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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:brexpiprazole
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Accession:CHEBI:134716 term browser browse the term
Synonyms:related_synonym: Formula=C25H27N3O2S;   InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29);   InChIKey=ZKIAIYBUSXZPLP-UHFFFAOYSA-N;   OPC-34712;   SMILES=C1CN(CCN1CCCCOC2=CC3=C(C=C2)C=CC(N3)=O)C4=C5C(=CC=C4)SC=C5;   rexulti
 xref: CAS:913611-97-9;   Drug_Central:5014
 xref_mesh: MESH:C000591922


show annotations for term's descendants           Sort by:
brexpiprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO brexpiprazole results in decreased expression of ACACA mRNA; brexpiprazole results in decreased expression of ACACA protein CTD PMID:37347510 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acly ATP citrate lyase decreases expression ISO brexpiprazole results in decreased expression of ACLY mRNA; brexpiprazole results in decreased expression of ACLY protein CTD PMID:37347510 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO brexpiprazole results in decreased expression of CCND1 protein CTD PMID:37347510 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Fasn fatty acid synthase decreases expression ISO brexpiprazole results in decreased expression of FASN mRNA; brexpiprazole results in decreased expression of FASN protein CTD PMID:37347510 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO brexpiprazole results in decreased expression of MKI67 protein CTD PMID:37347510 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO brexpiprazole results in decreased expression of PCNA protein CTD PMID:37347510 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO brexpiprazole results in decreased expression of SCD mRNA; brexpiprazole results in decreased expression of SCD protein CTD PMID:37347510 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO brexpiprazole results in decreased expression of SREBF1 mRNA; brexpiprazole results in decreased expression of SREBF1 protein CTD PMID:37347510 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      application 19703
        NMR chemical shift reference compound 18081
          ammonia 17860
            organic amino compound 17860
              aromatic amine 15475
                N-arylpiperazine 3439
                  brexpiprazole 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    main group molecular entity 19806
                      s-block molecular entity 19641
                        hydrogen molecular entity 19622
                          hydrides 19150
                            inorganic hydride 18152
                              pnictogen hydride 18164
                                nitrogen hydride 18055
                                  azane 17882
                                    ammonia 17860
                                      organic amino compound 17860
                                        tertiary amino compound 10153
                                          N-arylpiperazine 3439
                                            brexpiprazole 8
paths to the root