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Gene: ABCB4 (ATP binding cassette subfamily B member 4) Sus scrofa
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Symbol: ABCB4
Name: ATP binding cassette subfamily B member 4
Description: ENCODES a protein that exhibits ATP binding (inferred); ATPase activity (inferred); ATPase-coupled transmembrane transporter activity (inferred); INVOLVED IN transmembrane transport (inferred); PARTICIPATES IN bile acid transport pathway; multidrug resistance protein mediated transport pathway; ASSOCIATED WITH Animal Disease Models (ortholog); cholangitis (ortholog); cholecystitis (ortholog); FOUND IN integral component of membrane (inferred); INTERACTS WITH 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one; itraconazole
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATP-binding cassette, sub-family B (MDR/TAP), member 4; MDR3; multidrug resistance 3; P-glycoprotein class III; Pgp3; phosphatidylcholine translocator ABCB4
Orthologs:
Homo sapiens (human) : ABCB4 (ATP binding cassette subfamily B member 4)  HGNC  Alliance
Mus musculus (house mouse) : Abcb4 (ATP-binding cassette, sub-family B (MDR/TAP), member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Abcb4 (ATP binding cassette subfamily B member 4)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ABCB4 (ATP binding cassette subfamily B member 4)
Canis lupus familiaris (dog) : ABCB4 (ATP binding cassette subfamily B member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abcb4 (ATP binding cassette subfamily B member 4)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1993,171,371 - 93,262,124 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29102,651,665 - 102,741,039 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ABCB4
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 14031420
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.