GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc2a4 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of SLC2A4 mRNA | PMID:1727734 | Slc2a4 | increases expression | EXP | | 6480464 | CTD | Glucose results in increased expression of SLC2A4 mRNA | PMID:15111496 | Slc2a4 | multiple interactions | EXP | | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Chloroquine affects the localization of SLC2A4 protein] which results in increased uptake of Glucose]; [[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose; ESR1 protein promotes the reaction [[Resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose]; Fulvestrant inhibits the reaction [[Resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose] | PMID:18426865 PMID:27160165 | Slc2a4 | decreases expression | ISO | SLC2A4 (Homo sapiens) | 6480464 | CTD | Glucose results in decreased expression of SLC2A4 protein | PMID:33957017 | Slc2a4 | increases uptake | ISO | Slc2a4 (Mus musculus) | 6480464 | CTD | SLC2A4 protein results in increased uptake of Glucose | PMID:19373748 PMID:19477051 | Slc2a4 | multiple interactions | ISO | SLC2A4 (Homo sapiens) | 6480464 | CTD | ACACB protein affects the reaction [Glucose results in decreased expression of SLC2A4 protein] | PMID:33957017 | Slc2a4 | multiple interactions | ISO | Slc2a4 (Mus musculus) | 6480464 | CTD | [3,3',4,5'-tetrahydroxystilbene results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose; [Glucose co-treated with picolinic acid] affects the localization of SLC2A4 protein; Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine]; mangiferin promotes the reaction [SLC2A4 protein results in increased uptake of Glucose]; MYH2 protein affects the reaction [SLC2A4 protein results in increased uptake of Glucose]; Plant Extracts promotes the reaction [SLC2A4 protein results in increased uptake of Glucose] | PMID:16870493 PMID:18773891 PMID:19373748 PMID:19477051 PMID:22579688 | |
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