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Pathways
Genes search result for Rattus norvegicus
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74 records found for search term Tox
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1310455Toxthymocyte selection-associated high mobility group boxENCODES a protein that exhibits chromatin DNA binding (ortholog); INVOLVED IN CD4-positive, alpha-beta T cell lineage commitment (ortholog); CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment (ortholog); CD8-positive, alpha-beta T cell lineage commitment (ortholog); FOUND I52467248724968754Rat136symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
735184Tox2TOX high mobility group box family member 2ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding; transcription coactivator activity (ortholog); INVOLVED IN female gonad development; positive regulation of transcription by RNA polymerase II; response to gonadotropin; FOUND IN nucleoplasm (ortholo3172272718172400235Rat91symbol , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1311529Tox3TOX high mobility group box family member 3ENCODES a protein that exhibits chromatin binding (ortholog); phosphoprotein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN calcium-mediated signaling; positive regulation of DNA-templated transcription; negative regulation of neuron apoptotic process (ortholog); ASSOC193282095732929776Rat137symbol , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
708449Tox4TOX high mobility group box family member 4ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of transcription elongation by RNA polymerase II (ortholog); RNA polymerase II promoter clearance (ortholog); FOUND IN chromatin (ortholog);152746273527476320Rat87symbol , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1585613Tox3l1TOX high mobility group box family member 3 like 12155710403155742735Ratsymbol , PhenoGen , namegene, ncrna, VALIDATED [RefSeq]
41057908Tox4-ps1TOX high mobility group box family member 4, pseudogene 17102517681102592288Ratsymbol , old_gene_name , PhenoGen , namegene, pseudo, MODEL [RefSeq]
2771Gucy2cguanylate cyclase 2CENCODES a protein that exhibits guanylate cyclase activity; toxic substance binding; INVOLVED IN regulation of cell population proliferation (ortholog); response to toxic substance (ortholog); PARTICIPATES IN purine metaboli4171299715171380296Rat117old_gene_name , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1307144Antxr1ANTXR cell adhesion molecule 1ENCODES a protein that exhibits actin filament binding (ortholog); collagen binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); blood vessel development (ortholog); negative regulation of extracellular matrix assembly (ortholog); ASSOCI4121148102121335549Rat196old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1561294Antxr2ANTXR cell adhesion molecule 2ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); INVOLVED IN collagen fibril organization (ortholog); single fertilization (ortholog); uterus development (ortholog); ASSOCIATED WITH anthrax disease; ankylosing spondylitis (ortholog); congenital my141184577411986166Rat162old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2526Hbegfheparin-binding EGF-like growth factorENCODES a protein that exhibits epidermal growth factor receptor binding; growth factor activity; heparin binding (ortholog); INVOLVED IN epidermal growth factor receptor signaling pathway; negative regulation of glycoprotein biosynthetic process; positive regulation of cell growth; PARTICIPATES IN 182838033728390220Rat413old_gene_name , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1563190Antxrl1ANTXR like 1ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); FOUND IN membrane (inferred); INTERACTS WITH atrazine; bisphenol A; 1,2-dimethylhydrazine (ortholog)1693690469393569Rat19old_gene_namegene, protein-coding, VALIDATED [RefSeq]
6500283Antxrl2ANTXR like 2ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); FOUND IN membrane (inferred)1693062939338559Rat7old_gene_namegene, protein-coding, MODEL [RefSeq]
1596785Antxrl3ANTXR like 3ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); FOUND IN membrane (inferred)1693379859364423Rat7old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1310963Nlrp1aNLR family, pyrin domain containing 1AENCODES a protein that exhibits scaffold protein binding; ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN negative regulation of cellular defense response; positive regulation of pyroptotic inflammatory response; antiviral innate immune response (ortholog); PARTICIPATES IN in105627713456332229Rat176old_gene_namegene, protein-coding, VALIDATED [RefSeq]
708448Phaxphosphorylated adaptor for RNA exportENCODES a protein that exhibits toxic substance binding; mRNA cap binding complex binding (ortholog); INVOLVED IN RNA stabilization (ortholog); snRNA export from nucleus (ortholog); PARTICIPATES IN RNA transport pathway; ASSOCIATED WITH Hirschsprung's disease (o185225123152267916Rat84old_gene_name , descriptiongene, protein-coding, VALIDATED [RefSeq]
1304634Dph2diphthamide biosynthesis 2ENCODES a protein that exhibits 2-(3-amino-3-carboxypropyl)histidine synthase activity (ortholog); 4 iron, 4 sulfur cluster binding (ortholog); INVOLVED IN protein histidyl modification to diphthamide (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); diphthamide deficiency syndrome 5136713868136716828Rat90old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1311123Slc47a1solute carrier family 47 member 1ENCODES a protein that exhibits amide transmembrane transporter activity; polyspecific organic cation:proton antiporter activity; xenobiotic transmembrane transporter activity; INVOLVED IN monoatomic cation transmembrane transport; monoatomic cation transport; organic cation transport; PARTICIPATES 104653358046590128Rat310old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1562382Slc47a2solute carrier family 47 member 2ENCODES a protein that exhibits antiporter activity (ortholog); polyspecific organic cation:proton antiporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN organic cation transport (ortholog); PARTICIPATES IN metformin pharmacokinetics pathway; FOUND IN plasma membr104649026246532954Rat133old_gene_namegene, protein-coding, INFERRED [RefSeq]
619755Rac1Rac family small GTPase 1ENCODES a protein that exhibits ATPase binding; GTP binding; GTPase activity; INVOLVED IN actin cytoskeleton organization; actin filament organization; bone resorption; PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; Arf family mediated signaling pathway; azathioprine pharmacodynamics path121615041116170864Rat639old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1307568Rac2Rac family small GTPase 2ENCODES a protein that exhibits GTP binding (ortholog); GTPase activity (ortholog); protein kinase regulator activity (ortholog); INVOLVED IN actin cytoskeleton organization; bone resorption; actin filament organization (ortholog); PARTICIPATES IN B cell receptor signaling pathway; ceramide signalin7111981825112009201Rat274old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1590052Rac3Rac family small GTPase 3ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); GTPase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell projection assembly (ortholog); cerebral cortex GABAergic interneuron development (ortholog); ASSOCIATED WITH acute myeloid leukemia 10106501133106503569Rat158old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3521Art2bADP-ribosyltransferase 2bENCODES a protein that exhibits hydrolase activity, acting on glycosyl bonds (ortholog); NAD+-protein-arginine ADP-ribosyltransferase activity (ortholog); INVOLVED IN NAD+ catabolic process (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl 1165368623165386280Rat32old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
628834Art5ADP-ribosyltransferase 5ENCODES a protein that exhibits NAD+ nucleosidase activity (ortholog); NAD+-protein-arginine ADP-ribosyltransferase activity (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide1165885344165895306Rat60old_gene_namegene, protein-coding, VALIDATED [RefSeq]
2053Parp1poly (ADP-ribose) polymerase 1ENCODES a protein that exhibits enzyme binding; histone deacetylase binding; NAD binding; INVOLVED IN carbohydrate biosynthetic process; cellular response to amyloid-beta; cellular response to nerve growth factor stimulus; PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; base ex139483948494871295Rat2342old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1306243Parp16poly (ADP-ribose) polymerase family, member 16ENCODES a protein that exhibits kinase binding (ortholog); NAD+ poly-ADP-ribosyltransferase activity (ortholog); NAD+-protein mono-ADP-ribosyltransferase activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); endoplasmic reticulum unfolded protein response (orth87462639974644610Rat123old_gene_namegene, protein-coding, VALIDATED [RefSeq]
628694Zc3hav1zinc finger CCCH-type containing, antiviral 1ENCODES a protein that exhibits identical protein binding; RNA binding; NAD+ binding (ortholog); INVOLVED IN cellular response to virus; negative regulation of viral genome replication; positive regulation of mRNA catabolic process; PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylatio46797905568029353Rat162old_gene_namegene, protein-coding, VALIDATED [RefSeq]
621583A4galtalpha 1,4-galactosyltransferaseENCODES a protein that exhibits galactosyltransferase activity; lactosylceramide 4-alpha-galactosyltransferase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN globoside biosynthetic process (ortholog); plasma membrane organization (ortholog)7116248571116272917Rat76descriptiongene, protein-coding, VALIDATED [RefSeq]
620724Abtb2ankyrin repeat and BTB domain containing 2ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitro3110409672110563488Rat118descriptiongene, protein-coding, VALIDATED [RefSeq]
1596307Aqp10aquaporin 10ENCODES a protein that exhibits glycerol channel activity (ortholog); water channel activity (ortholog); INVOLVED IN glycerol transmembrane transport (ortholog); protein homotetramerization (ortholog); response to toxic substance (ortholog); PARTICIPATES IN wate2177699717177704620Rat62descriptiongene, protein-coding, MODEL [RefSeq]
2318374Arhgap33Rho GTPase activating protein 33ENCODES a protein that exhibits GTPase activator activity (ortholog); protein kinase binding (ortholog); INVOLVED IN regulation of dendritic spine morphogenesis; response to toxic substance; regulation of postsynapse assembly (ortholog); ASSOCIATED WITH autism s19490356694917074Rat80descriptiongene, protein-coding, VALIDATED [RefSeq]
621325As3mtarsenite methyltransferaseENCODES a protein that exhibits arsenite methyltransferase activity; INVOLVED IN arsonoacetate metabolic process; response to arsenic-containing substance; toxin metabolic process; PARTICIPATES IN homocysteine metabolic pathway; methionine cycle/metabolic pathwa1255536879255569245Rat246descriptiongene, protein-coding, VALIDATED [RefSeq]
2163Ass1argininosuccinate synthase 1ENCODES a protein that exhibits argininosuccinate synthase activity; toxic substance binding; amino acid binding (ortholog); INVOLVED IN acute-phase response; argininosuccinate metabolic process; cellular response to amine stimulus; PARTICIPATES IN urea cycle pa33514476535194632Rat431descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1304668Blmhbleomycin hydrolaseENCODES a protein that exhibits aminopeptidase activity (ortholog); identical protein binding (ortholog); peptidase activity (ortholog); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Alzheimer's d106227017062313349Rat107descriptiongene, protein-coding, VALIDATED [RefSeq]
69069Ccl5C-C motif chemokine ligand 5ENCODES a protein that exhibits chemokine activity; heparin binding; CCR1 chemokine receptor binding (ortholog); INVOLVED IN cellular response to alkyl hydroperoxide; cellular response to amino acid stimulus; cellular response to cytokine stimulus; PARTICIPATES IN syndecan signaling pathway; Chagas 106882033068824906Rat907descriptiongene, protein-coding, VALIDATED [RefSeq]
1561104Cd209dCD209d moleculeENCODES a protein that exhibits cell adhesion receptor activity (ortholog); D-mannose binding (ortholog); identical protein binding (ortholog); INVOLVED IN B cell adhesion (ortholog); defense response to bacterium (ortholog); dendritic cell migration (ortholog); ASSOCIATED WITH acquired immunodefici1266890026695452Rat87descriptiongene, protein-coding, PROVISIONAL [RefSeq]
619745Cdh13cadherin 13ENCODES a protein that exhibits adiponectin binding (ortholog); cadherin binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to toxic substance; cellular response to xenobiotic stimulus; calcium-dependent cell-cell adhesion (o196325825164296122Rat281descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620860Crispld2cysteine-rich secretory protein LCCL domain containing 2ENCODES a protein that exhibits glycosaminoglycan binding (ortholog); heparin binding (ortholog); INVOLVED IN lung development; extracellular matrix organization (ortholog); face morphogenesis (ortholog); ASSOCIATED WITH liver disease (ortholog); lung disease (ortholog); tox196496176465020099Rat172descriptiongene, protein-coding, VALIDATED [RefSeq]
2476Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 4ENCODES a protein that exhibits monooxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (ortholog); INVOLVED IN trichloroethylene metabolic proc19154376891557553Rat206descriptiongene, protein-coding, VALIDATED [RefSeq]
621227Daxxdeath-domain associated proteinENCODES a protein that exhibits JUN kinase binding; kinesin binding; nuclear androgen receptor binding; INVOLVED IN cellular response to hydrogen peroxide; cellular response to tumor necrosis factor; cellular response to type II interferon; PARTICIPATES IN aldosterone signaling pathway; histone modi2049719734978062Rat317descriptiongene, protein-coding, VALIDATED [RefSeq]
1308072Dhx15DEAH-box helicase 15ENCODES a protein that exhibits double-stranded RNA binding (ortholog); RNA binding (ortholog); RNA helicase activity (ortholog); INVOLVED IN response to alkaloid; response to toxic substance; antiviral innate immune response (ortholog); PARTICIPATES IN ribosome146299988663037829Rat131descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1306518Fbxw4F-box and WD repeat domain containing 4INVOLVED IN cartilage development (ortholog); embryonic digit morphogenesis (ortholog); limb development (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); split hand-foot malformation (ortholog); split hand-foot malformation 3 (ortholog); INTERACTS WITH bisphenol A; flutamide; T-2 tox1254375921254465173Rat56descriptiongene, protein-coding, PROVISIONAL [RefSeq]
61845Gfergrowth factor, augmenter of liver regenerationENCODES a protein that exhibits flavin-dependent sulfhydryl oxidase activity; flavin adenine dinucleotide binding (ortholog); protein-disulfide reductase activity (ortholog); INVOLVED IN cellular response to actinomycin D; cellular response to lipopolysaccharide; cellular response to tox101422302314225736Rat135descriptiongene, protein-coding, VALIDATED [RefSeq]
1309970Gsta4glutathione S-transferase alpha 4ENCODES a protein that exhibits toxic substance binding; glutathione transferase activity (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to lithium ion; response to herbicide; response to nicotine; PARTICIPATES IN glutathione con88794724787964490Rat422descriptiongene, protein-coding, PROVISIONAL [RefSeq]
2758Gstp1glutathione S-transferase pi 1ENCODES a protein that exhibits protein kinase binding; toxic substance binding; dinitrosyl-iron complex binding (ortholog); INVOLVED IN animal organ regeneration; cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; 1210767237210770242Rat1183descriptiongene, protein-coding, VALIDATED [RefSeq]
619989Ido1indoleamine 2,3-dioxygenase 1ENCODES a protein that exhibits amino acid binding; indoleamine 2,3-dioxygenase activity; oxygen binding; INVOLVED IN L-tryptophan catabolic process to L-kynurenine; inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); PARTICIPATES IN tryptophan metabolic pathway; kynure167413325974145328Rat254descriptiongene, protein-coding, VALIDATED [RefSeq]
12879433Ift140em1Kyointraflagellar transport 140; CRISPR/Cas9 induced mutant 1, KyoThis allele was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 1 (em1) has 2-bp insertion (c.23_24insGG) in the exon 1 of Ift140 (intraflagellar transporRatdescriptiongene, allele
12879435Ift140em2Kyointraflagellar transport 140; CRISPR/Cas9 induced mutant 2, KyoThis allele was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 2 (em2) has 2-bp deletion (c.23_24del) in the exon 1 of Ift140 (intraflagellar transport 1Ratdescriptiongene, allele
1306896Igtpinterferon gamma induced GTPaseENCODES a protein that exhibits GTP binding (inferred); hydrolase activity (inferred); nucleotide binding (inferred); PARTICIPATES IN toxoplasmosis pathway; FOUND IN membrane (inferred); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benz104287504742882866Rat59descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1307335Il20rainterleukin 20 receptor subunit alphaENCODES a protein that exhibits interleukin-20 binding (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); regulation of bone resorption (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-S11624368316313229Rat63descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1566151Il20rbinterleukin 20 receptor subunit betaENCODES a protein that exhibits interleukin-20 binding (ortholog); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); immune response-inhibiting signal transduction (ortholog); inflammatory response to antigenic stimulus (ortholog); PARTICIPATES IN cytokine mediated signaling pat8109858108109896066Rat106descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620873Il23ainterleukin 23 subunit alphaENCODES a protein that exhibits cytokine activity (ortholog); interleukin-23 receptor binding (ortholog); INVOLVED IN cell surface receptor signaling pathway via JAK-STAT (ortholog); cell surface receptor signaling pathway via STAT (ortholog); defense response to Gram-negative bacterium (ortholog); 713063201308434Rat342descriptiongene, protein-coding, PROVISIONAL [RefSeq]
2896Il2rbinterleukin 2 receptor subunit betaENCODES a protein that exhibits interleukin-2 binding; interleukin-2 receptor activity; coreceptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway; interleukin-15-mediated signaling pathway (ortholog); interleukin-2-mediated signaling pathway (ortholog); PARTICIPATES IN interleu7111913828111928537Rat184descriptiongene, protein-coding, VALIDATED [RefSeq]
628829Kcnc2potassium voltage-gated channel subfamily C member 2ENCODES a protein that exhibits delayed rectifier potassium channel activity; transmembrane transporter binding; voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential; INVOLVED IN cellular response to ammonium ion; cellular response to nitric oxide; c74958627449770212Rat186descriptiongene, protein-coding, VALIDATED [RefSeq]
1560601Kdm5clysine demethylase 5CENCODES a protein that exhibits histone H3K4 demethylase activity (ortholog); identical protein binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN response to toxic substance; gene expression (orthologX2482156824866423Rat123descriptiongene, protein-coding, VALIDATED [RefSeq]
1310787Lao1L-amino acid oxidase 1ENCODES a protein that exhibits L-amino-acid oxidase activity (inferred); oxidoreductase activity (inferred); toxin activity (inferred); INVOLVED IN defense response to bacterium (inferred); modulation of process of another organism (inferred); PARTICIPATES IN a5137859033137868926Rat19descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1309329Lrp5LDL receptor related protein 5ENCODES a protein that exhibits coreceptor activity (ortholog); toxin transmembrane transporter activity (ortholog); Wnt receptor activity (ortholog); INVOLVED IN response to peptide hormone; retina vasculature morphogenesis in camera-type eye; adipose tissue de1210243499210346886Rat322descriptiongene, protein-coding, VALIDATED [RefSeq]
1302993Ly96lymphocyte antigen 96ENCODES a protein that exhibits lipopolysaccharide immune receptor activity (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); detection of lipopolysaccharide (ortholog); lipopolysaccharide-mediated signaling pathway (ortholog); PARTICIPATES IN Toll-like receptor signaling p573655367397864Rat198descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1359517MapdaN6-Methyl-AMP deaminaseENCODES a protein that exhibits N6-methyl-AMP deaminase activity (ortholog); INVOLVED IN toxic metabolite repair (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate3128555604128583809Rat68descriptiongene, protein-coding, VALIDATED [RefSeq]
3046Mapk3mitogen activated protein kinase 3ENCODES a protein that exhibits ATP binding; MAP kinase activity; scaffold protein binding; INVOLVED IN arachidonate metabolic process; cellular response to toxic substance; decidualization; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signalin1190797189190803411Rat3590descriptiongene, protein-coding, VALIDATED [RefSeq]
628649Mc2rmelanocortin 2 receptorENCODES a protein that exhibits corticotropin receptor activity (ortholog); INVOLVED IN placenta development; adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); positive regulation of glucocorticoid biosynthetic process (ortholog); PARTICIPATES IN G protein mediate186427987864291775Rat99descriptiongene, protein-coding, VALIDATED [RefSeq]
620937Mlh1mutL homolog 1ENCODES a protein that exhibits chromatin binding (ortholog); enzyme activator activity (ortholog); enzyme binding (ortholog); INVOLVED IN response to hypoxia; response to toxic substance; response to xenobiotic stimulus; PARTICIPATES IN altered mismatch repair 8120074871120112109Rat500descriptiongene, protein-coding, VALIDATED [RefSeq]
3160Nefmneurofilament medium chainENCODES a protein that exhibits protein-containing complex binding; signaling receptor binding; toxic substance binding; INVOLVED IN axon regeneration; cellular response to estradiol stimulus; cellular response to oxidative stress; PARTICIPATES IN amyotrophic la154653585746541161Rat243descriptiongene, protein-coding, VALIDATED [RefSeq]
3240P2rx1purinergic receptor P2X 1ENCODES a protein that exhibits ATP binding; extracellularly ATP-gated monoatomic cation channel activity; identical protein binding; INVOLVED IN monoatomic cation transmembrane transport; monoatomic ion transmembrane transport; neuronal action potential; PARTICIPATES IN calcium/calcium-mediated sig105811710758132167Rat169descriptiongene, protein-coding, VALIDATED [RefSeq]
628670Ppifpeptidylprolyl isomerase FENCODES a protein that exhibits cyclosporin A binding; peptide binding; peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN regulation of apoptotic process; regulation of mitochondrial membrane permeability; apoptotic mitochondrial changes (ortholog); PARTICIPATES IN tox1612640011270722Rat255descriptiongene, protein-coding, PROVISIONAL [RefSeq]
632280Ppp1r9aprotein phosphatase 1, regulatory subunit 9AENCODES a protein that exhibits actin filament binding; GTPase binding; identical protein binding; INVOLVED IN cellular response to toxic substance; excitatory postsynaptic potential; negative regulation of long-term synaptic potentiation; ASSOCIATED WITH hepato43393694934258927Rat206descriptiongene, protein-coding, VALIDATED [RefSeq]
1563360Ptpn13protein tyrosine phosphatase, non-receptor type 13ENCODES a protein that exhibits phosphatidylinositol 3-kinase regulatory subunit binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN cellular response to toxic substance; negative regulation of excitatory synapse assembly; negative 1464128416587238Rat193descriptiongene, protein-coding, VALIDATED [RefSeq]
1303020Rnase6ribonuclease A family member 6ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN antibacterial humoral response (ortholog); antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH liver disease (ortholog152682789626830807Rat88descriptiongene, protein-coding, VALIDATED [RefSeq]
628815Slc17a3solute carrier family 17 member 3ENCODES a protein that exhibits efflux transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN organic anion transport (ortholog); urate metabolic process (ort174169867941729057Rat132descriptiongene, protein-coding, PROVISIONAL [RefSeq]
628885Slc22a19solute carrier family 22, member 19ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); transmembrane transporter activity (ortholog); INVOLVED IN response to molecule of fungal origin; sodium-independent organic anion transport; organic anion transport (ortholog);1214339594214394681Rat69descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1309495Srsf9serine and arginine rich splicing factor 9ENCODES a protein that exhibits protein domain specific binding (ortholog); INVOLVED IN response to alkaloid; response to toxic substance; negative regulation of mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Expe124693894846945213Rat94descriptiongene, protein-coding, VALIDATED [RefSeq]
3679St8sia1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENCODES a protein that exhibits sialyltransferase activity; alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN ganglioside metabolic pathway; glo4177513966177651553Rat85descriptiongene, protein-coding, VALIDATED [RefSeq]
1562552Sting1stimulator of interferon response cGAMP interactor 1ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding; cyclic-di-GMP binding (ortholog); identical protein binding (ortholog); INVOLVED IN positive regulation of type I interferon production; activation of innate immune response (ortholog); antiviral innate immune response (ortholog); ASSOCIA182760619627612544Rat310descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1564460Tlr11toll-like receptor 11INVOLVED IN response to bacterium (ortholog); PARTICIPATES IN toxoplasmosis pathway; ASSOCIATED WITH membranoproliferative glomerulonephritis (ortholog); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A; 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ort152601898726023426Rat23descriptiongene, protein-coding, VALIDATED [RefSeq]
1566403Tmem181transmembrane protein 181ENCODES a protein that exhibits toxic substance binding (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole14923592349290244Rat55descriptiongene, protein-coding, PROVISIONAL [RefSeq]