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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glutaryl-CoA
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Accession:CHEBI:15524 term browser browse the term
Definition:An omega-carboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of glutaric acid.
Synonyms:exact_synonym: 3'-phosphoadenosine 5'-{3-[(3R)-4-{[3-({2-[(4-carboxybutanoyl)sulfanyl]ethyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl] dihydrogen diphosphate}
 related_synonym: 4-carboxybutanoyl-CoA;   4-carboxybutanoyl-coenzyme A;   Formula=C26H42N7O19P3S;   InChI=1S/C26H42N7O19P3S/c1-26(2,21(39)24(40)29-7-6-15(34)28-8-9-56-17(37)5-3-4-16(35)36)11-49-55(46,47)52-54(44,45)48-10-14-20(51-53(41,42)43)19(38)25(50-14)33-13-32-18-22(27)30-12-31-23(18)33/h12-14,19-21,25,38-39H,3-11H2,1-2H3,(H,28,34)(H,29,40)(H,35,36)(H,44,45)(H,46,47)(H2,27,30,31)(H2,41,42,43)/t14-,19-,20-,21+,25-/m1/s1;   InChIKey=SYKWLIJQEHRDNH-CKRMAKSASA-N;   SMILES=CC(C)(COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n1cnc2c(N)ncnc12)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCCC(O)=O;   coenzyme A, S-(hydrogen pentanedioate);   glutaryl-coenzyme A
 alt_id: CHEBI:14326;   CHEBI:24332;   CHEBI:5436
 xref: CAS:3131-84-8;   HMDB:HMDB0001339;   KEGG:C00527
 xref_mesh: MESH:C015901
 xref: PDBeChem:GRA;   PMID:11024031;   PMID:3971969;   PMID:6547838;   PMID:853337;   PMID:8722121;   UM-BBD_compID:c0222
 cyclic_relationship: is_conjugate_acid_of CHEBI:57378


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glutaryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          cofactor 16151
            coenzyme 1014
              coenzyme A 29
                glutaryl-CoA 2
                  2-hydroxyglutaryl-CoA + 0
                  3-hydroxy-3-methylglutaryl-CoA + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      chalcogen 19513
                        oxygen atom 19488
                          oxygen molecular entity 19488
                            hydroxides 19299
                              oxoacid 18736
                                pnictogen oxoacid 13211
                                  phosphorus oxoacid 12414
                                    phosphoric acids 11418
                                      phosphoric acid 11418
                                        phosphoric acid derivative 11227
                                          phosphate 11226
                                            organic phosphate 11226
                                              carbohydrate phosphate 1854
                                                phospho sugar 1699
                                                  aldose phosphate 1696
                                                    aldopentose phosphate 1688
                                                      ribose phosphate 1683
                                                        ribonucleotide 1644
                                                          purine ribonucleotide 1611
                                                            adenyl ribonucleotide 1304
                                                              adenosine phosphate 296
                                                                adenosine 5'-phosphate 295
                                                                  ADP 88
                                                                    coenzyme A 29
                                                                      acyl-CoA 29
                                                                        omega-carboxyacyl-CoA 2
                                                                          glutaryl-CoAs 2
                                                                            glutaryl-CoA 2
                                                                              2-hydroxyglutaryl-CoA + 0
                                                                              3-hydroxy-3-methylglutaryl-CoA + 0
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