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pinitol - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pinitol
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Accession:CHEBI:37208 term browser browse the term
Definition:A cyclitol ether formed by etherification of the 3-hydroxy group of chiro-inositol. It is plant metabolite isolated from the leaves of Sutherlandia frutescens.
Synonyms:exact_synonym: 3-O-methyl-chiro-inositol
 related_synonym: Formula=C7H14O6
 xref: CAS:484-68-4
 xref_mesh: MESH:C021730
 xref: PMID:24374864;   PMID:24503502

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show annotations for term's descendants           Sort by:
pinitol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP
ISO 		pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
pinitol inhibits the reaction [Cisplatin results in decreased activity of CAT protein] 		CTD PMID:20643114 PMID:29752894 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO 		pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]
pinitol inhibits the reaction [Cisplatin results in increased expression of IL1B protein] 		CTD PMID:20643114 PMID:29752894 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO 		pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
pinitol inhibits the reaction [Cisplatin results in increased expression of IL6 protein] 		CTD PMID:20643114 PMID:29752894 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP pinitol inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:20643114 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO 		pinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]
pinitol inhibits the reaction [Cisplatin results in increased expression of TNF protein] 		CTD PMID:20643114 PMID:29752894 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    role 20805
      application 20606
        pharmaceutical 20401
          drug 20401
            hypoglycemic agent 4237
              pinitol 5
                D-pinitol 0
                L-pinitol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      chalcogen 20477
                        oxygen atom 20443
                          oxygen molecular entity 20443
                            hydroxides 20216
                              organic hydroxy compound 19754
                                polyol 11886
                                  cyclitol 7550
                                    inositol 58
                                      chiro-inositol 5
                                        pinitol 5
                                          D-pinitol 0
                                          L-pinitol 0
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