Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621248
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acaca
Name: acetyl-CoA carboxylase alpha
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acacaincreases expressionEXP 6480464CTDGlucose results in increased expression of ACACA mRNAPMID:24349266
Acacadecreases expressionISOACACA (Homo sapiens)6480464CTDGlucose results in decreased expression of ACACA protein modified formPMID:33838154
Acacadecreases phosphorylationISOACACA (Homo sapiens)6480464CTDGlucose results in decreased phosphorylation of ACACA proteinPMID:18482975 PMID:19071085
Acacaincreases expressionISOAcaca (Mus musculus)6480464CTDGlucose results in increased expression of ACACA mRNAPMID:15066988
Acacamultiple interactionsISOACACA (Homo sapiens)6480464CTD[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA; [Pyruvic Acid co-treated with Glucose] results in increased phosphorylation of ACACA protein; PRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]]; SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA]PMID:18482975 PMID:19071085 PMID:19724016
Go Back to source page   Continue to Ontology report