GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Acaca | decreases phosphorylation | EXP | | 6480464 | CTD | Ethanol results in decreased phosphorylation of ACACA protein | PMID:26115886 PMID:29940154 | Acaca | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of ACACA mRNA | PMID:19371623 PMID:34470993 | Acaca | multiple interactions | EXP | | 6480464 | CTD | 3-(3,4-dimethoxyphenyl)propenoic acid inhibits the reaction [Ethanol results in decreased phosphorylation of ACACA protein]; [Dietary Fats co-treated with Ethanol] results in increased expression of ACACA mRNA; honokiol inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; Scopoletin inhibits the reaction [Ethanol results in decreased phosphorylation of ACACA protein]; Silymarin inhibits the reaction [Ethanol results in decreased phosphorylation of ACACA protein] | PMID:19371623 PMID:24275070 PMID:26115886 PMID:29940154 | Acaca | affects splicing | ISO | Acaca (Mus musculus) | 6480464 | CTD | Ethanol affects the splicing of ACACA mRNA | PMID:30319688 | Acaca | decreases expression | ISO | Acaca (Mus musculus) | 6480464 | CTD | Ethanol results in decreased expression of ACACA mRNA; Ethanol results in decreased expression of ACACA protein | PMID:28882574 PMID:34995708 | Acaca | decreases phosphorylation | ISO | ACACA (Homo sapiens) | 6480464 | CTD | Ethanol results in decreased phosphorylation of ACACA protein | PMID:29940154 | Acaca | increases expression | ISO | Acaca (Mus musculus) | 6480464 | CTD | Ethanol results in increased expression of ACACA mRNA; Ethanol results in increased expression of ACACA protein | PMID:18620774 PMID:18755807 PMID:19167417 PMID:20637825 PMID:24144995 PMID:24146112 PMID:27984176 PMID:28935932 PMID:30319688 | Acaca | multiple interactions | ISO | Acaca (Mus musculus) | 6480464 | CTD | 5-aminoisoquinolinone inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; [ADORA1 gene mutant form results in increased susceptibility to Ethanol] which results in increased expression of ACACA mRNA; [Zinc deficiency co-treated with Ethanol] results in decreased expression of ACACA mRNA; Cannabidiol inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; Cannabidiol inhibits the reaction [Ethanol results in increased expression of ACACA protein]; Chlormethiazole inhibits the reaction [Ethanol results in decreased phosphorylation of and results in decreased expression of ACACA protein]; Ethanol inhibits the reaction [Fish Oils results in decreased expression of ACACA mRNA]; Ethanol results in decreased phosphorylation of and results in decreased expression of ACACA protein; gadolinium chloride promotes the reaction [Ethanol results in decreased expression of ACACA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; PARP1 protein affects the reaction [Ethanol results in increased expression of ACACA mRNA]; pirinixic acid inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; Resveratrol inhibits the reaction [Ethanol results in increased expression of ACACA mRNA]; withaferin A promotes the reaction [Ethanol results in decreased expression of ACACA mRNA] | PMID:18620774 PMID:18755807 PMID:23692951 PMID:24155903 PMID:24892905 PMID:27984176 PMID:28882574 PMID:28935932 PMID:34995708 | Acaca | multiple interactions | ISO | ACACA (Homo sapiens) | 6480464 | CTD | 3-(3,4-dimethoxyphenyl)propenoic acid inhibits the reaction [Ethanol results in decreased phosphorylation of ACACA protein] | PMID:29940154 | | ||||||||||||||||||||||
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