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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
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Accession:GO:0070424 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of a nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (NLR) pathway.
Synonyms:narrow_synonym: regulation of NOD signaling pathway;   regulation of nucleotide-binding oligomerization domain containing signaling pathway;   regulation of nucleotide-binding oligomerization domain containing signalling pathway


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regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a2 solute carrier family 15 member 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192142|PMID:29784761)		 UniProt
RGD		 PMID:29784761 GO_REF:0000024 MGI:6192142 NCBI chr11:64,014,182...64,043,228
Ensembl chr11:64,014,182...64,043,225 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6192142|PMID:29784761)		 UniProt
RGD		 PMID:29784761 GO_REF:0000024 MGI:6192142 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3777503|PMID:18342009) RGD PMID:18342009 MGI:3777503 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (PMID:16203728)
(MGI:5640951|PMID:16203728)		 RGD PMID:16203728 MGI:5640951 NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106)
(MGI:5640942|PMID:23991106)		 RGD PMID:23991106 MGI:5640942 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3777503|PMID:18342009) RGD PMID:18342009 MGI:3777503 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) RGD PMID:28656966 NCBI chr 9:1,353,308...1,354,496
Ensembl chr 9:1,353,306...1,354,584 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:6278628|PMID:21277849), (MGI:6450424|PMID:19570976)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19570976 PMID:21277849 GO_REF:0000024 GO_REF:0000107 MGI:6278628 MGI:6450424 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Slc46a2 solute carrier family 46, member 2 involved_in ISO (PMID:28539433) RGD PMID:28539433 NCBI chr 5:74,800,226...74,808,128
Ensembl chr 5:74,800,226...74,808,128 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Nagk N-acetylglucosamine kinase involved_in ISS
ISO		 GO_REF:0000024
(PMID:36002575)
(MGI:7484284|PMID:36002575)		 UniProt
RGD		 PMID:36002575 GO_REF:0000024 MGI:7484284 NCBI chr 4:116,281,179...116,293,870
Ensembl chr 4:116,281,328...116,313,137 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) RGD PMID:23892723 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5571205|PMID:24695226)		 UniProt
RGD		 PMID:24695226 GO_REF:0000024 MGI:5571205 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5571205|PMID:24695226)		 Ensembl
UniProt
RGD		 PMID:24695226 GO_REF:0000024 GO_REF:0000107 MGI:5571205 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:23892723) RGD PMID:23892723 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      signal transduction 7209
        intracellular receptor signaling pathway 379
          cytoplasmic pattern recognition receptor signaling pathway 170
            nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 24
              regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 13
                negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 4
                positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 8
                regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway + 5
                regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway + 11
Path 2
Term Annotations click to browse term
  biological_process 20413
    response to stimulus 10919
      response to external stimulus 2746
        response to external biotic stimulus 1854
          response to other organism 1850
            defense response to other organism 1305
              defense response to symbiont 1169
                innate immune response 996
                  regulation of innate immune response 458
                    positive regulation of innate immune response 375
                      activation of innate immune response 304
                        innate immune response-activating signaling pathway 278
                          pattern recognition receptor signaling pathway 266
                            cytoplasmic pattern recognition receptor signaling pathway 170
                              nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 24
                                regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 13
                                  negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 4
                                  positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway + 8
                                  regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway + 5
                                  regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway + 11
paths to the root