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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phosphatidylcholine
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Accession:CHEBI:64482 term browser browse the term
Definition:A glycerophosphocholine that is glycero-3-phosphocholine bearing two acyl substituents at positions 1 and 2.
Synonyms:exact_synonym: 2,3-bis(acyloxy)propyl 2-(trimethylammonio)ethyl phosphate
 related_synonym: 1,2-diacyl-glycero-3-phosphocholine;   Formula=C10H18NO8PR2;   SMILES=C[N+](C)(C)CCOP([O-])(=O)OCC(COC([*])=O)OC([*])=O;   a phosphatidylcholine (0)
 alt_id: MESH:D010713
 xref_mesh: MESH:D010713
 xref: PMID:2474544
 cyclic_relationship: is_conjugate_base_of CHEBI:49183



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phosphatidylcholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB4 ATP binding cassette subfamily B member 4 increases export
multiple interactions
EXP ABCB4 protein results in increased export of Phosphatidylcholines
Itraconazole inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]; Verapamil inhibits the reaction [ABCB4 protein results in increased export of Phosphatidylcholines]
CTD PMID:21056966 NCBI chr 9:93,171,371...93,262,124 JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 increases hydrolysis EXP PDIA3 protein results in increased hydrolysis of Phosphatidylcholines CTD PMID:16798117 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5082
    role 5047
      biological role 5047
        osmolyte 15
          glycerol 15
            glycerolipid 2
              glycerophospholipid 2
                glycerophosphocholine 2
                  phosphatidylcholine 2
                    1,2-diacyl-sn-glycero-3-phosphocholine + 0
                    dimyristoyl phosphatidylcholine 0
                    phosphatidylcholine 37:1 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5082
    subatomic particle 5073
      composite particle 5073
        hadron 5073
          baryon 5073
            nucleon 5073
              atomic nucleus 5073
                atom 5073
                  main group element atom 5043
                    p-block element atom 5040
                      chalcogen 4946
                        oxygen atom 4913
                          oxygen molecular entity 4913
                            hydroxides 4864
                              oxoacid 412
                                pnictogen oxoacid 87
                                  phosphorus oxoacid 85
                                    phosphoric acids 54
                                      phosphoric acid 54
                                        phosphoric acid derivative 50
                                          phosphate 50
                                            organic phosphate 50
                                              phospholipid 2
                                                glycerophospholipid 2
                                                  glycerophosphocholine 2
                                                    phosphatidylcholine 2
                                                      1,2-diacyl-sn-glycero-3-phosphocholine + 0
                                                      dimyristoyl phosphatidylcholine 0
                                                      phosphatidylcholine 37:1 0
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