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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2711
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a4
Name: solute carrier family 2 member 4
Acc ID: CHEBI:44445
Term: nimesulide
Definition: An aromatic ether having phenyl and 2-methylsulfonamido-5-nitrophenyl as the two aryl groups.
Chemical ID: MESH:C012655
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a4increases expressionISOSlc2a4 (Mus musculus)6480464CTDnimesulide results in increased expression of SLC2A4 mRNA; nimesulide results in increased expression of SLC2A4 proteinPMID:16447059
Slc2a4multiple interactionsISOSlc2a4 (Mus musculus)6480464CTD[nimesulide results in increased expression of SLC2A4 protein] which results in increased uptake of HexosesPMID:16447059
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