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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alatrofloxacin
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Accession:CHEBI:135829 term browser browse the term
Synonyms:related_synonym: Formula=C26H25F3N6O5;   InChI=1S/C26H25F3N6O5/c1-10(30)24(37)31-11(2)25(38)32-20-14-7-34(8-15(14)20)23-18(29)6-13-21(36)16(26(39)40)9-35(22(13)33-23)19-4-3-12(27)5-17(19)28/h3-6,9-11,14-15,20H,7-8,30H2,1-2H3,(H,31,37)(H,32,38)(H,39,40)/t10-,11-,14-,15+,20+/m0/s1;   InChIKey=UUZPPAMZDFLUHD-VUJLHGSVSA-N;   SMILES=O=C1C=2C(N(C=C1C(O)=O)C3=C(F)C=C(C=C3)F)=NC(=C(C2)F)N4C[C@]5([C@@](C4)([C@@H]5NC([C@@H](NC([C@H](C)N)=O)C)=O)[H])[H];   alatrofloxacin mesilate;   alatrofloxacin mesylate
 xref: CAS:146961-76-4;   Drug_Central:102
 xref_mesh: MESH:C106856


show annotations for term's descendants           Sort by:
alatrofloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco2 aconitase 2 decreases expression
multiple interactions
decreases activity		 ISO alatrofloxacin results in decreased expression of ACO2 mRNA
SOD2 protein affects the susceptibility to [alatrofloxacin results in decreased activity of ACO2 protein]; SOD2 protein affects the susceptibility to [alatrofloxacin results in decreased expression of ACO2 mRNA]		 CTD PMID:20655887 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO alatrofloxacin results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Il24 interleukin 24 increases expression ISO alatrofloxacin results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO alatrofloxacin results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO alatrofloxacin results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO SOD2 protein affects the susceptibility to [alatrofloxacin results in decreased activity of ACO2 protein]; SOD2 protein affects the susceptibility to [alatrofloxacin results in decreased expression of ACO2 mRNA]; SOD2 protein affects the susceptibility to [alatrofloxacin results in increased abundance of Peroxynitrous Acid] CTD PMID:20655887 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      group 19765
        organic group 18936
          amino-acid residue 11122
            peptide 11122
              alatrofloxacin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      carboacyl group 17677
                                        univalent carboacyl group 17677
                                          carbamoyl group 17526
                                            carboxamide 17526
                                              peptide 11122
                                                alatrofloxacin 6
paths to the root