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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:conduritol epoxide
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Accession:CHEBI:67235 term browser browse the term
Definition:An epoxide resulting from the epoxidation of the double bond of a conduritol.
Synonyms:exact_synonym: 7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
 related_synonym: Formula=C6H10O5;   InChI=1S/C6H10O5/c7-1-2(8)4(10)6-5(11-6)3(1)9/h1-10H;   InChIKey=ZHMWOVGZCINIHW-UHFFFAOYSA-N;   SMILES=OC1C(O)C(O)C2OC2C1O


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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 multiple interactions
decreases activity		 ISO
EXP		 [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA1 protein
[conduritol epoxide binds to and results in decreased activity of GBA1 protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein		 CTD PMID:9101438 PMID:19576930 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA1 protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      molecular entity 19919
        main group molecular entity 19865
          gas molecular entity 18507
            oxirane 11275
              epoxide 11274
                conduritol epoxide 2
                  1-D-1,2-anhydro-myo-inositol + 2
                  1-L-1,2-anhydro-myo-inositol + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    main group molecular entity 19865
                      s-block molecular entity 19697
                        hydrogen molecular entity 19678
                          hydrides 19184
                            organic hydride 18719
                              organic fundamental parent 18719
                                hydrocarbon 18462
                                  olefin 8938
                                    cyclic olefin 416
                                      monocyclic olefin 413
                                        cycloalkene 406
                                          cyclohexene 3
                                            conduritol 2
                                              conduritol epoxide 2
                                                1-D-1,2-anhydro-myo-inositol + 2
                                                1-L-1,2-anhydro-myo-inositol + 2
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