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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2711
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a4
Name: solute carrier family 2 member 4
Acc ID: CHEBI:17243
Term: mono(2-ethylhexyl) phthalate
Definition: The mono(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:C016599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a4multiple interactionsEXP 6480464CTD[INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in decreased expression of SLC2A4 protein; [INS1 protein co-treated with mono-(2-ethylhexyl)phthalate] results in increased phosphorylation of SLC2A4 protein; mono-(2-ethylhexyl)phthalate inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]PMID:28526321
Slc2a4increases expressionISOSlc2a4 (Mus musculus)6480464CTDmono-(2-ethylhexyl)phthalate results in increased expression of SLC2A4 mRNAPMID:25543134
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