Antxrl1 (ANTXR like 1) - Rat Genome Database

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Gene: Antxrl1 (ANTXR like 1) Rattus norvegicus
Analyze
Symbol: Antxrl1 (Ensembl: Antxrl)
Name: ANTXR like 1 (Ensembl:ANTXR like)
RGD ID: 1563190
Description: Orthologous to human ANTXRL (ANTXR like); INTERACTS WITH atrazine; bisphenol A; 1,2-dimethylhydrazine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anthrax toxin receptor-like; ANTXR like; Antxrl; LOC364513; RGD1563190; similar to hypothetical protein 4933430J11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,369,046 - 9,393,569 (+)NCBIGRCr8
mRatBN7.2169,362,211 - 9,387,762 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,363,580 - 9,387,329 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01610,383,943 - 10,410,327 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,384,011 - 10,407,181 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,704,278 - 8,727,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,679,296 - 9,705,445 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera165,822,060 - 5,847,311 (-)NCBICelera
Cytogenetic Map16p15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Antxrl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8169,369,046 - 9,393,569 (+)NCBIGRCr8
mRatBN7.2169,362,211 - 9,387,762 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl169,363,580 - 9,387,329 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01610,383,943 - 10,410,327 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1610,384,011 - 10,407,181 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,704,278 - 8,727,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4169,679,296 - 9,705,445 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera165,822,060 - 5,847,311 (-)NCBICelera
Cytogenetic Map16p15NCBI
ANTXRL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381046,286,092 - 46,330,129 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1046,286,345 - 46,330,207 (+)EnsemblGRCh38hg38GRCh38
GRCh371047,658,233 - 47,701,365 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361047,128,240 - 47,171,452 (+)NCBINCBI36Build 36hg18NCBI36
Celera1042,590,783 - 42,634,004 (-)NCBICelera
Cytogenetic Map10q11.22NCBI
HuRef1045,383,032 - 45,425,496 (-)NCBIHuRef
CHM1_11047,727,151 - 47,770,359 (+)NCBICHM1_1
T2T-CHM13v2.01047,171,217 - 47,216,165 (+)NCBIT2T-CHM13v2.0
Antxrl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391433,774,625 - 33,798,280 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1433,774,664 - 33,798,362 (+)EnsemblGRCm39 Ensembl
GRCm381434,052,668 - 34,076,323 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1434,052,707 - 34,076,405 (+)EnsemblGRCm38mm10GRCm38
MGSCv371434,866,656 - 34,889,185 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361432,882,562 - 32,905,091 (+)NCBIMGSCv36mm8
Celera1430,316,169 - 30,338,569 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1420.8NCBI
Antxrl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555106,297,209 - 6,343,033 (-)NCBIChiLan1.0ChiLan1.0
ANTXRL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2859,642,115 - 59,685,896 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11059,647,432 - 59,691,231 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01043,928,771 - 43,971,522 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11047,460,947 - 47,503,899 (+)NCBIpanpan1.1PanPan1.1panPan2
ANTXRL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1434,885,718 - 34,916,651 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl434,885,962 - 34,954,104 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha434,875,827 - 34,886,593 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0435,244,823 - 35,275,949 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl435,245,444 - 35,313,417 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1435,077,454 - 35,108,554 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0435,259,213 - 35,290,288 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0435,765,659 - 35,782,376 (-)NCBIUU_Cfam_GSD_1.0
LOC110598553
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721381,462,158 - 81,487,003 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365547,472,740 - 7,489,155 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANTXRL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11488,342,134 - 88,380,019 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21495,827,057 - 95,865,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Antxrl1
154 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:91
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000031473
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357403Slep4Serum leptin concentration QTL 43.91blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1619639137Rat
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
2301406Kidm39Kidney mass QTL 390.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)16285170915884239Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
737825Alc13Alcohol consumption QTL 134.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760916039848Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
61372Bp40Blood pressure QTL 402.2blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)16422773017696785Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system renal system reproductive system respiratory system
High
Medium 5
Low 2
Below cutoff 2 1 3 2 3 2 3 1 2 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000084818   ⟹   ENSRNOP00000074258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl169,363,580 - 9,387,329 (+)Ensembl
Rnor_6.0 Ensembl1610,384,011 - 10,407,181 (+)Ensembl
RefSeq Acc Id: XM_039094946   ⟹   XP_038950874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8169,369,046 - 9,393,569 (+)NCBI
mRatBN7.2169,362,211 - 9,387,757 (+)NCBI
RefSeq Acc Id: XM_039094947   ⟹   XP_038950875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8169,372,822 - 9,393,569 (+)NCBI
mRatBN7.2169,366,578 - 9,387,762 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038950874 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950875 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL88891 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074258
  ENSRNOP00000074258.2
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000074258   ⟸   ENSRNOT00000084818
RefSeq Acc Id: XP_038950874   ⟸   XM_039094946
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K7L7 (UniProtKB/TrEMBL),   A6KFT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950875   ⟸   XM_039094947
- Peptide Label: isoform X2
Protein Domains
VWFA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7L7-F1-model_v2 AlphaFold A0A0G2K7L7 1-608 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563190 AgrOrtholog
BioCyc Gene G2FUF-12078 BioCyc
Ensembl Genes ENSRNOG00000052152 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084818.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro Anthrax_toxin_rcpt_extracel UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene 364513 ENTREZGENE
PANTHER ANTHRAX TOXIN RECEPTOR UniProtKB/TrEMBL
  ANTHRAX TOXIN RECEPTOR-LIKE UniProtKB/TrEMBL
Pfam Anth_Ig UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
PhenoGen Antxrl1 PhenoGen
PROSITE VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000052152 RatGTEx
SMART VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A0G2K7L7 ENTREZGENE, UniProtKB/TrEMBL
  A6KFT3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-11 Antxrl1  ANTXR like 1  Antxrl  ANTXR like  Name and Symbol changed 629549 APPROVED
2018-05-18 Antxrl  ANTXR like  Antxrl  anthrax toxin receptor-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Antxrl  anthrax toxin receptor-like  RGD1563190_predicted  similar to hypothetical protein 4933430J11 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563190_predicted  similar to hypothetical protein 4933430J11 (predicted)  LOC364513  similar to hypothetical protein 4933430J11  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC364513  similar to hypothetical protein 4933430J11      Symbol and Name status set to provisional 70820 PROVISIONAL