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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-valerolactone
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Accession:CHEBI:48569 term browser browse the term
Definition:A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a methyl group at position 5. It has been found in the urine samples of humans exposed to n-hexane.
Synonyms:exact_synonym: 5-methyldihydrofuran-2(3H)-one
 related_synonym: 4-Hydroxypentanoic acid lactone;   4-Hydroxyvaleric acid lactone;   4-Methyl-4-hydroxybutanoic acid lactone;   4-Methyl-gamma-butyrolactone;   4-Pentanolide;   4-Valerolactone;   Formula=C5H8O2;   InChI=1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3;   InChIKey=GAEKPEKOJKCEMS-UHFFFAOYSA-N;   SMILES=CC1CCC(=O)O1;   dihydro-5-methyl-2(3H)-furanone;   gamma-Pentalactone;   gamma-Pentanolactone
 xref: Beilstein:80420;   CAS:108-29-2;   HMDB:HMDB0033840
 xref_mesh: MESH:C037556
 xref: PMID:23486087;   PMID:7470400;   Patent:CN101633649;   Reaxys:80420;   Wikipedia:Gamma-Valerolactone


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gamma-valerolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 decreases activity EXP gamma-valerolactone results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      application 25177
        food additive 18331
          flavouring agent 4778
            gamma-valerolactone 1
              (R)-gamma-valerolactone 0
              (S)-gamma-valerolactone 0
              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    p-block element atom 25840
                      carbon group element atom 25437
                        carbon atom 25395
                          organic molecular entity 25395
                            heteroorganic entity 24770
                              organochalcogen compound 24383
                                organooxygen compound 24060
                                  ester 18815
                                    carboxylic ester 17956
                                      lactone 13632
                                        gamma-lactone 6954
                                          butan-4-olide 308
                                            gamma-valerolactone 1
                                              (R)-gamma-valerolactone 0
                                              (S)-gamma-valerolactone 0
                                              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
                                              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
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