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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sebacic acid
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Accession:CHEBI:41865 term browser browse the term
Definition:An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.
Synonyms:related_synonym: 1,10-decanedioic acid;   1,8-dicarboxyoctane;   Decanedioic acid;   Formula=C10H18O4;   InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14);   InChIKey=CXMXRPHRNRROMY-UHFFFAOYSA-N;   SMILES=OC(=O)CCCCCCCCC(O)=O;   Sebacinsaeure
 alt_id: CHEBI:41860;   CHEBI:9071
 xref: Beilstein:1210591;   CAS:111-20-6;   DrugBank:DB07645;   Gmelin:102423;   HMDB:HMDB0000792;   KEGG:C08277;   KNApSAcK:C00001202;   LIPID_MAPS_instance:LMFA01170006
 xref_mesh: MESH:C011107
 xref: MetaCyc:CPD-3623;   PDBeChem:DEC;   PMID:22770225;   PMID:9439441;   Reaxys:1210591;   Wikipedia:Sebacic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:132954;   is_conjugate_acid_of CHEBI:76283


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sebacic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO sebacic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] CTD PMID:19428350 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of sebacic acid analog; [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of sebacic acid analog CTD PMID:26820058 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO sebacic acid results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO sebacic acid results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        biochemical role 19529
          metabolite 19515
            eukaryotic metabolite 19337
              plant metabolite 17962
                sebacic acid 4
                  3-hydroxysebacic acid 0
                  decanedioyl-CoA 0
                  dimethyl sebacate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      monocarboxylic acid 18008
                                        fatty acid 16809
                                          fatty acid derivative 8969
                                            dicarboxylic fatty acid 2650
                                              sebacic acid 4
                                                3-hydroxysebacic acid 0
                                                decanedioyl-CoA 0
                                                dimethyl sebacate 0
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