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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal response to myocardial ischemic injury
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Accession:MP:0031215 term browser browse the term
Definition:altered response to lack of adequate blood flow, due to trauma or disease, to support the normal functioning of the myocardium
Synonyms:exact_synonym: abnormal response to myocardial ischaemic injury;   altered response to myocardial ischaemic injury;   altered response to myocardial ischemic injury


show annotations for term's descendants           Sort by:
abnormal response to myocardial ischemic injury term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grem2 gremlin 2, DAN family BMP antagonist IAGP MGI PMID:27283840 NCBI chr 1:174,661,352...174,749,386
Ensembl chr 1:174,661,351...174,749,385 		JBrowse link
decreased myocardial infarct size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor IAGP MGI PMID:19038262 PMID:24132636 PMID:26119742 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Adora3 adenosine A3 receptor IAGP MGI PMID:11273734 NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242 		JBrowse link
G Alkbh7 alkB homolog 7 IAGP MGI PMID:32795389 NCBI chr17:57,304,339...57,306,340
Ensembl chr17:57,304,339...57,306,322 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:15031124 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Bbc3 BCL2 binding component 3 IAGP MGI PMID:16399862 NCBI chr 7:16,042,307...16,052,130
Ensembl chr 7:16,042,318...16,052,130 		JBrowse link
G Becn1 beclin 1, autophagy related IAGP MGI PMID:21737790 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:12437588 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Dusp6 dual specificity phosphatase 6 IAGP MGI PMID:18753132 NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IAGP MGI PMID:21270129 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IAGP MGI PMID:16246361 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Flt1 FMS-like tyrosine kinase 1 IAGP MGI PMID:22753193 NCBI chr 5:147,498,414...147,663,419
Ensembl chr 5:147,498,414...147,662,821 		JBrowse link
G Gnai2 G protein subunit alpha i2 IAGP MGI PMID:24899231 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IAGP MGI PMID:21737790 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:18312674 PMID:22753193 PMID:24899231 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Ldlr low density lipoprotein receptor IAGP MGI PMID:15031124 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 IAGP MGI PMID:12593847 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380 		JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 IAGP MGI PMID:15623425 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563 		JBrowse link
G Masp2 MBL associated serine protease 2 IAGP MGI PMID:21502512 NCBI chr 4:148,679,079...148,699,939
Ensembl chr 4:148,687,011...148,699,956 		JBrowse link
G Mcu mitochondrial calcium uniporter IAGP MGI PMID:26119742 NCBI chr10:59,282,806...59,453,231
Ensembl chr10:59,282,806...59,452,514 		JBrowse link
G Mff mitochondrial fission factor IAGP MGI PMID:28288978 NCBI chr 1:82,702,599...82,730,111
Ensembl chr 1:82,702,611...82,730,115 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:12031700 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow IAGP MGI PMID:18312674 PMID:21270129 NCBI chr 5:122,230,787...122,251,536
Ensembl chr 5:122,239,014...122,251,535 		JBrowse link
G Ngfr nerve growth factor receptor (TNFR superfamily, member 16) IAGP MGI PMID:23091165 NCBI chr11:95,459,644...95,478,524
Ensembl chr11:95,459,644...95,478,561 		JBrowse link
G Npr1 natriuretic peptide receptor 1 IAGP MGI PMID:11457873 NCBI chr 3:90,357,898...90,373,235
Ensembl chr 3:90,357,898...90,373,173 		JBrowse link
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 IAGP MGI PMID:18022184 NCBI chr 6:129,456,113...129,484,312
Ensembl chr 6:129,462,207...129,484,128 		JBrowse link
G Pla2g10 phospholipase A2, group X IAGP MGI PMID:18506007 NCBI chr16:13,532,921...13,548,863
Ensembl chr16:13,532,921...13,548,847 		JBrowse link
G Pla2g5 phospholipase A2, group V IAGP MGI PMID:21169294 NCBI chr 4:138,526,558...138,590,784
Ensembl chr 4:138,526,555...138,590,793 		JBrowse link
G Ppif peptidylprolyl isomerase F (cyclophilin F) IAGP MGI PMID:15800626 PMID:15800627 NCBI chr14:25,693,998...25,700,892
Ensembl chr14:25,694,578...25,700,892 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:19038262 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 IAGP MGI PMID:36495058 NCBI chr11:120,527,591...120,534,602
Ensembl chr11:120,526,538...120,534,595 		JBrowse link
G Sstr2 somatostatin receptor 2 IAGP MGI PMID:15601946 NCBI chr11:113,510,153...113,516,854
Ensembl chr11:113,510,168...113,516,854 		JBrowse link
G Tmem11 transmembrane protein 11 IAGP MGI PMID:37286744 NCBI chr11:60,755,278...60,769,864
Ensembl chr11:60,755,278...60,770,098 		JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon IAGP MGI PMID:34728372
G Tnni3k TNNI3 interacting kinase IAGP MGI PMID:24132636 NCBI chr 3:154,491,928...154,761,044
Ensembl chr 3:154,491,928...154,761,044 		JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:21737790 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Vwf Von Willebrand factor IAGP MGI PMID:19182208 NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642 		JBrowse link
decreased susceptibility to myocardial ischemic injury term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pycr1 pyrroline-5-carboxylate reductase 1 IAGP MGI PMID:36495058 NCBI chr11:120,527,591...120,534,602
Ensembl chr11:120,526,538...120,534,595 		JBrowse link
G Tmem11 transmembrane protein 11 IAGP MGI PMID:37286744 NCBI chr11:60,755,278...60,769,864
Ensembl chr11:60,755,278...60,770,098 		JBrowse link
G Vgll3 vestigial like family member 3 IAGP MGI PMID:36754961 NCBI chr16:65,612,075...65,663,254
Ensembl chr16:65,612,143...65,663,254 		JBrowse link
increased myocardial infarct size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor IAGP MGI PMID:34831084 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 IAGP MGI PMID:15933268 NCBI chr  X:47,563,821...47,602,440
Ensembl chr  X:47,563,821...47,602,440 		JBrowse link
G Alkbh7 alkB homolog 7 IAGP MGI PMID:32795389 NCBI chr17:57,304,339...57,306,340
Ensembl chr17:57,304,339...57,306,322 		JBrowse link
G Apod apolipoprotein D IAGP MGI PMID:24082102 NCBI chr16:31,115,010...31,133,626
Ensembl chr16:31,115,010...31,133,626 		JBrowse link
G Becn1 beclin 1, autophagy related IAGP MGI PMID:21737790 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IAGP MGI PMID:24983315 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 IAGP MGI PMID:27840305 NCBI chr 1:165,591,327...165,602,878
Ensembl chr 1:165,591,315...165,602,877 		JBrowse link
G Ddt D-dopachrome tautomerase IAGP MGI PMID:24983315 NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248 		JBrowse link
G Fgf2 fibroblast growth factor 2 IAGP MGI PMID:17872976 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257 		JBrowse link
G Gdf15 growth differentiation factor 15 IAGP MGI PMID:16397141 NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta IAGP MGI PMID:21737790 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446 		JBrowse link
G Hmox1 heme oxygenase 1 IAGP MGI PMID:11273999 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217 		JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:11406467 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:16467148 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Laptm4b lysosomal-associated protein transmembrane 4B IAGP MGI PMID:32693673 NCBI chr15:34,238,279...34,284,448
Ensembl chr15:34,238,174...34,284,448 		JBrowse link
G Lims1 LIM and senescent cell antigen-like domains 1 IAGP MGI PMID:19652092 NCBI chr10:58,159,164...58,260,513
Ensembl chr10:58,159,288...58,260,513 		JBrowse link
G Lims2 LIM and senescent cell antigen like domains 2 IAGP MGI PMID:19652092 NCBI chr18:32,055,346...32,091,673
Ensembl chr18:32,055,343...32,091,672 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 IAGP MGI PMID:15096454 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) IAGP MGI PMID:24983315 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Mir214 microRNA 214 IAGP MGI PMID:22426211 NCBI chr 1:162,050,937...162,051,046
Ensembl chr 1:162,050,937...162,051,046 		JBrowse link
G Mydgf myeloid derived growth factor IAGP MGI PMID:25581518 NCBI chr17:56,483,541...56,490,920
Ensembl chr17:56,482,744...56,490,920 		JBrowse link
G Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) IAGP MGI PMID:16505176 NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible IAGP MGI PMID:11406467 PMID:14747298 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Nt5e 5' nucleotidase, ecto IAGP MGI PMID:17353435 NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145 		JBrowse link
G Pakap paralemmin A kinase anchor protein IAGP MGI PMID:34831084 NCBI chr 4:57,434,475...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984 		JBrowse link
G Pkn1 protein kinase N1 IAGP MGI PMID:29045568 NCBI chr 8:84,393,162...84,425,819
Ensembl chr 8:84,393,165...84,425,808 		JBrowse link
G Prkce protein kinase C, epsilon IAGP MGI PMID:12160964 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:29969932 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase IAGP MGI PMID:21178975 NCBI chr19:33,115,140...33,369,695
Ensembl chr19:33,115,147...33,369,665 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:10679476 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IAGP MGI PMID:12223448 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Tgm2 transglutaminase 2, C polypeptide IAGP MGI PMID:16528383 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356 		JBrowse link
G Thbd thrombomodulin IAGP MGI PMID:12208873 NCBI chr 2:148,246,391...148,250,108
Ensembl chr 2:148,246,386...148,250,108 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IAGP MGI PMID:10779546 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b IAGP MGI PMID:10779546 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440 		JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:21737790 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604 		JBrowse link
G Yap1 yes-associated protein 1 IAGP MGI PMID:23918388 NCBI chr 9:7,932,000...8,004,890
Ensembl chr 9:7,932,000...8,004,597 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta IAGP MGI PMID:17145769 NCBI chr12:21,440,330...21,467,437
Ensembl chr12:21,440,072...21,467,638 		JBrowse link
increased susceptibility to myocardial ischemic injury term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor IAGP MGI PMID:34831084 NCBI chr19:31,846,156...31,929,765
Ensembl chr19:31,846,164...31,926,395 		JBrowse link
G Abi3bp ABI family member 3 binding protein IAGP MGI PMID:25296984 NCBI chr16:56,298,179...56,510,498
Ensembl chr16:56,298,241...56,510,498 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IAGP MGI PMID:24983315 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Cirpil cardiac ischemia reperfusion associated p53 interacting lncRNA IAGP MGI PMID:35851102 NCBI chr 5:111,638,717...111,642,637
Ensembl chr 5:111,638,797...111,640,250 		JBrowse link
G Ddt D-dopachrome tautomerase IAGP MGI PMID:24983315 NCBI chr10:75,607,067...75,609,208
Ensembl chr10:75,607,064...75,609,248 		JBrowse link
G Fbxw5 F-box and WD-40 domain protein 5 IAGP MGI PMID:32971071 NCBI chr 2:25,390,762...25,395,482
Ensembl chr 2:25,390,762...25,395,483 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) IAGP MGI PMID:24983315 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Pakap paralemmin A kinase anchor protein IAGP MGI PMID:34831084 NCBI chr 4:57,434,475...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984
Ensembl chr 4:57,717,657...57,896,984 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:29969932 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16756
    homeostasis/metabolism phenotype 7731
      abnormal response to injury 759
        abnormal response to cardiac infarction 112
          abnormal response to myocardial ischemic injury 73
            decreased susceptibility to myocardial ischemic injury + 37
            increased susceptibility to myocardial ischemic injury + 41
paths to the root