342,491
JBrowse link
G Reg3g regenerating family member 3 gamma increases expression EXP Phenformin results in increased expression of REG3G mRNA CTD PMID:31324951 NCBI chr 4:109,529,679...109,532,234
Ensembl chr 4:109,529,679...109,532,234
JBrowse link
G RGD1305184 similar to CDNA sequence BC023105 increases expression EXP Phenformin results in increased expression of RGD1305184 mRNA CTD PMID:31324951 NCBI chr18:55,634,615...55,669,634
Ensembl chr18:55,666,027...55,667,668
JBrowse link
G RGD1309362 similar to interferon-inducible GTPase increases expression EXP Phenformin results in increased expression of RGD1309362 mRNA CTD PMID:31324951 NCBI chr18:55,483,059...55,508,714
Ensembl chr18:55,505,993...55,508,704
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression EXP Phenformin results in decreased expression of RGD1309534 mRNA CTD PMID:31324951 NCBI chr 8:13,838,549...13,861,120
Ensembl chr 8:13,838,572...13,861,212
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 increases expression EXP Phenformin results in increased expression of RGD1559459 mRNA CTD PMID:31324951 NCBI chr14:22,932,454...22,955,663
Ensembl chr14:22,937,421...22,952,822
JBrowse link
G RGD1559887 similar to Transducin-like enhancer protein 4 (Groucho-related protein 4) (Grg-4) decreases expression EXP Phenformin results in decreased expression of RGD1559887 mRNA CTD PMID:31324951 NCBI chr 2:77,057,719...77,112,614 JBrowse link
G RGD1560288 similar to DNA segment, Chr 19, Brigham & Womens Genetics 1357 expressed increases expression EXP Phenformin results in increased expression of RGD1560288 mRNA CTD PMID:31324951 NCBI chr12:18,633,513...18,635,365 JBrowse link
G RGD1560801 similar to guanylate binding protein 1, interferon-inducible, 67kDa increases expression EXP Phenformin results in increased expression of RGD1560801 mRNA CTD PMID:31324951 NCBI chr 2:248,533,339...248,561,766 JBrowse link
G RGD1563850 similar to Aldo-keto reductase family 1, member B8 decreases expression EXP Phenformin results in decreased expression of RGD1563850 mRNA CTD PMID:31324951 NCBI chr 6:81,052,346...81,065,479 JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Phenformin results in decreased expression of RGS2 mRNA CTD PMID:31324951 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rp1 RP1, axonemal microtubule associated decreases expression EXP Phenformin results in decreased expression of RP1 mRNA CTD PMID:31324951 NCBI chr 5:15,005,028...15,060,508
Ensembl chr 5:15,043,955...15,060,508
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP Phenformin results in decreased expression of RRM2 mRNA CTD PMID:31324951 NCBI chr 6:43,884,627...43,890,818
Ensembl chr 6:43,884,678...43,889,515
JBrowse link
G RT1-A RT1 class I, locus A decreases expression EXP Phenformin results in decreased expression of RT1-A mRNA CTD PMID:31324951
G Sbk1 SH3 domain binding kinase 1 increases expression EXP Phenformin results in increased expression of SBK1 mRNA CTD PMID:31324951 NCBI chr 1:197,636,230...197,681,031
Ensembl chr 1:67,368,384...67,390,141
Ensembl chr 1:67,368,384...67,390,141
JBrowse link
G Scarna15 small Cajal body-specific RNA 15 decreases expression EXP Phenformin results in decreased expression of SCARNA15 mRNA CTD PMID:31324951 NCBI chr 1:143,360,224...143,360,287
Ensembl chr 1:143,360,224...143,360,287
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Phenformin results in decreased expression of SCD1 mRNA CTD PMID:31324951 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Phenformin results in decreased expression of SDC4 mRNA CTD PMID:31324951 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression EXP Phenformin results in increased expression of SDR42E1 mRNA CTD PMID:31324951 NCBI chr19:50,207,960...50,220,455
Ensembl chr19:50,207,980...50,220,455
JBrowse link
G Sds serine dehydratase increases expression EXP Phenformin results in increased expression of SDS mRNA CTD PMID:31324951 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP Phenformin results in increased expression of SERPINA7 mRNA CTD PMID:31324951 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Serpinc1 serpin family C member 1 increases activity ISO Phenformin results in increased activity of SERPINC1 protein CTD PMID:29458015 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Phenformin results in decreased expression of SERPINE1 mRNA CTD PMID:31324951 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Phenformin results in decreased expression of SIK1 mRNA CTD PMID:31324951 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO Phenformin results in decreased expression of SIRT1 protein CTD PMID:26768367 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression EXP Phenformin results in decreased expression of SLC10A2 mRNA CTD PMID:31324951 NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
JBrowse link
G Slc10a5 solute carrier family 10, member 5 decreases expression EXP Phenformin results in decreased expression of SLC10A5 mRNA CTD PMID:31324951 NCBI chr 2:93,669,962...93,671,266
Ensembl chr 2:93,669,765...93,671,457
JBrowse link
G Slc13a2 solute carrier family 13 member 2 decreases expression EXP Phenformin results in decreased expression of SLC13A2 mRNA CTD PMID:31324951 NCBI chr10:65,664,665...65,692,046
Ensembl chr10:65,664,667...65,692,023
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression EXP Phenformin results in increased expression of SLC13A3 mRNA CTD PMID:31324951 NCBI chr 3:162,084,336...162,147,398
Ensembl chr 3:162,084,315...162,147,393
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP Phenformin results in increased expression of SLC16A10 mRNA CTD PMID:31324951 NCBI chr20:45,138,433...45,260,155
Ensembl chr20:45,143,453...45,260,119
JBrowse link
G Slc17a9 solute carrier family 17 member 9 decreases expression EXP Phenformin results in decreased expression of SLC17A9 mRNA CTD PMID:31324951 NCBI chr 3:176,228,433...176,246,971
Ensembl chr 3:176,230,378...176,246,953
JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:88,762,775...88,828,553
Ensembl chr 9:88,764,073...88,816,898
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Phenformin results in increased expression of SLC1A2 mRNA CTD PMID:31324951 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression EXP Phenformin results in increased expression of SLC1A4 mRNA CTD PMID:31324951 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a23 solute carrier family 22, member 23 decreases expression EXP Phenformin results in decreased expression of SLC22A23 mRNA CTD PMID:31324951 NCBI chr17:31,236,015...31,403,685
Ensembl chr17:31,236,015...31,403,685
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases response to substance
affects uptake
ISO SLC22A4 protein results in increased susceptibility to Phenformin
SLC22A4 protein affects the uptake of Phenformin
CTD PMID:23221006 NCBI chr10:39,334,972...39,373,508 JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Phenformin results in increased expression of SLC22A5 mRNA CTD PMID:31324951 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc25a23 solute carrier family 25 member 23 decreases expression EXP Phenformin results in decreased expression of SLC25A23 mRNA CTD PMID:31324951 NCBI chr 9:9,987,988...10,003,599
Ensembl chr 9:9,988,055...10,001,962
JBrowse link
G Slc25a47 solute carrier family 25, member 47 increases expression EXP Phenformin results in increased expression of SLC25A47 mRNA CTD PMID:31324951 NCBI chr 6:132,762,306...132,767,940
Ensembl chr 6:132,762,280...132,768,379
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression EXP Phenformin results in increased expression of SLC27A1 mRNA CTD PMID:31324951 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc2a12 solute carrier family 2 member 12 increases expression EXP Phenformin results in increased expression of SLC2A12 mRNA CTD PMID:31324951 NCBI chr 1:24,003,625...24,056,373
Ensembl chr 1:24,003,625...24,056,373
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression EXP Phenformin results in decreased expression of SLC2A5 mRNA CTD PMID:31324951 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Phenformin results in decreased expression of SLC34A2 mRNA CTD PMID:31324951 NCBI chr14:60,257,211...60,276,516
Ensembl chr14:60,256,712...60,276,794
JBrowse link
G Slc35c2 solute carrier family 35 member C2 decreases expression EXP Phenformin results in decreased expression of SLC35C2 mRNA CTD PMID:31324951 NCBI chr 3:161,801,194...161,812,318
Ensembl chr 3:161,801,197...161,812,291
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression EXP Phenformin results in decreased expression of SLC38A2 mRNA CTD PMID:31324951 NCBI chr 7:138,088,654...138,100,869
Ensembl chr 7:138,088,649...138,100,841
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Phenformin inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) decreases expression EXP Phenformin results in decreased expression of SLC4A1 mRNA CTD PMID:31324951 NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Phenformin results in increased expression of SLC4A4 mRNA CTD PMID:31324951 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Phenformin results in increased expression of SLC6A6 mRNA CTD PMID:31324951 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Smco1 single-pass membrane protein with coiled-coil domains 1 increases expression EXP Phenformin results in increased expression of SMCO1 mRNA CTD PMID:31324951 NCBI chr11:71,747,457...71,750,147
Ensembl chr11:71,754,902...71,757,801
Ensembl chr11:71,754,902...71,757,801
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression EXP Phenformin results in increased expression of SNAI2 mRNA CTD PMID:31324951 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Sntb1 syntrophin, beta 1 increases expression EXP Phenformin results in increased expression of SNTB1 mRNA CTD PMID:31324951 NCBI chr 7:95,395,417...95,670,093
Ensembl chr 7:95,397,113...95,669,809
JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression EXP Phenformin results in decreased expression of SOCS2 mRNA CTD PMID:31324951 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP Phenformin results in increased expression of SPINK1 mRNA CTD PMID:31324951 NCBI chr18:38,221,919...38,242,092
Ensembl chr18:38,221,681...38,242,119
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Phenformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Phenformin results in decreased expression of STAC3 mRNA CTD PMID:31324951 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Phenformin results in increased expression of STAT3 mRNA CTD PMID:31324951 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Phenformin results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Phenformin results in decreased expression of STMN1 mRNA CTD PMID:31324951 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Stxbp6 syntaxin binding protein 6 increases expression EXP Phenformin results in increased expression of STXBP6 mRNA CTD PMID:31324951 NCBI chr 6:65,086,483...65,319,527
Ensembl chr 6:65,089,318...65,319,527
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression EXP Phenformin results in increased expression of TBX3 mRNA CTD PMID:31324951 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tcap titin-cap increases expression EXP Phenformin results in increased expression of TCAP mRNA CTD PMID:31324951 NCBI chr10:86,337,705...86,338,414
Ensembl chr10:86,337,728...86,338,411
JBrowse link
G Tex36 testis expressed 36 increases expression EXP Phenformin results in increased expression of TEX36 mRNA CTD PMID:31324951 NCBI chr 1:205,615,759...205,630,073
Ensembl chr 1:205,615,761...205,669,760
JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Phenformin results in increased expression of THBS1 mRNA CTD PMID:31324951 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP Phenformin results in decreased expression of THRSP mRNA CTD PMID:31324951 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tk1 thymidine kinase 1 decreases expression EXP Phenformin results in decreased expression of TK1 mRNA CTD PMID:31324951 NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression EXP Phenformin results in decreased expression of TKFC mRNA CTD PMID:31324951 NCBI chr 1:226,642,901...226,657,698
Ensembl chr 1:226,644,200...226,657,408
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Phenformin results in increased expression of TM7SF2 mRNA CTD PMID:31324951 NCBI chr 1:221,426,017...221,430,340
Ensembl chr 1:221,425,987...221,431,713
JBrowse link
G Tmem30b transmembrane protein 30B increases expression EXP Phenformin results in increased expression of TMEM30B mRNA CTD PMID:31324951 NCBI chr 6:96,439,607...96,442,682
Ensembl chr 6:96,439,607...96,442,682
JBrowse link
G Tmem37 transmembrane protein 37 decreases expression EXP Phenformin results in decreased expression of TMEM37 mRNA CTD PMID:31324951 NCBI chr13:36,094,665...36,101,443
Ensembl chr13:36,094,520...36,101,411
JBrowse link
G Tmod4 tropomodulin 4 increases expression EXP Phenformin results in increased expression of TMOD4 mRNA CTD PMID:31324951 NCBI chr 2:196,294,990...196,299,896
Ensembl chr 2:196,295,069...196,299,896
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression EXP Phenformin results in increased expression of TNFAIP2 mRNA CTD PMID:31324951 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression EXP Phenformin results in decreased expression of TNFAIP3 mRNA CTD PMID:31324951 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfsf13 TNF superfamily member 13 decreases expression EXP Phenformin results in decreased expression of TNFSF13 mRNA CTD PMID:31324951 NCBI chr10:56,286,964...56,290,680
Ensembl chr10:56,286,887...56,289,952
JBrowse link
G Tob2 transducer of ERBB2, 2 decreases expression EXP Phenformin results in decreased expression of TOB2 mRNA CTD PMID:31324951 NCBI chr 7:123,079,520...123,088,240
Ensembl chr 7:123,079,537...123,088,279
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Phenformin results in decreased expression of TOP2A mRNA CTD PMID:31324951 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression EXP Phenformin results in decreased expression of TP53INP1 mRNA CTD PMID:31324951 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tppp tubulin polymerization promoting protein decreases expression EXP Phenformin results in decreased expression of TPPP mRNA CTD PMID:31324951 NCBI chr 1:31,866,755...31,890,778
Ensembl chr 1:31,870,899...31,890,778
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression EXP Phenformin results in decreased expression of TPX2 mRNA CTD PMID:31324951 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187
JBrowse link
G Trim24 tripartite motif-containing 24 increases expression EXP Phenformin results in increased expression of TRIM24 mRNA CTD PMID:31324951 NCBI chr 4:65,632,278...65,684,746
Ensembl chr 4:65,637,407...65,684,743
JBrowse link
G Trim50 tripartite motif-containing 50 increases expression EXP Phenformin results in increased expression of TRIM50 mRNA CTD PMID:31324951 NCBI chr12:24,348,426...24,365,467
Ensembl chr12:24,348,321...24,365,324
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression EXP Phenformin results in decreased expression of TSC22D3 mRNA CTD PMID:31324951 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan decreases expression EXP Phenformin results in decreased expression of TSKU mRNA CTD PMID:31324951 NCBI chr 1:163,317,281...163,328,697
Ensembl chr 1:163,317,282...163,328,591
JBrowse link
G Tspan4 tetraspanin 4 decreases expression EXP Phenformin results in decreased expression of TSPAN4 mRNA CTD PMID:31324951 NCBI chr 1:214,454,090...214,473,789
Ensembl chr 1:214,454,090...214,473,741
JBrowse link
G Ttk Ttk protein kinase decreases expression EXP Phenformin results in decreased expression of TTK mRNA CTD PMID:31324951 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Tubb1 tubulin, beta 1 class VI decreases expression EXP Phenformin results in decreased expression of TUBB1 mRNA CTD PMID:31324951 NCBI chr 3:172,550,252...172,558,089
Ensembl chr 3:172,550,258...172,558,114
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Phenformin results in decreased expression of TUBB2A mRNA CTD PMID:31324951 NCBI chr17:31,493,145...31,496,827
Ensembl chr17:31,493,107...31,498,651
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP Phenformin results in increased expression of TXNIP mRNA CTD PMID:31324951 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP Phenformin results in decreased expression of UBE2C mRNA CTD PMID:31324951 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Phenformin results in increased expression of UCP3 mRNA CTD PMID:31324951 NCBI chr 1:165,482,912...165,495,895
Ensembl chr 1:165,482,155...165,496,206
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP Phenformin results in decreased expression of UGDH protein CTD PMID:4270849 NCBI chr14:44,479,614...44,502,845
Ensembl chr14:44,479,614...44,502,845
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 increases expression EXP Phenformin results in increased expression of UGT2A3 mRNA CTD PMID:31324951 NCBI chr14:22,251,507...22,267,899
Ensembl chr14:22,192,970...22,619,968
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP Phenformin results in increased expression of UGT2B1 mRNA CTD PMID:31324951 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Upp2 uridine phosphorylase 2 increases expression EXP Phenformin results in increased expression of UPP2 mRNA CTD PMID:31324951 NCBI chr 3:44,806,106...44,846,464
Ensembl chr 3:44,806,106...44,846,464
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression EXP Phenformin results in increased expression of USP18 mRNA CTD PMID:31324951 NCBI chr 4:153,812,312...153,834,374
Ensembl chr 4:153,805,993...153,834,430
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP Phenformin results in decreased expression of USP2 mRNA CTD PMID:31324951 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Vgll4 vestigial-like family member 4 decreases expression EXP Phenformin results in decreased expression of VGLL4 mRNA CTD PMID:31324951 NCBI chr 4:146,778,556...146,890,063
Ensembl chr 4:146,779,276...146,839,397
JBrowse link
G Vnn1 vanin 1 increases expression EXP Phenformin results in increased expression of VNN1 mRNA CTD PMID:31324951 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression EXP Phenformin results in decreased expression of WEE1 mRNA CTD PMID:31324951 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP Phenformin results in increased expression of XIAP mRNA CTD PMID:31324951 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Ypel2 yippee-like 2 decreases expression EXP Phenformin results in decreased expression of YPEL2 mRNA CTD PMID:31324951 NCBI chr10:74,241,032...74,298,691
Ensembl chr10:74,243,812...74,298,599
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression EXP Phenformin results in decreased expression of ZBTB16 mRNA CTD PMID:31324951 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
G Zfp354a zinc finger protein 354A decreases expression EXP Phenformin results in decreased expression of ZFP354A mRNA CTD PMID:31324951 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
G Zfp36 zinc finger protein 36 decreases expression EXP Phenformin results in decreased expression of ZFP36 mRNA CTD PMID:31324951 NCBI chr 1:85,380,088...85,382,565
Ensembl chr 1:85,380,088...85,382,569
JBrowse link
G Znf750 zinc finger protein 750 increases expression EXP Phenformin results in increased expression of ZNF750 mRNA CTD PMID:31324951 NCBI chr10:110,698,581...110,701,222
Ensembl chr10:110,698,891...110,701,137
JBrowse link
proguanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases metabolic processing
decreases activity
ISO CYP2C19 protein results in increased metabolism of Proguanil
Proguanil results in decreased activity of CYP2C19 protein
CTD PMID:11124226 PMID:12464242 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Proguanil results in decreased activity of CYP2D6 protein CTD PMID:11124226 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Proguanil inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Proguanil inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            hypoglycemic agent 4036
              biguanides 441
                Buformin 0
                N-(diaminomethylidene)-4-morpholinecarboximidamide 0
                alexidine 7
                chlorhexidine + 3
                m-Chlorophenylbiguanide 2
                phenformin 423
                proguanil 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      p-block molecular entity 19696
                        carbon group molecular entity 19599
                          organic molecular entity 19588
                            heteroorganic entity 19175
                              organonitrogen compound 18335
                                guanidines 2171
                                  biguanides 441
                                    Buformin 0
                                    N-(diaminomethylidene)-4-morpholinecarboximidamide 0
                                    alexidine 7
                                    chlorhexidine + 3
                                    m-Chlorophenylbiguanide 2
                                    phenformin 423
                                    proguanil 4
paths to the root