|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions affects binding |
ISO |
estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein mutant form]; estradiol-17 beta-glucuronide inhibits the reaction [Adenosine Diphosphate binds to ABCC1 protein]; Vanadates promotes the reaction [Adenosine Diphosphate binds to ABCC1 protein] Adenosine Diphosphate binds to ABCC1 protein; Adenosine Diphosphate binds to ABCC1 protein mutant form |
CTD |
PMID:18336795 |
|
NCBI chr10:1,022,041...1,162,431
|
|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
EXP |
Adenosine Diphosphate affects the folding of [Tetrachlorodibenzodioxin binds to AHR protein] |
CTD |
PMID:1848756 |
|
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Ak1 |
adenylate kinase 1 |
increases abundance |
ISO |
AK1 protein results in increased abundance of Adenosine Diphosphate |
CTD |
PMID:11390963 |
|
NCBI chr 3:36,310,113...36,320,760
|
|
G |
Alb |
albumin |
decreases secretion multiple interactions |
ISO |
Adenosine Diphosphate results in decreased secretion of ALB protein Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein] |
CTD |
PMID:17303692 |
|
NCBI chr14:17,891,564...17,907,043
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions increases abundance |
ISO |
PF-06840003 inhibits the reaction [APP protein mutant form results in increased abundance of Adenosine Diphosphate] [APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate] |
CTD |
PMID:39172838 |
|
NCBI chr11:37,506,207...37,724,351
|
|
G |
Axl |
Axl receptor tyrosine kinase |
decreases response to substance |
ISO |
AXL protein results in decreased susceptibility to Adenosine Diphosphate |
CTD |
PMID:15733062 |
|
NCBI chr 1:90,392,864...90,424,123
|
|
G |
Cat |
catalase |
multiple interactions |
EXP |
CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] |
CTD |
PMID:16781456 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cd40lg |
CD40 ligand |
increases expression multiple interactions |
ISO |
Adenosine Diphosphate results in increased expression of CD40LG protein clopidogrel inhibits the reaction [Adenosine Diphosphate results in increased expression of CD40LG protein] |
CTD |
PMID:11297035 PMID:17043144 |
|
NCBI chr X:140,164,341...140,176,057
|
|
G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions |
ISO |
Adenosine Diphosphate binds to and results in decreased activity of CFTR protein; P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein] |
CTD |
PMID:15684079 |
|
NCBI chr 4:47,422,084...47,694,646
|
|
G |
Chordc1 |
cysteine and histidine rich domain containing 1 |
multiple interactions |
ISO |
Adenosine Diphosphate binds to and affects the folding of CHORDC1 protein; Adenosine Diphosphate promotes the reaction [CHORDC1 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein] |
CTD |
PMID:23184943 |
|
NCBI chr 8:15,374,356...15,398,436
|
|
G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
multiple interactions |
ISO |
CYP2C19 gene affects the susceptibility to [Adenosine Diphosphate co-treated with clopidogrel]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid] |
CTD |
PMID:16772608 PMID:18004210 PMID:18394438 |
|
NCBI chr 1:247,879,058...247,916,804
|
|
G |
Dtymk |
deoxythymidylate kinase |
multiple interactions |
ISO |
DTYMK protein binds to [N1-(4-bis(pivaloyloxymethyl)phosphinylbuten-2-yl)thymine co-treated with Adenosine Diphosphate] |
CTD |
PMID:21128666 |
|
NCBI chr 9:101,762,899...101,771,733
|
|
G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions |
ISO |
Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP1 protein]] |
CTD |
PMID:32941855 |
|
NCBI chr10:17,184,853...17,187,646
|
|
G |
Dusp6 |
dual specificity phosphatase 6 |
multiple interactions |
ISO |
Adenosine Diphosphate inhibits the reaction [Cesium-137 results in increased expression of DUSP6 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in decreased expression of DUSP6 protein]] |
CTD |
PMID:32941855 |
|
NCBI chr 7:35,979,502...35,983,834
|
|
G |
Epha4 |
Eph receptor A4 |
increases phosphorylation multiple interactions |
ISO |
Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein Benzoic Acid analog inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of EPHA4 protein] |
CTD |
PMID:22273509 |
|
NCBI chr 9:86,263,982...86,406,744
|
|
G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions decreases activity |
ISO |
Adenosine Diphosphate inhibits the reaction [ERN1 protein binds to ERN1 protein] Adenosine Diphosphate results in decreased activity of ERN1 protein |
CTD |
PMID:25164867 |
|
NCBI chr10:91,826,663...91,920,976
|
|
G |
F2 |
coagulation factor II, thrombin |
increases abundance multiple interactions |
ISO |
F2 protein results in increased abundance of Adenosine Diphosphate Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate]; resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Diphosphate] |
CTD |
PMID:15342215 |
|
NCBI chr 3:98,051,958...98,065,246
|
|
G |
Fga |
fibrinogen alpha chain |
multiple interactions increases secretion |
ISO |
Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein] |
CTD |
PMID:17303692 |
|
NCBI chr 2:170,672,169...170,679,572
|
|
G |
Fgb |
fibrinogen beta chain |
decreases secretion multiple interactions |
ISO |
Adenosine Diphosphate results in decreased secretion of FGB protein Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein] |
CTD |
PMID:17303692 |
|
NCBI chr 2:168,394,901...168,402,863
|
|
G |
Fgg |
fibrinogen gamma chain |
increases secretion multiple interactions |
ISO |
Adenosine Diphosphate results in increased secretion of FGG protein Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein] |
CTD |
PMID:17303692 |
|
NCBI chr 2:168,354,880...168,362,325
|
|
G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions |
ISO |
Adenosine Diphosphate inhibits the reaction [[GAPDH protein co-treated with NAD co-treated with Glyceraldehyde 3-Phosphate co-treated with Glutathione] results in increased reduction of sodium arsenite analog] |
CTD |
PMID:15788719 |
|
NCBI chr 4:157,962,312...157,967,158
|
|
G |
Gas6 |
growth arrest specific 6 |
increases response to substance |
ISO |
GAS6 protein results in increased susceptibility to Adenosine Diphosphate |
CTD |
PMID:15733062 |
|
NCBI chr16:82,747,676...82,778,090
|
|
G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of H2AX protein modified form]] |
CTD |
PMID:32941855 |
|
NCBI chr 8:53,568,718...53,570,072
|
|
G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
Adenosine Diphosphate binds to and affects the folding of HRAS protein |
CTD |
PMID:16388579 |
|
NCBI chr 1:205,712,625...205,729,406
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
ISO |
Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
|
NCBI chr 6:135,523,604...135,529,687
|
|
G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Adenosine Diphosphate] |
CTD |
PMID:27469509 |
|
NCBI chr 1:143,447,925...143,467,248
|
|
G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
Adenosine Diphosphate results in increased expression of IL6 protein MRS 2211 inhibits the reaction [Adenosine Diphosphate results in increased expression of IL6 protein] |
CTD |
PMID:24849676 |
|
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Itga2 |
integrin subunit alpha 2 |
multiple interactions |
ISO |
ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate] |
CTD |
PMID:16214444 |
|
NCBI chr 2:46,520,345...46,621,487
|
|
G |
Itga2b |
integrin subunit alpha 2b |
multiple interactions |
ISO |
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] |
CTD |
PMID:18404433 |
|
NCBI chr10:87,408,532...87,426,055
|
|
G |
Itgb1bp2 |
integrin subunit beta 1 binding protein 2 |
multiple interactions |
ISO |
Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to CHORDC1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]; Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to ITGB1BP2 protein]; Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:23184943 |
|
NCBI chr X:70,612,118...70,617,158
|
|
G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions |
ISO |
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of [ITGA2B protein binds to ITGB3 protein]]] |
CTD |
PMID:18404433 |
|
NCBI chr10:90,009,927...90,067,787
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
Adenosine Diphosphate results in increased phosphorylation of MAPK1 protein Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK1 protein]] |
CTD |
PMID:15034929 PMID:32941855 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Adenosine Diphosphate results in increased phosphorylation of MAPK3 protein Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased phosphorylation of MAPK3 protein]] |
CTD |
PMID:15034929 PMID:32941855 |
|
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions |
ISO |
Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:24466103 |
|
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
ISO |
Dicumarol inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:24466103 |
|
NCBI chr10:34,670,750...34,711,972
|
|
G |
Mapt |
microtubule-associated protein tau |
multiple interactions increases abundance |
ISO |
PF-06840003 inhibits the reaction [MAPT protein mutant form results in increased abundance of Adenosine Diphosphate] |
CTD |
PMID:39172838 |
|
NCBI chr10:89,638,618...89,736,108
|
|
G |
Mertk |
MER proto-oncogene, tyrosine kinase |
increases response to substance |
ISO |
MERTK protein results in increased susceptibility to Adenosine Diphosphate |
CTD |
PMID:15733062 |
|
NCBI chr 3:136,391,936...136,498,366
|
|
G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate] |
CTD |
PMID:11498454 |
|
NCBI chr10:64,313,335...64,349,221
|
|
G |
Nt5e |
5' nucleotidase, ecto |
decreases activity |
ISO |
Adenosine Diphosphate analog results in decreased activity of NT5E protein |
CTD |
PMID:18404487 |
|
NCBI chr 8:98,150,925...98,195,646
|
|
G |
P2ry12 |
purinergic receptor P2Y12 |
affects response to substance increases response to substance multiple interactions |
ISO EXP |
P2RY12 gene polymorphism affects the susceptibility to Adenosine Diphosphate; P2RY12 protein affects the susceptibility to Adenosine Diphosphate P2RY12 protein results in increased susceptibility to Adenosine Diphosphate Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate] P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein] |
CTD |
PMID:11196645 PMID:11413167 PMID:18404433 PMID:23849096 |
|
NCBI chr 2:143,481,468...143,523,340
|
|
G |
Pdgfb |
platelet derived growth factor subunit B |
increases secretion multiple interactions |
ISO |
Adenosine Diphosphate results in increased secretion of PDGFB protein Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein] |
CTD |
PMID:17303692 |
|
NCBI chr 7:113,419,882...113,438,343
|
|
G |
Pf4 |
platelet factor 4 |
increases secretion multiple interactions |
ISO |
Adenosine Diphosphate results in increased secretion of PF4 protein silidianin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; Silybin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein]; silychristin inhibits the reaction [Adenosine Diphosphate results in increased secretion of PF4 protein] |
CTD |
PMID:19428933 PMID:29439388 |
|
NCBI chr14:17,582,477...17,583,392
|
|
G |
Pfkm |
phosphofructokinase, muscle |
multiple interactions |
ISO |
Adenosine Diphosphate inhibits the reaction [resveratrol results in decreased activity of PFKM protein] |
CTD |
PMID:23454376 |
|
NCBI chr 7:131,100,684...131,138,250
|
|
G |
Pgp |
phosphoglycolate phosphatase |
decreases phosphorylation |
ISO |
PGP protein results in decreased phosphorylation of Adenosine Diphosphate |
CTD |
PMID:24338473 |
|
NCBI chr10:13,999,782...14,002,408
|
|
G |
Ppbp |
pro-platelet basic protein |
increases secretion |
ISO |
Adenosine Diphosphate results in increased secretion of PPBP protein |
CTD |
PMID:19428933 |
|
NCBI chr14:17,586,495...17,587,299
|
|
G |
Ppp5c |
protein phosphatase 5, catalytic subunit |
multiple interactions |
ISO |
Adenosine Diphosphate binds to and affects the folding of PPP5C protein |
CTD |
PMID:23184943 |
|
NCBI chr 1:86,818,297...86,842,505
|
|
G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Adenosine Diphosphate] |
CTD |
PMID:39172838 |
|
NCBI chr 6:109,054,160...109,106,191
|
|
G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
increases glutathionylation multiple interactions |
EXP |
Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein CAT protein inhibits the reaction [Adenosine Diphosphate results in increased glutathionylation of PTPN1 protein] |
CTD |
PMID:16781456 |
|
NCBI chr 3:156,638,811...156,687,503
|
|
G |
Selp |
selectin P |
multiple interactions increases expression |
ISO |
cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; CYP2C19 gene SNP affects the reaction [Adenosine Diphosphate results in increased expression of SELP protein]; Heparin promotes the reaction [Adenosine Diphosphate affects the localization of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate promotes the reaction [cangrelor inhibits the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]]; P2RY12 protein affects the reaction [Adenosine Diphosphate analog results in increased expression of SELP protein]; Quercetin inhibits the reaction [Adenosine Diphosphate results in increased expression of SELP protein] |
CTD |
PMID:9740346 PMID:18394438 PMID:18404433 PMID:23249183 |
|
NCBI chr13:76,476,229...76,511,846
|
|
G |
Sirt3 |
sirtuin 3 |
decreases abundance |
ISO |
SIRT3 protein results in decreased abundance of Adenosine Diphosphate |
CTD |
PMID:23166782 |
|
NCBI chr 1:195,942,066...195,964,472
|
|
G |
Taldo1 |
transaldolase 1 |
increases abundance |
ISO |
TALDO1 gene mutant form results in increased abundance of Adenosine Diphosphate |
CTD |
PMID:19436114 |
|
NCBI chr 1:205,923,196...205,933,526
|
|
G |
Thbs1 |
thrombospondin 1 |
increases secretion |
ISO |
Adenosine Diphosphate results in increased secretion of THBS1 protein |
CTD |
PMID:17303692 |
|
NCBI chr 3:125,510,250...125,525,402
|
|
G |
Tp53bp1 |
tumor protein p53 binding protein 1 |
multiple interactions |
ISO |
Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]; Anthraquinones analog inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]]; U 0126 inhibits the reaction [Adenosine Diphosphate promotes the reaction [Cesium-137 results in increased expression of and affects the localization of TP53BP1 protein]] |
CTD |
PMID:32941855 |
|
NCBI chr 3:108,166,574...108,270,229
|
|
G |
Tyro3 |
TYRO3 protein tyrosine kinase |
increases response to substance |
ISO |
TYRO3 protein results in increased susceptibility to Adenosine Diphosphate |
CTD |
PMID:15733062 |
|
NCBI chr 3:127,231,468...127,254,806
|
|
G |
Vasp |
vasodilator-stimulated phosphoprotein |
increases phosphorylation multiple interactions |
ISO |
Adenosine Diphosphate results in increased phosphorylation of VASP protein N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Adenosine Diphosphate results in increased phosphorylation of VASP protein] |
CTD |
PMID:25329809 |
|
NCBI chr 1:88,038,026...88,053,783
|
|
|
G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
affects binding |
ISO |
acetoacetyl CoA binds to HSD17B2 protein |
CTD |
PMID:25526675 |
|
NCBI chr19:45,753,576...45,825,203
|
|
|
G |
Acly |
ATP citrate lyase |
increases abundance affects abundance |
ISO |
ACLY protein results in increased abundance of Acetyl Coenzyme A ACLY protein affects the abundance of Acetyl Coenzyme A |
CTD |
PMID:28077572 PMID:36933457 |
|
NCBI chr10:85,412,045...85,464,253
|
|
G |
App |
amyloid beta precursor protein |
affects localization increases secretion multiple interactions |
ISO |
APP protein affects the localization of Acetyl Coenzyme A Acetyl Coenzyme A results in increased secretion of APP protein modified form Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form] IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] |
CTD |
PMID:16122837 PMID:22906069 |
|
NCBI chr11:37,506,207...37,724,351
|
|
G |
Crat |
carnitine O-acetyltransferase |
decreases activity |
EXP |
Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein |
CTD |
PMID:8075222 |
|
NCBI chr 3:13,675,684...13,689,282
|
|
G |
Ercc6 |
ERCC excision repair 6, chromatin remodeling factor |
decreases abundance multiple interactions |
ISO |
ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A 3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A] |
CTD |
PMID:25440059 |
|
NCBI chr16:7,771,311...7,841,895
|
|
G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Fluoxetine results in decreased expression of G6PC1 protein] which results in increased abundance of Acetyl Coenzyme A |
CTD |
PMID:33179799 |
|
NCBI chr10:86,307,400...86,318,766
|
|
G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] |
CTD |
PMID:16122837 |
|
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Kat2b |
lysine acetyltransferase 2B |
affects binding |
ISO |
Acetyl Coenzyme A binds to KAT2B protein |
CTD |
PMID:28077572 |
|
NCBI chr 9:6,799,101...6,903,616
|
|
G |
Metrnl |
meteorin-like, glial cell differentiation regulator |
multiple interactions |
ISO |
METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] |
CTD |
PMID:30213948 |
|
NCBI chr10:106,963,880...106,977,875
|
|
G |
Nat1 |
N-acetyltransferase 1 |
multiple interactions affects binding |
ISO |
[NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein] Acetyl Coenzyme A binds to NAT1 protein |
CTD |
PMID:20545351 PMID:22835378 |
|
NCBI chr16:22,218,217...22,238,516
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G |
Nat2 |
N-acetyltransferase 2 |
multiple interactions |
ISO |
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] |
CTD |
PMID:20545351 |
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NCBI chr16:26,974,874...27,005,191
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone |
CTD |
PMID:20545351 |
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NCBI chr19:52,205,374...52,220,267
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
increases abundance |
ISO |
ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A |
CTD |
PMID:25125611 |
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NCBI chr 1:194,895,036...194,903,863
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G |
Hibch |
3-hydroxyisobutyryl-CoA hydrolase |
increases abundance |
ISO |
HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A |
CTD |
PMID:25125611 |
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NCBI chr 9:48,590,097...48,669,896
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G |
Adprh |
ADP-ribosylarginine hydrolase |
increases hydrolysis |
ISO |
ADPRH protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite |
CTD |
PMID:21498885 |
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NCBI chr11:62,299,831...62,306,170
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G |
Adprs |
ADP-ribosylserine hydrolase |
increases hydrolysis multiple interactions |
ISO |
ADPRS protein results in increased hydrolysis of Adenosine Diphosphate Ribose metabolite Adenosine Diphosphate Ribose inhibits the reaction [ADPRS protein results in increased hydrolysis of O-Acetyl-ADP-Ribose] |
CTD |
PMID:21498885 |
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NCBI chr 5:138,614,022...138,619,296
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G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions |
ISO |
NOS1 protein affects the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased ribosylation of Adenosine Diphosphate Ribose] |
CTD |
PMID:10318960 |
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NCBI chr12:44,276,011...44,456,371
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G |
Trpm2 |
transient receptor potential cation channel, subfamily M, member 2 |
multiple interactions increases activity |
EXP ISO |
Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]; Clotrimazole inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]]; Flufenamic Acid inhibits the reaction [Adenosine Diphosphate Ribose promotes the reaction [TRPM2 protein results in increased transport of Calcium]] Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein 2-aminoethoxydiphenyl borate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]]; Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Copper Sulfate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Eicosapentaenoic Acid promotes the reaction [Cisplatin promotes the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]]; ferrous chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; lead nitrate inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Mercuric Chloride inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Miconazole inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; Selenium Oxides inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein] 4-amylcinnamoylanthranilic acid inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; 4-amylcinnamoylanthranilic acid inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; [Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein; Glutathione inhibits the reaction [[Buthionine Sulfoximine co-treated with Adenosine Diphosphate Ribose] results in increased activity of TRPM2 protein]; Glutathione inhibits the reaction [Adenosine Diphosphate Ribose results in increased activity of TRPM2 protein]; TRPM2 protein promotes the reaction [Adenosine Diphosphate Ribose results in increased uptake of Calcium] |
CTD |
PMID:18204483 PMID:20878536 PMID:21900507 PMID:22750002 PMID:33309544 PMID:35395232 More...
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NCBI chr20:10,703,568...10,753,189
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Kat2b |
lysine acetyltransferase 2B |
affects binding |
ISO |
butyryl-coenzyme A binds to KAT2B protein |
CTD |
PMID:28077572 |
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NCBI chr 9:6,799,101...6,903,616
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G |
Acot8 |
acyl-CoA thioesterase 8 |
affects hydrolysis |
ISO |
ACOT8 protein affects the hydrolysis of Coenzyme A analog |
CTD |
PMID:16141203 |
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NCBI chr 3:153,531,192...153,542,851
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G |
Kat2b |
lysine acetyltransferase 2B |
affects binding |
ISO |
Coenzyme A binds to KAT2B protein |
CTD |
PMID:28077572 |
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NCBI chr 9:6,799,101...6,903,616
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G |
Cd38 |
CD38 molecule |
decreases abundance |
ISO |
CD38 gene mutant form results in decreased abundance of Cyclic ADP-Ribose |
CTD |
PMID:23343681 |
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NCBI chr14:71,384,532...71,424,794
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G |
Homer1 |
homer scaffold protein 1 |
multiple interactions |
EXP |
HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 |
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NCBI chr 2:26,279,012...26,388,279
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G |
Ryr2 |
ryanodine receptor 2 |
multiple interactions |
EXP |
HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] |
CTD |
PMID:12887973 |
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NCBI chr17:58,389,925...58,975,641
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein |
CTD |
PMID:25526675 |
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NCBI chr 5:74,443,933...74,479,104
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[decanoyl-coenzyme A co-treated with NADP] binds to PECR protein |
CTD |
PMID:25526675 |
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NCBI chr 9:73,897,877...73,926,511
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G |
Acot4 |
acyl-CoA thioesterase 4 |
affects hydrolysis |
ISO |
ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A |
CTD |
PMID:16141203 |
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NCBI chr 6:103,668,699...103,674,037
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G |
Acot8 |
acyl-CoA thioesterase 8 |
affects hydrolysis |
ISO |
ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A |
CTD |
PMID:16141203 |
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NCBI chr 3:153,531,192...153,542,851
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein |
CTD |
PMID:25526675 |
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NCBI chr 9:73,897,877...73,926,511
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G |
Kat2b |
lysine acetyltransferase 2B |
affects binding |
ISO |
isobutyryl-coenzyme A binds to KAT2B protein |
CTD |
PMID:28077572 |
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NCBI chr 9:6,799,101...6,903,616
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
lauroyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[lauroyl-coenzyme A co-treated with NADP] binds to HSDL2 protein |
CTD |
PMID:25526675 |
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NCBI chr 5:74,443,933...74,479,104
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[lauroyl-coenzyme A co-treated with NADP] binds to PECR protein |
CTD |
PMID:25526675 |
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NCBI chr 9:73,897,877...73,926,511
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G |
Mlycd |
malonyl-CoA decarboxylase |
multiple interactions |
ISO |
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] |
CTD |
PMID:14641110 |
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NCBI chr19:64,356,582...64,372,447
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
PPARA protein promotes the reaction [MLYCD protein results in decreased abundance of Malonyl Coenzyme A] |
CTD |
PMID:14641110 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
increases abundance |
ISO |
ECHS1 gene mutant form results in increased abundance of methacrylyl-coenzyme A |
CTD |
PMID:25125611 |
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NCBI chr 1:194,895,036...194,903,863
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G |
Hibch |
3-hydroxyisobutyryl-CoA hydrolase |
increases abundance |
ISO |
HIBCH gene mutant form results in increased abundance of methacrylyl-coenzyme A |
CTD |
PMID:25125611 |
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NCBI chr 9:48,590,097...48,669,896
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G |
Dbi |
diazepam binding inhibitor |
affects binding |
ISO |
S-tetradecanoyl-coenzyme A binds to DBI protein |
CTD |
PMID:17044054 |
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NCBI chr13:33,794,231...33,802,632
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
S-tetradecanoyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
oleoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
oleoyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
oleoyl-coenzyme A binds to and results in increased activity of PPARG protein |
CTD |
PMID:11139385 |
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NCBI chr 4:150,095,743...150,221,104
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases metabolic processing multiple interactions |
ISO |
ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A [ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide; benz(a)anthracene promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Dehydroepiandrosterone promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide]; Tetrachlorodibenzodioxin promotes the reaction [[ACOX1 protein results in increased metabolism of Palmitoyl Coenzyme A] which results in increased chemical synthesis of Hydrogen Peroxide] |
CTD |
PMID:10497882 |
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NCBI chr10:101,905,083...101,930,136
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G |
Ces1d |
carboxylesterase 1D |
increases hydrolysis |
EXP |
CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A |
CTD |
PMID:8611161 |
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NCBI chr19:30,046,494...30,085,039
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions |
EXP |
valproyl-coenzyme A inhibits the reaction [CPT1A protein results in increased metabolism of Palmitoyl Coenzyme A] |
CTD |
PMID:19854160 |
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NCBI chr 1:209,993,881...210,056,329
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
DGAT1 protein results in increased metabolism of [Palmitoyl Coenzyme A co-treated with Vitamin A] |
CTD |
PMID:16214399 |
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NCBI chr 7:110,104,514...110,119,091
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression |
ISO |
Palmitoyl Coenzyme A results in decreased expression of HNF4A mRNA; Palmitoyl Coenzyme A results in decreased expression of HNF4A protein |
CTD |
PMID:17992261 |
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NCBI chr 3:152,186,787...152,248,320
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in increased activity of PPARA protein Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atorvastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Atropine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Enalapril inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gamma-Aminobutyric Acid inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; gedunin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]; Pravastatin promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Pyrazinamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Saccharin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; salicylamide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolazoline inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Tolmetin inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] |
CTD |
PMID:11139385 PMID:18812576 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
Palmitoyl Coenzyme A binds to and results in increased activity of PPARG protein |
CTD |
PMID:11139385 |
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NCBI chr 4:150,095,743...150,221,104
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G |
Shbg |
sex hormone binding globulin |
decreases expression |
ISO |
Palmitoyl Coenzyme A results in decreased expression of SHBG mRNA; Palmitoyl Coenzyme A results in decreased expression of SHBG protein |
CTD |
PMID:17992261 |
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NCBI chr10:54,332,939...54,350,409
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
stearoyl-coenzyme A binds to and results in decreased activity of GSTA1 protein |
CTD |
PMID:10542059 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
stearoyl-coenzyme A binds to and results in increased activity of PPARA protein |
CTD |
PMID:11139385 |
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NCBI chr 7:118,712,261...118,780,723
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
stearoyl-coenzyme A binds to and results in increased activity of PPARG protein |
CTD |
PMID:11139385 |
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NCBI chr 4:150,095,743...150,221,104
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G |
Acot4 |
acyl-CoA thioesterase 4 |
affects hydrolysis |
ISO |
ACOT4 protein affects the hydrolysis of succinyl-coenzyme A |
CTD |
PMID:16141203 |
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NCBI chr 6:103,668,699...103,674,037
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