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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:dicyclomine
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Accession:CHEBI:4514 term browser browse the term
Definition:The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.
Synonyms:exact_synonym: 2-(diethylamino)ethyl 1,1'-bi(cyclohexyl)-1-carboxylate
 related_synonym: 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate;   Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester;   Dicycloverin;   Formula=C19H35NO2;   InChI=1S/C19H35NO2/c1-3-20(4-2)15-16-22-18(21)19(13-9-6-10-14-19)17-11-7-5-8-12-17/h17H,3-16H2,1-2H3;   InChIKey=CURUTKGFNZGFSE-UHFFFAOYSA-N;   SMILES=CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1;   dicicloverina;   dicycloverine;   dicycloverinum
 alt_id: CHEBI:265774
 xref: Beilstein:2282819;   CAS:77-19-0;   DrugBank:DB00804;   Drug_Central:868;   KEGG:C06951;   KEGG:D07820;   LINCS:LSM-3534
 xref_mesh: MESH:D004025
 xref: Patent:US2474796;   Wikipedia:Dicyclomine


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dicyclomine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Dicyclomine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        NMR chemical shift reference compound 17938
          ammonia 17797
            organic amino compound 17797
              amine 8269
                tertiary amine 640
                  dicyclomine 1
                    dicyclomine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        amino alcohol 1069
                                          ethanolamines 819
                                            ethanolamine 89
                                              2-diethylaminoethanol 25
                                                dicyclomine 1
                                                  dicyclomine hydrochloride 0
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