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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hymexazol
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Accession:CHEBI:5827 term browser browse the term
Definition:A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals.
Synonyms:exact_synonym: 5-methyl-1,2-oxazol-3(2H)-one
 related_synonym: 3-Hydroxy-5-methylisoxazole;   5-Methyl-3(2H)-isoxazolone;   5-Methyl-3-hydroxyisoxazole;   5-Methylisoxazol-3-ol;   F-319;   Formula=C4H5NO2;   Hydroxyisoxazole;   Hymexazole;   InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6);   InChIKey=KGVPNLBXJKTABS-UHFFFAOYSA-N;   NSC 217971;   SF-6505;   SMILES=Cc1cc(O)no1
 xref: CAS:10004-44-1;   KEGG:C11103
 xref_mesh: MESH:C531211
 xref: PMID:21959994;   PMID:22307860;   PPDB:388;   Pesticides:hymexazol;   Reaxys:606046


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hymexazol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression EXP hymexazol results in increased expression of BAX mRNA CTD PMID:35773501 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP hymexazol results in decreased expression of BCL2 mRNA CTD PMID:35773501 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases expression EXP hymexazol results in increased expression of CASP3 protein CTD PMID:35773501 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases activity EXP hymexazol results in decreased activity of CAT protein CTD PMID:35773501 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP hymexazol results in increased expression of MAPK8 mRNA CTD PMID:35773501 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        pesticide 18059
          antifungal agrochemical 12051
            hymexazol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic heterocyclic compound 18881
                                  heteroarene 17148
                                    monocyclic heteroarene 14977
                                      azole 14500
                                        oxazole 3646
                                          isoxazoles 3121
                                            hymexazol 5
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