Slc2a4 Rat Gene (solute carrier family 2 (facilitated glucose transporter), member 4)

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Keyword

Gene:
Slc2a4 ( Rattus norvegicus )
solute carrier family 2 (facilitated glucose transporter), member 4
Description: transports glucose; may play a role in insulin response
Synonyms: Glucose transporter 4, insuline-responsive; Glut4; solute carrier family 2 , member 4; Glucose transporter 4 insuline-responsive; MGC93607; solute carrier family 2 (facilitated glucose transporter) member 4;  (details...)
ArrayIDs: 6320095; 6056309; D28561_s_at; 6679107; 5741657; 1367989_at; 6165542; 6149885; 6419862; 6353704; 1388958_a_at; rc_AA799760_s_at; 6713144; 6200806; A_44_P477406; A_44_P311360; 5985051; A_42_P757990; 1388914_at; 6557845; GE19942; 6283343; 5661633; 6291048; 6326852; 5794164; 6440866; 6011713; 6174243;  (details...)
Gene Type: protein-coding

Additional Data

Markers: D10Uwm1

Homologs
Homo sapiens: SLC2A4     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Slc2a4     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Slc2a4 genome assembly 3.1 10 56800327 - 56805832
Rat Celera Assembly 10 53819953 - 53825446
RGSC genome assembly v3.4 10 56786705 - 56792209
Cytogenetic 10 q24
Mus musculus Slc2a4 Mouse genome assembly build 36.1 11 69755788 - 69761692
Cytogenetic 11 11 C-E1
Homo sapiens SLC2A4 human genome assembly 17 7125834 - 7131125
Human genome assembly build 36.2 17 7125778 - 7132091
Cytogenetic 17 p13

View comparative maps:      NCBI MapViewer

Genome
View:

Browsers:

Other Map Data:
Associated SSLP Map Locations
STS D10Uwm1 genome assembly 3.1 10 56806201 - 56806359
Rat cytogenetic map 10
RGSC genome assembly v3.4 10 56792578 - 56792736

Annotation
Molecular Function

Gene Ontology

D-glucose transmembrane transporter activity,  protein binding,  transporter activity ... (details...)
Biological Process

Gene Ontology

transmembrane transport,  glucose homeostasis,  brown fat cell differentiation ... (details...)
Cellular Component

Gene Ontology

integral to membrane of membrane fraction,  trans-Golgi network transport vesicle,  soluble fraction ... (details...)
Disease

Ontology

Diabetes Mellitus, Experimental,  Heart Failure, Congestive,  Hypertension, Pulmonary ... (details...)
Pathway

Ontology

facilitative sugar transporter mediated glucose transport pathway,  insulin responsive facilitative sugar transporter mediated glucose transport pathway (details...)
Regulation

Note Reference

Glut4 intracellular trafficking and localization is regulated by insulin 727471

External Links
Databases
DATABASE ID SOURCE
PROSITE: SUGAR_TRANSPORT_1 IPI
PROSITE: SUGAR_TRANSPORT_2 IPI
PROSITE: MFS IPI
UNIPARC: UPI00000371BC IPI
KEGG Report: rno:25139 ENTREZGENE
HomoloGene Group ID: 74381 ENTREZGENE
Germonline: 2711
Pfam: Sugar_tr IPI
KEGG Pathway: 04930 ENTREZGENE
KEGG Pathway: 04920 ENTREZGENE
KEGG Pathway: 04910 ENTREZGENE
InterPro: Sub_transporter. IPI
InterPro: MFS_general_subst_transpt. IPI
InterPro: Glc_transpt_4. IPI
InterPro: Sugar/inositol_transpt. IPI
InterPro: Sugar_transporter_CS. IPI
InterPro: Major_facilitator_SF. IPI
Ensembl Protein: ENSRNOP00000023256 IPI
IPI: IPI00194348 IPI
Entrez Gene: Slc2a4 ENTREZGENE
IMAGE_CLONE: IMAGE:7192278 IMAGE-MGC_LOAD
MGC_CLONE: MGC:93607 IMAGE-MGC_LOAD
Ensembl Genes: ENSRNOG00000017226 IPI
TIGR: TC205760
UniProt: GTR4_RAT IPI
Superfamily-SCOP: MFS_gen_substrate_transporter IPI
RatMap: 39651 ENTREZGENE
TIGRFAMs: SP IPI
PRINTS: SUGRTRNSPORT. IPI
PRINTS: GLUCTRSPORT4. IPI
Sequences
Nucleotide: BC085757 Get FASTA Search GEO Profiles
Nucleotide: M25482 Get FASTA Search GEO Profiles
Nucleotide: J04524 Get FASTA Search GEO Profiles
Nucleotide: D28561 Get FASTA Search GEO Profiles
Nucleotide: X14771 Get FASTA Search GEO Profiles
Nucleotide: L36125 Get FASTA Search GEO Profiles
Nucleotide: CH473948 Get FASTA Search GEO Profiles
Nucleotide: NM_012751 Get FASTA Search GEO Profiles
(View all 8 Nucleotide Accessions)
Protein: NP_036883 Get FASTA
Protein: EDM04935 Get FASTA
Protein: EDM04936 Get FASTA
Protein: P19357 Get FASTA
Protein: CAA32879 Get FASTA
Protein: AAA41451 Get FASTA
Protein: AAA41453 Get FASTA
Protein: BAA05911 Get FASTA
Protein: AAH85757 Get FASTA
Protein: AAA65751 Get FASTA
Protein: EDM04938 Get FASTA
Protein: EDM04937 Get FASTA
(View all 12 Protein Accessions)
Clusters
UniGene: 1314

References
Curated References
40 references in RGD related to Slc2a4

Other References
113 other references at PubMed related to Slc2a4

Database Information
RGD ID 2711
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

10-SEP-04: Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 solute carrier family 2 , member 4 APPROVED Name updated 1299863

06-NOV-02: Slc2a4 solute carrier family 2 , member 4 Glut4 Glucose transporter 4, insuline-responsive APPROVED Symbol and Name updated 625702

10-JUN-02: Glut4 Glucose transporter 4, insuline-responsive APPROVED Symbol and Name status set to approved 70586