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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:conduritol
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Accession:CHEBI:67218 term browser browse the term
Definition:A tetrol that is cyclohexene in which a hydrogen attached to each of the carbons at positions 3, 4, 5, and 6 is replaced by a hydroxy group. The group consists of six possible diastereoisomers, known as conduritols A to F, some of which can exist as two distinct enantiomers.
Synonyms:exact_synonym: cyclohex-5-ene-1,2,3,4-tetrol
 related_synonym: Formula=C6H10O4;   InChI=1S/C6H10O4/c7-3-1-2-4(8)6(10)5(3)9/h1-10H;   InChIKey=LRUBQXAKGXQBHA-UHFFFAOYSA-N;   SMILES=OC1C=CC(O)C(O)C1O
 xref: PMID:12003543;   PMID:16267592;   PMID:21630704;   Wikipedia:Conduritol


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conduritol B epoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta multiple interactions
decreases activity
ISO
EXP
[conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
[conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein
conduritol epoxide analog results in decreased activity of GBA protein
CTD PMID:9101438 PMID:19576930 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Snca synuclein alpha multiple interactions ISO [conduritol epoxide binds to and results in decreased activity of GBA protein] which affects the localization of SNCA protein; [conduritol epoxide binds to and results in decreased activity of GBA protein] which results in increased expression of SNCA protein CTD PMID:19576930 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      molecular entity 19811
        polyatomic entity 19732
          heteroatomic molecular entity 19673
            hydroxides 19175
              organic hydroxy compound 18668
                polyol 8079
                  cyclitol 2458
                    conduritol 2
                      (+)-conduritol B + 2
                      (-)-conduritol B + 2
                      conduritol A 0
                      conduritol epoxide + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            organic hydride 18354
                              organic fundamental parent 18354
                                hydrocarbon 18065
                                  olefin 5478
                                    cyclic olefin 108
                                      monocyclic olefin 105
                                        cycloalkene 96
                                          cyclohexene 3
                                            conduritol 2
                                              (+)-conduritol B + 2
                                              (-)-conduritol B + 2
                                              conduritol A 0
                                              conduritol epoxide + 2
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