Acaca (acetyl-CoA carboxylase alpha) - Rat Genome Database

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Gene: Acaca (acetyl-CoA carboxylase alpha) Rattus norvegicus
Analyze
Symbol: Acaca
Name: acetyl-CoA carboxylase alpha
RGD ID: 621248
Description: Enables acetyl-CoA carboxylase activity and biotin binding activity. Involved in fatty acid biosynthetic process; response to nutrient; and response to xenobiotic stimulus. Predicted to be located in actin cytoskeleton; cytosol; and fibrillar center. Predicted to be active in mitochondrion. Used to study steatotic liver disease. Biomarker of metabolic dysfunction-associated steatohepatitis and metabolic dysfunction-associated steatotic liver disease. Orthologous to human ACACA (acetyl-CoA carboxylase alpha); PARTICIPATES IN fatty acid biosynthetic pathway; Leigh disease pathway; malonic aciduria pathway; INTERACTS WITH (R)-carnitine; (S)-nicotine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Acac; ACC-alpha; ACC1; acetyl-CoA carboxylase 1; acetyl-coenzyme A carboxylase; acetyl-Coenzyme A carboxylase alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81069,511,627 - 69,773,888 (+)NCBIGRCr8
mRatBN7.21069,014,261 - 69,276,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1069,014,170 - 69,276,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1073,702,781 - 73,894,445 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01073,207,804 - 73,399,466 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01068,672,215 - 68,863,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01071,519,392 - 71,719,910 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1071,536,533 - 71,719,910 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01071,431,885 - 71,630,271 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,483,772 - 72,677,134 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11072,498,141 - 72,691,504 (+)NCBI
Celera1068,011,070 - 68,201,435 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Object Symbol
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Original Reference(s)
AcacaRatatherosclerosis treatmentISOAcaca (Mus musculus)401842381 RGD 
AcacaRatHypertriglyceridemia treatmentIEP 329955565 RGD 
AcacaRatInsulin Resistance  IDA 1625727 RGD 
AcacaRatInsulin Resistance treatmentIEP 329955565 RGD 
AcacaRatmetabolic dysfunction-associated steatohepatitis treatmentIEP 401799674 RGD 
AcacaRatmetabolic dysfunction-associated steatotic liver disease treatmentIEP 329955565 RGD 
AcacaRatMetabolic Syndrome amelioratesIEP 401799622 RGD 
AcacaRatMetabolic Syndrome  ISOAcaca (Mus musculus)329333017mRNA:increased expression:liver (mouse)RGD 
AcacaRatsteatotic liver disease  IDA 1625727 RGD 
1 to 9 of 9 rows
Object Symbol
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Original Reference(s)
AcacaRatAcetyl-Coa Carboxylase Deficiency  ISOACACA (Homo sapiens)8554872ClinVar more ...ClinVarPMID:15333468 more ...
AcacaRatautism spectrum disorder  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: Autism spectrum disorderClinVarPMID:21844811 more ...
AcacaRatautistic disorder  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
AcacaRatchromosome 17q12 deletion syndrome  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 17q12 deletion syndromeClinVarPMID:17924346 more ...
AcacaRathereditary breast ovarian cancer syndrome  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary breast ovarian cancer syndromeClinVarPMID:25741868
AcacaRathyperphosphatasia with impaired intellectual development syndrome 5  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESIS DEFECT 11ClinVarPMID:12148114 more ...
AcacaRatNeurodevelopmental Disorders  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
AcacaRatschizophrenia  ISOACACA (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311
Object Symbol
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Original Reference(s)
AcacaRatAcetyl-Coa Carboxylase Deficiency  ISOACACA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
AcacaRatcongestive heart failure  ISOACACA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26670611
AcacaRathepatocellular carcinoma  ISOACACA (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21147110
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Original Reference(s)
AcacaRatAcetyl-Coa Carboxylase Deficiency  ISOACACA (Homo sapiens)7240710 OMIM 

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Original Reference(s)
AcacaRat(+)-beta-thujone multiple interactionsISOACACA (Homo sapiens)6480464[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNACTDPMID:38000518
AcacaRat(+)-pinoresinol multiple interactionsISOACACA (Homo sapiens)6480464[loliolide co-treated with pinoresinol] results in decreased expression of ACACA proteinCTDPMID:31610126
AcacaRat(+)-pinoresinol decreases expressionISOACACA (Homo sapiens)6480464pinoresinol results in decreased expression of ACACA proteinCTDPMID:31610126
AcacaRat(-)-epigallocatechin 3-gallate multiple interactionsISOAcaca (Mus musculus)6480464epigallocatechin gallate inhibits the reaction [1 and 3-dichloro-2-propanol results in decreased phosphorylation of ACACA protein]CTDPMID:30092300
AcacaRat(1->4)-beta-D-glucan multiple interactionsISOAcaca (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ACACA mRNACTDPMID:36331819
AcacaRat(R)-camphor multiple interactionsISOACACA (Homo sapiens)6480464[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNACTDPMID:38000518
AcacaRat(R)-carnitine decreases expressionEXP 6480464Carnitine results in decreased expression of ACACA proteinCTDPMID:25669660
AcacaRat(R)-linalyl acetate multiple interactionsISOACACA (Homo sapiens)6480464[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNACTDPMID:38000518
AcacaRat(S)-nicotine increases expressionEXP 6480464Nicotine results in increased expression of ACACA mRNACTDPMID:24368177 and PMID:29155039
AcacaRat1,2-dichloroethane decreases expressionISOAcaca (Mus musculus)6480464ethylene dichloride results in decreased expression of ACACA mRNACTDPMID:28189721 and PMID:28960355
AcacaRat1,2-dimethylhydrazine affects expressionISOAcaca (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of ACACA mRNACTDPMID:22206623
AcacaRat1,3-dichloropropan-2-ol multiple interactionsISOAcaca (Mus musculus)6480464epigallocatechin gallate inhibits the reaction [1 and 3-dichloro-2-propanol results in decreased phosphorylation of ACACA protein]CTDPMID:30092300
AcacaRat1,3-dichloropropan-2-ol decreases phosphorylationISOAcaca (Mus musculus)64804641 and 3-dichloro-2-propanol results in decreased phosphorylation of ACACA proteinCTDPMID:30092300
AcacaRat1,8-cineole multiple interactionsISOACACA (Homo sapiens)6480464[beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in decreased expression of ACACA mRNACTDPMID:38000518
AcacaRat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of ACACA mRNACTDPMID:30723492
AcacaRat17alpha-ethynylestradiol multiple interactionsISOAcaca (Mus musculus)6480464[lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of ACACA mRNACTDPMID:24440342
AcacaRat17alpha-ethynylestradiol increases phosphorylationEXP 6480464Ethinyl Estradiol results in increased phosphorylation of ACACA proteinCTDPMID:27090119
AcacaRat17beta-estradiol increases expressionISOACACA (Homo sapiens)6480464Estradiol results in increased expression of ACACA mRNACTDPMID:23019147
AcacaRat17beta-estradiol decreases expressionISOAcaca (Mus musculus)6480464Estradiol results in decreased expression of ACACA mRNACTDPMID:39298647
AcacaRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of ACACA mRNACTDPMID:26164745

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Biological Process
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Original Reference(s)
AcacaRatacetyl-CoA metabolic process involved_inIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatacetyl-CoA metabolic process involved_inISOAcaca (Mus musculus)1624291 PMID:20952656RGDPMID:20952656
AcacaRatcarboxylic acid metabolic process involved_inIEAARBA:ARBA000272761600115GO_REF:0000117UniProtGO_REF:0000117
AcacaRatcellular response to prostaglandin E stimulus acts_upstream_of_or_withinISOAcaca (Mus musculus)1624291 PMID:23479225RGDPMID:23479225
AcacaRatcellular response to prostaglandin E stimulus acts_upstream_of_or_withinIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatfatty acid biosynthetic process  IDA 2317316 RGD 
AcacaRatfatty acid biosynthetic process involved_inIBAMGI:108451 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
AcacaRatfatty acid biosynthetic process involved_inISOAcaca (Mus musculus)1624291 PMID:20952656RGDPMID:20952656
AcacaRatfatty acid biosynthetic process involved_inIEAInterPro:IPR0135371600115GO_REF:0000002InterProGO_REF:0000002
AcacaRatfatty acid biosynthetic process involved_inIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatfatty acid biosynthetic process involved_inIEAUniProtKB-KW:KW-02751600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatfatty acid metabolic process involved_inIEAUniProtKB-KW:KW-02761600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatlipid biosynthetic process involved_inISOAcaca (Mus musculus)1624291MGI:2140940 more ...RGDPMID:16717184 and PMID:17210641
AcacaRatlipid biosynthetic process involved_inIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatlipid homeostasis acts_upstream_of_or_withinIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatlipid homeostasis acts_upstream_of_or_withinISOAcaca (Mus musculus)1624291MGI:3700954 PMID:17210641RGDPMID:17210641
AcacaRatlipid metabolic process involved_inIEAUniProtKB-KW:KW-04431600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatlipid metabolic process acts_upstream_of_or_withinISOAcaca (Mus musculus)1624291MGI:3700954 PMID:17210641RGDPMID:17210641
AcacaRatlipid metabolic process acts_upstream_of_or_withinIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatmalonyl-CoA biosynthetic process involved_inIEAUniPathway:UPA006551600115GO_REF:0000041UniProtGO_REF:0000041
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Cellular Component
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Original Reference(s)
AcacaRatactin cytoskeleton located_inIEAUniProtKB:Q13085 and ensembl:ENSP000004833001600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatactin cytoskeleton located_inISOACACA (Homo sapiens) more ...1624291 RGDGO_REF:0000052
AcacaRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
AcacaRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatcytosol located_inIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatcytosol located_inISOAcaca (Mus musculus)1624291 PMID:20952656RGDPMID:20952656
AcacaRatcytosol located_inISSUniProtKB:Q5SWU91600115GO_REF:0000024UniProtGO_REF:0000024
AcacaRatcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
AcacaRatcytosol is_active_inISOAcaca (Mus musculus)1624291MGI:2140940 PMID:16717184 more ...RGDPMID:16717184 more ...
AcacaRatcytosol located_inISOACACA (Homo sapiens) more ...1624291 RGDGO_REF:0000052
AcacaRatcytosol located_inIEAUniProtKB:Q13085 and ensembl:ENSP000004833001600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatfibrillar center located_inIEAUniProtKB:Q13085 and ensembl:ENSP000004833001600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatfibrillar center located_inISOACACA (Homo sapiens) more ...1624291 RGDGO_REF:0000052
AcacaRatmitochondrion is_active_inIBAMGI:2140940 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
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Molecular Function
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Original Reference(s)
AcacaRatacetyl-CoA carboxylase activity  IDA 2317316 RGD 
AcacaRatacetyl-CoA carboxylase activity enablesIEAUniProtKB:Q5SWU9 and ensembl:ENSMUSP000000994901600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatacetyl-CoA carboxylase activity enablesIBAMGI:108451 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
AcacaRatacetyl-CoA carboxylase activity enablesIEARHEA:113081600115GO_REF:0000116RHEAGO_REF:0000116
AcacaRatacetyl-CoA carboxylase activity enablesIEAInterPro:IPR013537 and InterPro:IPR0490761600115GO_REF:0000002InterProGO_REF:0000002
AcacaRatacetyl-CoA carboxylase activity enablesIEAUniProtKB:Q13085 and ensembl:ENSP000004833001600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatacetyl-CoA carboxylase activity enablesIEAARBA:ARBA000268631600115GO_REF:0000117UniProtGO_REF:0000117
AcacaRatacetyl-CoA carboxylase activity enablesISOACACA (Homo sapiens)1624291 PMID:20457939 more ...RGDPMID:20457939 more ...
AcacaRatacetyl-CoA carboxylase activity enablesIEAEC:6.4.1.21600115GO_REF:0000003UniProtGO_REF:0000003
AcacaRatacetyl-CoA carboxylase activity enablesIDA 10047183PMID:21569266CACAO 
AcacaRatacetyl-CoA carboxylase activity enablesISOAcaca (Mus musculus)1624291MGI:2140940 more ...RGDPMID:16717184 more ...
AcacaRatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatATP binding enablesIEAInterPro:IPR005479 more ...1600115GO_REF:0000002InterProGO_REF:0000002
AcacaRatATP binding enablesIEAUniRule:UR0004146451600115GO_REF:0000104UniProtGO_REF:0000104
AcacaRatbiotin binding  IDA 1601566 RGD 
AcacaRatcatalytic activity enablesIEAUniProtKB-KW:KW-05111600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatcatalytic activity enablesIEAUniProtKB-KW:KW-0021 and UniProtKB-KW:KW-05111600115GO_REF:0000043UniProtGO_REF:0000043
AcacaRatidentical protein binding enablesISOACACA (Homo sapiens)1624291UniProtKB:Q13085 and PMID:20457939RGDPMID:20457939
AcacaRatidentical protein binding enablesIEAUniProtKB:Q13085 and ensembl:ENSP000004833001600115GO_REF:0000107EnsemblGO_REF:0000107
AcacaRatkinase binding  IPINme1 (Rattus norvegicus)5132881 RGD 
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RGD Manual Annotations


  
Object Symbol
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Reference
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Source
Original Reference(s)
AcacaRatfatty acid biosynthetic pathway   IDA 2317316 RGD 
AcacaRatfatty acid biosynthetic pathway   ISOACACA (Homo sapiens)2317309 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
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Evidence
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Reference
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Original Reference(s)
AcacaRatfatty acid biosynthetic pathway   IEA 6907045 KEGGrno:00061
AcacaRatinsulin signaling pathway   IEA 6907045 KEGGrno:04910
AcacaRatpropanoate metabolic pathway  IEA 6907045 KEGGrno:00640
AcacaRatpyruvate metabolic pathway   IEA 6907045 KEGGrno:00620

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#
Reference Title
Reference Citation
1. Fermented rice bran supplementation mitigates metabolic syndrome in stroke-prone spontaneously hypertensive rats. Alauddin M, etal., BMC Complement Altern Med. 2016 Nov 8;16(1):442. doi: 10.1186/s12906-016-1427-z.
2. Changes in white adipose tissue metabolism induced by resveratrol in rats. Alberdi G, etal., Nutr Metab (Lond). 2011 May 10;8(1):29. doi: 10.1186/1743-7075-8-29.
3. [Biological-molecular trend in psychiatry] Bilikiewicz A Pol Tyg Lek 1978 Jun 26;33(26):1046-50.
4. A novel physical and functional association between nucleoside diphosphate kinase A and AMP-activated protein kinase alpha1 in liver and lung. Crawford RM, etal., Biochem J. 2005 Nov 15;392(Pt 1):201-9.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. The cytoskeleton in 'couch potato-ism': Insights from a murine model of impaired actin dynamics. Gertz K, etal., Exp Neurol. 2018 Aug;306:34-44. doi: 10.1016/j.expneurol.2018.04.004. Epub 2018 Apr 21.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals. Harwood HJ Jr, etal., J Biol Chem. 2003 Sep 26;278(39):37099-111. Epub 2003 Jul 3.
9. Fasting for 3 days during the suckling-weaning transient period in male rats induces metabolic abnormalities in the liver and is associated with impaired glucose tolerance in adulthood. Ikeda M, etal., Eur J Nutr. 2016 Apr;55(3):1059-67. doi: 10.1007/s00394-015-0919-9. Epub 2015 May 6.
10. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
11. Vestnik khirurgii imeni I. I. Grekova Kuts NL, etal., Vestn Khir Im I I Grek 1978 Nov;121(11):88-9.
12. Therapeutic Effect of Gypenosides on Nonalcoholic Steatohepatitis via Regulating Hepatic Lipogenesis and Fatty Acid Oxidation. Li H, etal., Biol Pharm Bull. 2017;40(5):650-657. doi: 10.1248/bpb.b16-00942.
13. The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment. Liang Y, etal., Metabolism. 2006 Oct;55(10):1411-9.
14. Heterogeneity at the 5' end of rat acetyl-coenzyme A carboxylase mRNA. Lipogenic conditions enhance synthesis of a unique mRNA in liver. Lopez-Casillas F and Kim KH, J Biol Chem 1989 May 5;264(13):7176-84.
15. Structure of the coding sequence and primary amino acid sequence of acetyl-coenzyme A carboxylase. Lopez-Casillas F, etal., Proc Natl Acad Sci U S A 1988 Aug;85(16):5784-8.
16. Structural features of the acetyl-CoA carboxylase gene: mechanisms for the generation of mRNAs with 5' end heterogeneity. Luo XC, etal., Proc Natl Acad Sci U S A 1989 Jun;86(11):4042-6.
17. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Menendez JA and Lupu R, Nat Rev Cancer. 2007 Oct;7(10):763-77.
18. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
19. Effect of cold acclimation on brown adipose tissue fatty acid synthesis in rats adapted to a high-protein, carbohydrate-free diet. Moura MA, etal., Metabolism. 2001 Dec;50(12):1493-8.
20. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
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PMID:1974251   PMID:2567668   PMID:2573562   PMID:2900138   PMID:7910165   PMID:8954960   PMID:16216881   PMID:16396499   PMID:17210641   PMID:17218081   PMID:17956983   PMID:18280001  
PMID:18381287   PMID:18534630   PMID:18614015   PMID:19618481   PMID:20457939   PMID:20952656   PMID:23376485   PMID:23479225   PMID:26976583   PMID:27352290   PMID:28993954   PMID:29899443  



Acaca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81069,511,627 - 69,773,888 (+)NCBIGRCr8
mRatBN7.21069,014,261 - 69,276,453 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1069,014,170 - 69,276,457 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1073,702,781 - 73,894,445 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01073,207,804 - 73,399,466 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01068,672,215 - 68,863,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01071,519,392 - 71,719,910 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1071,536,533 - 71,719,910 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01071,431,885 - 71,630,271 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,483,772 - 72,677,134 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11072,498,141 - 72,691,504 (+)NCBI
Celera1068,011,070 - 68,201,435 (+)NCBICelera
Cytogenetic Map10q26NCBI
ACACA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381737,084,992 - 37,406,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1737,084,992 - 37,406,836 (-)EnsemblGRCh38hg38GRCh38
GRCh371735,441,927 - 35,766,927 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361732,516,040 - 32,841,015 (-)NCBINCBI36Build 36hg18NCBI36
Build 341732,516,039 - 32,841,015NCBI
Celera1732,264,387 - 32,589,361 (-)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1731,594,734 - 31,704,859 (-)NCBIHuRef
HuRef1731,378,027 - 31,583,939 (-)NCBIHuRef
CHM1_11735,476,555 - 35,798,374 (-)NCBICHM1_1
T2T-CHM13v2.01738,071,975 - 38,396,996 (-)NCBIT2T-CHM13v2.0
Acaca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,020,461 - 84,292,477 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1184,020,498 - 84,292,477 (+)EnsemblGRCm39 Ensembl
GRCm381184,129,635 - 84,401,651 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,129,672 - 84,401,651 (+)EnsemblGRCm38mm10GRCm38
MGSCv371184,008,940 - 84,215,153 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361184,011,659 - 84,215,878 (+)NCBIMGSCv36mm8
Celera1193,804,708 - 94,012,980 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.29NCBI
Acaca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955451600,254 - 909,892 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955451679,033 - 909,892 (+)NCBIChiLan1.0ChiLan1.0
ACACA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21927,347,009 - 27,678,249 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11729,230,527 - 29,559,723 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01719,670,114 - 19,998,903 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11719,969,199 - 20,297,651 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1719,969,205 - 20,297,651 (+)Ensemblpanpan1.1panPan2
ACACA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,904,204 - 37,188,096 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,905,293 - 37,187,892 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha936,128,994 - 36,412,715 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0937,714,414 - 37,998,482 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl937,714,417 - 37,998,015 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1936,495,840 - 36,779,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0936,783,386 - 37,067,528 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0936,870,310 - 37,154,200 (-)NCBIUU_Cfam_GSD_1.0
Acaca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,883,567 - 36,147,281 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936490927,769 - 1,191,481 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936490927,769 - 1,191,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACACA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1238,581,457 - 38,824,712 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11238,580,916 - 38,875,067 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21240,200,228 - 40,401,426 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACACA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11630,374,166 - 30,704,635 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1630,452,343 - 30,705,004 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660771,098,931 - 1,432,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acaca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248714,105,067 - 4,412,325 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248714,103,014 - 4,364,690 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Acaca
837 total Variants

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:53
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000041140
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 79 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631565Hcuc4Hepatic copper content QTL 44.15liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)106694181373452992Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat

1 to 10 of 79 rows
D17S1255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21069,130,306 - 69,130,416 (+)MAPPERmRatBN7.2
Rnor_6.01071,575,744 - 71,575,853NCBIRnor6.0
Rnor_5.01071,485,875 - 71,485,984UniSTSRnor5.0
RGSC_v3.41072,532,258 - 72,532,367UniSTSRGSC3.4
Celera1068,057,375 - 68,057,484UniSTS
Cytogenetic Map10q26UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 30 of 35 rows
RefSeq Transcripts NM_022193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF121986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF121987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB871887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB873147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB875018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB879528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB888263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HB921072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC929296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC930556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC932427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC936937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC945672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HC978481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M26195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M26196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 35 rows

Ensembl Acc Id: ENSRNOT00000041140   ⟹   ENSRNOP00000049438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1069,066,860 - 69,276,457 (+)Ensembl
Rnor_6.0 Ensembl1071,546,977 - 71,719,910 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088138   ⟹   ENSRNOP00000073421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1069,099,659 - 69,276,457 (+)Ensembl
Rnor_6.0 Ensembl1071,536,533 - 71,719,910 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101496   ⟹   ENSRNOP00000078963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1069,066,860 - 69,276,457 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115196   ⟹   ENSRNOP00000094595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1069,066,860 - 69,276,457 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116202   ⟹   ENSRNOP00000086394
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1069,014,170 - 69,276,457 (+)Ensembl
RefSeq Acc Id: NM_022193   ⟹   NP_071529
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,580,247 - 69,773,888 (+)NCBI
mRatBN7.21069,082,796 - 69,276,453 (+)NCBI
Rnor_6.01071,519,392 - 71,719,910 (+)NCBI
Rnor_5.01071,431,885 - 71,630,271 (+)NCBI
RGSC_v3.41072,483,772 - 72,677,134 (+)RGD
Celera1068,011,070 - 68,201,435 (+)RGD
Sequence:
RefSeq Acc Id: XM_039086752   ⟹   XP_038942680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,511,627 - 69,773,888 (+)NCBI
mRatBN7.21069,014,261 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_039086753   ⟹   XP_038942681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,511,627 - 69,773,888 (+)NCBI
mRatBN7.21069,014,261 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_039086754   ⟹   XP_038942682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,564,138 - 69,773,888 (+)NCBI
mRatBN7.21069,066,698 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_039086755   ⟹   XP_038942683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,564,138 - 69,773,888 (+)NCBI
mRatBN7.21069,066,698 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_039086757   ⟹   XP_038942685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,564,138 - 69,773,888 (+)NCBI
mRatBN7.21069,066,698 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_039086758   ⟹   XP_038942686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,511,767 - 69,773,888 (+)NCBI
mRatBN7.21069,014,504 - 69,276,453 (+)NCBI
RefSeq Acc Id: XM_063269784   ⟹   XP_063125854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,578,015 - 69,773,888 (+)NCBI
RefSeq Acc Id: XM_063269785   ⟹   XP_063125855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81069,564,137 - 69,773,888 (+)NCBI
1 to 30 of 35 rows
Protein RefSeqs NP_071529 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942680 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942681 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942682 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942683 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942685 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942686 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125854 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125855 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA40652 (Get FASTA)   NCBI Sequence Viewer  
  AAA40653 (Get FASTA)   NCBI Sequence Viewer  
  AAA40654 (Get FASTA)   NCBI Sequence Viewer  
  AAA40655 (Get FASTA)   NCBI Sequence Viewer  
  AAA40656 (Get FASTA)   NCBI Sequence Viewer  
  ABL63425 (Get FASTA)   NCBI Sequence Viewer  
  ABL63426 (Get FASTA)   NCBI Sequence Viewer  
  CBF60000 (Get FASTA)   NCBI Sequence Viewer  
  CBF60635 (Get FASTA)   NCBI Sequence Viewer  
  CBF61881 (Get FASTA)   NCBI Sequence Viewer  
  CBF64062 (Get FASTA)   NCBI Sequence Viewer  
  CBF68276 (Get FASTA)   NCBI Sequence Viewer  
  CBF95526 (Get FASTA)   NCBI Sequence Viewer  
  CBU85244 (Get FASTA)   NCBI Sequence Viewer  
  CBU85853 (Get FASTA)   NCBI Sequence Viewer  
  CBU86757 (Get FASTA)   NCBI Sequence Viewer  
  CBU88938 (Get FASTA)   NCBI Sequence Viewer  
  CBU93150 (Get FASTA)   NCBI Sequence Viewer  
  CBV09046 (Get FASTA)   NCBI Sequence Viewer  
  EDM05508 (Get FASTA)   NCBI Sequence Viewer  
  EDM05509 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 35 rows
1 to 5 of 14 rows
1 to 5 of 14 rows
RefSeq Acc Id: NP_071529   ⟸   NM_022193
- UniProtKB: P97902 (UniProtKB/Swiss-Prot),   P11497 (UniProtKB/Swiss-Prot),   A1EC79 (UniProtKB/Swiss-Prot),   D3ZRA3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049438   ⟸   ENSRNOT00000041140
Ensembl Acc Id: ENSRNOP00000073421   ⟸   ENSRNOT00000088138
RefSeq Acc Id: XP_038942680   ⟸   XM_039086752
- Peptide Label: isoform X1
- UniProtKB: P97902 (UniProtKB/Swiss-Prot),   P11497 (UniProtKB/Swiss-Prot),   A1EC79 (UniProtKB/Swiss-Prot),   A0A8I6A239 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942681   ⟸   XM_039086753
- Peptide Label: isoform X2
- UniProtKB: P97902 (UniProtKB/Swiss-Prot),   P11497 (UniProtKB/Swiss-Prot),   A1EC79 (UniProtKB/Swiss-Prot)
ATP-grasp   Biotin carboxylation   Biotinyl-binding   CoA carboxyltransferase C-terminal   CoA carboxyltransferase N-terminal   Lipoyl-binding

Name Modeler Protein Id AA Range Protein Structure
AF-P11497-F1-model_v2 AlphaFold P11497 1-2345 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 40 of 73 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-23845 BioCyc
BioCyc Pathway PWY0-1264 [biotin-carboxyl carrier protein assembly] BioCyc
  PWY66-429 [fatty acid biosynthesis initiation (mitochondria)] BioCyc
BioCyc Pathway Image PWY0-1264 BioCyc
  PWY66-429 BioCyc
Ensembl Genes ENSRNOG00000034013 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000115196 ENTREZGENE
  ENSRNOT00000116202 ENTREZGENE
Gene3D-CATH 2-enoyl-CoA Hydratase, Chain A, domain 1 UniProtKB/Swiss-Prot
  2.40.50.100 UniProtKB/Swiss-Prot
  3.30.1490.20 UniProtKB/Swiss-Prot
  3.40.50.20 UniProtKB/Swiss-Prot
  ATP-grasp fold, B domain UniProtKB/Swiss-Prot
  Biotin dependent carboxylase carboxyltransferase UniProtKB/Swiss-Prot
  PreATP-grasp domain UniProtKB/Swiss-Prot
InterPro ACCA UniProtKB/Swiss-Prot
  ACCA_BT UniProtKB/Swiss-Prot
  AcCoA_carboxyl UniProtKB/Swiss-Prot
  AcCoA_COase_cen UniProtKB/Swiss-Prot
  ATP-grasp UniProtKB/Swiss-Prot
  ATP_grasp_subdomain_1 UniProtKB/Swiss-Prot
  BC-like_N UniProtKB/Swiss-Prot
  Biotin_BS UniProtKB/Swiss-Prot
  Biotin_carboxylation_dom UniProtKB/Swiss-Prot
  Biotin_COase_C UniProtKB/Swiss-Prot
  Biotin_lipoyl UniProtKB/Swiss-Prot
  CbamoylP_synth_lsu-like_ATP-bd UniProtKB/Swiss-Prot
  ClpP/crotonase-like_dom_sf UniProtKB/Swiss-Prot
  COA_CT_C UniProtKB/Swiss-Prot
  COA_CT_N UniProtKB/Swiss-Prot
  PreATP-grasp_dom_sf UniProtKB/Swiss-Prot
  Rudment_hybrid_motif UniProtKB/Swiss-Prot
  Single_hybrid_motif UniProtKB/Swiss-Prot
KEGG Report rno:60581 UniProtKB/Swiss-Prot
NCBI Gene 60581 ENTREZGENE
PANTHER ACETYL-COA CARBOXYLASE 1 UniProtKB/Swiss-Prot
  ACETYL-COA CARBOXYLASE, ISOFORM A UniProtKB/Swiss-Prot
Pfam ACC_central UniProtKB/Swiss-Prot
  ACCA_BT UniProtKB/Swiss-Prot
  Biotin_carb_C UniProtKB/Swiss-Prot
1 to 40 of 73 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Acaca  acetyl-CoA carboxylase alpha  Acaca  acetyl-coenzyme A carboxylase alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Acaca  acetyl-coenzyme A carboxylase alpha  Acac  acetyl-coenzyme A carboxylase  Symbol and Name updated 1299863 APPROVED
2002-08-07 Acac  acetyl-coenzyme A carboxylase      Symbol and Name status set to provisional 70820 PROVISIONAL