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flurotyl - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:flurotyl
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Accession:CHEBI:134824 term browser browse the term
Synonyms:related_synonym: Formula=C4H4F6O;   InChI=1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2;   InChIKey=KGPPDNUWZNWPSI-UHFFFAOYSA-N;   SMILES=FC(F)(F)COCC(F)(F)F;   fluorothyl;   fluroethyl;   flurothyl;   hexafluorodiethyl ether
 xref: CAS:333-36-8;   Drug_Central:3241
 xref_mesh: MESH:D005481


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flurotyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression EXP Flurothyl results in decreased expression of CAMK2A mRNA CTD PMID:19059322 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr10:27,096,731...27,152,563
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr14:36,434,339...36,917,920
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr10:26,876,926...26,965,523
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Flurothyl inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Plppr4 phospholipid phosphatase related 4 increases expression EXP Flurothyl results in increased expression of PLPPR4 protein CTD PMID:20167268 NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302
JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression EXP Flurothyl results in decreased expression of SLC30A1 mRNA CTD PMID:19059322 PMID:20167268 NCBI chr13:106,022,019...106,025,892
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc30a3 solute carrier family 30 member 3 affects expression EXP Flurothyl affects the expression of SLC30A3 mRNA CTD PMID:20167268 NCBI chr 6:30,984,241...31,004,689
Ensembl chr 6:25,275,528...25,284,720
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    chemical entity 19885
      atom 19885
        nonmetal atom 19809
          oxygen atom 19551
            oxygen molecular entity 19551
              organooxygen compound 19197
                ether 17318
                  flurotyl 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  ether 17318
                                    flurotyl 8
paths to the root