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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:milnacipran
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Accession:CHEBI:135005 term browser browse the term
Synonyms:related_synonym: Formula=C15H22N2O;   InChI=1S/C15H22N2O/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12/h5-9,13H,3-4,10-11,16H2,1-2H3;   InChIKey=GJJFMKBJSRMPLA-UHFFFAOYSA-N;   SMILES=C1=CC=CC=C1C2(C(N(CC)CC)=O)CC2CN;   midalcipran;   milnacipran HCl;   milnacipran hydrochloride
 xref: CAS:92623-85-3;   Drug_Central:1808
 xref_mesh: MESH:C048107


show annotations for term's descendants           Sort by:
milnacipran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Milnacipran results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Hcrtr1 hypocretin receptor 1 increases expression ISO milnacipran results in increased expression of HCRTR1 mRNA CTD PMID:21157932 NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Hcrtr2 hypocretin receptor 2 increases expression ISO milnacipran results in increased expression of HCRTR2 mRNA CTD PMID:21157932 NCBI chr 8:76,989,834...77,105,953
Ensembl chr 8:76,989,834...77,105,893 		JBrowse link
G Hdc histidine decarboxylase increases expression ISO milnacipran results in increased expression of HDC mRNA CTD PMID:21157932 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hrh1 histamine receptor H 1 increases expression ISO milnacipran results in increased expression of HRH1 mRNA CTD PMID:21157932 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    chemical entity 19842
      atom 19842
        nonmetal atom 19780
          nitrogen atom 18958
            nitrogen molecular entity 18958
              organonitrogen compound 18808
                carboxamide 17554
                  acetamides 14636
                    milnacipran 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            heteroorganic entity 19486
                              organochalcogen compound 19249
                                organooxygen compound 19167
                                  carbon oxoacid 18634
                                    carboxylic acid 18631
                                      carboacyl group 17703
                                        univalent carboacyl group 17703
                                          carbamoyl group 17554
                                            carboxamide 17554
                                              acetamides 14636
                                                milnacipran 5
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