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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621248
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acaca
Name: acetyl-CoA carboxylase alpha
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acacaaffects expressionISOAcaca (Mus musculus)6480464CTDCarbon Tetrachloride affects the expression of ACACA mRNAPMID:31919559
Acacadecreases phosphorylationISOAcaca (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased phosphorylation of ACACA proteinPMID:27916511
Acacamultiple interactionsISOAcaca (Mus musculus)6480464CTDDrugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in decreased phosphorylation of ACACA protein]; Plant Extracts inhibits the reaction [Carbon Tetrachloride results in decreased phosphorylation of ACACA protein]PMID:27916511
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