ONTOLOGY REPORT - ANNOTATIONS
Term: positive regulation of innate immune response
Accession: GO:0045089
browse the term
Definition: Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
Synonyms: exact_synonym: up regulation of innate immune response; upregulation of innate immune response
narrow_synonym: stimulation of innate immune response
positive regulation of innate immune response
G
Card9
caspase recruitment domain family, member 9
ISO
3
4,524,781
4,533,412
RGD:1624291
RGD
G
Ereg
epiregulin
ISO
14
18,521,069
18,534,844
RGD:1624291
RGD
G
Ereg
epiregulin
ISS
14
18,521,069
18,534,844
RGD:1600115
UniProtKB
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISO
19
19,662,337
19,697,341
RGD:1624291
RGD
G
Plscr1
phospholipid scramblase 1
ISO
8
97,206,388
97,226,725
RGD:1624291
RGD
G
Plscr1
phospholipid scramblase 1
ISO
8
97,206,388
97,226,725
RGD:1624291
RGD
G
Plscr1
phospholipid scramblase 1
ISS
8
97,206,388
97,226,725
RGD:1600115
UniProtKB
G
Plscr1
phospholipid scramblase 1
IEA
8
97,206,388
97,226,725
RGD:1600115
ENSEMBL
G
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
IEA
7
21,167,374
21,271,601
RGD:1600115
ENSEMBL
G
Polr3b
polymerase (RNA) III (DNA directed) polypeptide B
ISO
7
21,167,374
21,271,601
RGD:1624291
RGD
G
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
ISO
2
191,511,970
191,527,849
RGD:1624291
RGD
G
Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
ISS
2
191,511,970
191,527,849
RGD:1600115
UniProtKB
G
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
ISO
15
50,838,153
50,842,822
RGD:1624291
RGD
G
Polr3d
polymerase (RNA) III (DNA directed) polypeptide D
IEA
15
50,838,153
50,842,822
RGD:1600115
ENSEMBL
G
Polr3f
polymerase (RNA) III (DNA directed) polypeptide F
ISO
3
133,074,263
133,090,633
RGD:1624291
RGD
G
Polr3g
polymerase (RNA) III (DNA directed) polypeptide G
ISO
2
9,763,378
9,804,285
RGD:1624291
RGD
G
Polr3g
polymerase (RNA) III (DNA directed) polypeptide G
ISO
2
9,763,378
9,804,285
RGD:1624291
RGD
G
Polr3g
polymerase (RNA) III (DNA directed) polypeptide G
IEA
2
9,763,378
9,804,285
RGD:1600115
ENSEMBL
G
Sh2d1b
SH2 domain containing 1B
ISO
13
86,096,465
86,126,881
RGD:1624291
RGD
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
G
Tlr8
toll-like receptor 8
ISO
RGD:1624291
RGD
activation of innate immune response
G
Aim2
absent in melanoma 2
ISO
13
89,631,797
89,640,265
RGD:1624291
RGD
G
Aim2
absent in melanoma 2
ISO
13
89,631,797
89,640,265
RGD:1624291
RGD
G
Aim2
absent in melanoma 2
ISO
13
89,631,797
89,640,265
RGD:1624291
RGD
G
Aim2
absent in melanoma 2
ISO
13
89,631,797
89,640,265
RGD:1624291
RGD
G
Mavs
mitochondrial antiviral signaling protein
ISO
3
118,938,433
118,953,081
RGD:1624291
RGD
G
Mavs
mitochondrial antiviral signaling protein
IEA
3
118,938,433
118,953,081
RGD:1600115
ENSEMBL
G
Nlrc4
NLR family, CARD domain containing 4
ISS
6
20,934,595
20,953,654
RGD:1600115
UniProtKB
G
Nlrc4
NLR family, CARD domain containing 4
ISO
6
20,934,595
20,953,654
RGD:1624291
RGD
G
Pycard
PYD and CARD domain containing
IEA
1
187,276,089
187,277,122
RGD:1600115
ENSEMBL
G
Pycard
PYD and CARD domain containing
ISO
1
187,276,089
187,277,122
RGD:1624291
RGD
G
Pycard
PYD and CARD domain containing
ISO
1
187,276,089
187,277,122
RGD:1624291
RGD
G
Sin3a
SIN3 transcription regulator homolog A (yeast)
IEA
8
60,832,595
60,884,764
RGD:1600115
ENSEMBL
G
Sin3a
SIN3 transcription regulator homolog A (yeast)
ISO
8
60,832,595
60,884,764
RGD:1624291
RGD
G
Tbk1
TANK-binding kinase 1
ISO
7
60,863,099
60,896,131
RGD:1624291
RGD
G
Tbk1
TANK-binding kinase 1
IEA
7
60,863,099
60,896,131
RGD:1600115
ENSEMBL
G
Tlr4
toll-like receptor 4
ISO
5
83,564,100
83,577,735
RGD:1624291
RGD
G
Tmem173
transmembrane protein 173
ISO
18
28,355,029
28,357,171
RGD:1624291
RGD
G
Tmem173
transmembrane protein 173
IEA
18
28,355,029
28,357,171
RGD:1600115
ENSEMBL
G
Trim5
tripartite motif-containing 5
ISO
1
162,096,439
162,113,409
RGD:1624291
RGD
activation of MAPK activity involved in innate immune response
G
Adam8
ADAM metallopeptidase domain 8
ISO
1
199,780,772
199,791,855
RGD:1624291
RGD
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISO
19
19,662,337
19,697,341
RGD:1624291
RGD
cell surface pattern recognition receptor signaling pathway
G
Clec7a
C-type lectin domain family 7, member A
ISO
4
166,723,515
166,734,681
RGD:1624291
RGD
G
Tlr2
toll-like receptor 2
ISO
2
175,607,990
175,613,992
RGD:1624291
RGD
G
Tlr2
toll-like receptor 2
IEA
2
175,607,990
175,613,992
RGD:1600115
ENSEMBL
innate immune response-activating signal transduction
G
Tlr4
toll-like receptor 4
IMP
5
83,564,100
83,577,735
RGD:2312509
RGD
MyD88-dependent toll-like receptor signaling pathway
G
Hspd1
heat shock protein 1 (chaperonin)
ISO
9
53,884,193
53,895,043
RGD:1624291
RGD
G
Myd88
myeloid differentiation primary response 88
ISO
8
124,299,729
124,303,798
RGD:1624291
RGD
G
Myd88
myeloid differentiation primary response 88
ISO
8
124,299,729
124,303,798
RGD:1624291
RGD
G
Myd88
myeloid differentiation primary response 88
ISO
8
124,299,729
124,303,798
RGD:1624291
RGD
G
Myd88
myeloid differentiation primary response 88
IEA
8
124,299,729
124,303,798
RGD:1600115
ENSEMBL
G
Tlr10
toll-like receptor 10
IEA
14
46,139,461
46,141,896
RGD:1600115
InterPro
G
Tlr11
toll-like receptor 11
IEA
15
26,073,335
26,076,214
RGD:1600115
InterPro
G
Tlr13
toll-like receptor 13
ISO
X
94,289,915
94,293,710
RGD:1624291
RGD
G
Tlr2
toll-like receptor 2
ISO
2
175,607,990
175,613,992
RGD:1624291
RGD
G
Tlr2
toll-like receptor 2
IEA
2
175,607,990
175,613,992
RGD:1600115
ENSEMBL
G
Tlr4
toll-like receptor 4
IEA
5
83,564,100
83,577,735
RGD:1600115
InterPro
G
Tlr5
toll-like receptor 5
IEA
13
99,025,501
99,029,755
RGD:1600115
InterPro
G
Tlr6
toll-like receptor 6
IEA
14
46,089,365
46,100,687
RGD:1600115
InterPro
G
Tlr7
toll-like receptor 7
IEA
X
47,330,737
47,356,841
RGD:1600115
InterPro
G
Tlr8
toll-like receptor 8
IEA
RGD:1600115
InterPro
G
Tlr9
toll-like receptor 9
IEA
RGD:1600115
InterPro
G
Tnip1
TNFAIP3 interacting protein 1
ISO
10
40,319,735
40,366,764
RGD:1624291
RGD
MyD88-independent toll-like receptor signaling pathway
G
Tlr3
toll-like receptor 3
IEA
16
50,112,910
50,126,371
RGD:1600115
InterPro
G
Tnip3
TNFAIP3 interacting protein 3
ISO
4
95,130,822
95,170,426
RGD:1624291
RGD
G
Tnip3
TNFAIP3 interacting protein 3
IEA
4
95,130,822
95,170,426
RGD:1600115
ENSEMBL
negative regulation of MDA-5 signaling pathway
G
C1qbp
complement component 1, q subcomponent binding protein
ISS
10
57,881,783
57,886,434
RGD:1600115
UniProtKB
G
C1qbp
complement component 1, q subcomponent binding protein
ISO
10
57,881,783
57,886,434
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
IEA
10
89,630,145
89,641,311
RGD:1600115
ENSEMBL
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
negative regulation of RIG-I signaling pathway
G
C1qbp
complement component 1, q subcomponent binding protein
ISS
10
57,881,783
57,886,434
RGD:1600115
UniProtKB
G
C1qbp
complement component 1, q subcomponent binding protein
ISO
10
57,881,783
57,886,434
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
IEA
10
89,630,145
89,641,311
RGD:1600115
ENSEMBL
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
negative regulation of toll-like receptor 2 signaling pathway
G
Lyn
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
ISO
5
16,933,111
17,054,564
RGD:1624291
RGD
G
Lyn
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
ISS
5
16,933,111
17,054,564
RGD:1600115
UniProtKB
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISO
19
19,662,337
19,697,341
RGD:1624291
RGD
G
Nod2
nucleotide-binding oligomerization domain containing 2
IEA
19
19,662,337
19,697,341
RGD:1600115
ENSEMBL
negative regulation of toll-like receptor 3 signaling pathway
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
ISO
2
25,886,177
25,899,128
RGD:1624291
RGD
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
IEA
2
25,886,177
25,899,128
RGD:1600115
ENSEMBL
negative regulation of toll-like receptor 4 signaling pathway
G
Dab2ip
DAB2 interacting protein
ISO
3
14,667,700
14,840,625
RGD:1624291
RGD
G
Dab2ip
DAB2 interacting protein
ISS
3
14,667,700
14,840,625
RGD:1600115
UniProtKB
G
Lyn
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
ISO
5
16,933,111
17,054,564
RGD:1624291
RGD
G
Lyn
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
ISS
5
16,933,111
17,054,564
RGD:1600115
UniProtKB
G
Nr1d1
nuclear receptor subfamily 1, group D, member 1
ISO
10
87,541,246
87,548,186
RGD:1624291
RGD
G
Nr1d1
nuclear receptor subfamily 1, group D, member 1
IEA
10
87,541,246
87,548,186
RGD:1600115
ENSEMBL
G
Rab7b
Rab7b, member RAS oncogene family
IEA
13
44,620,063
44,636,864
RGD:1600115
ENSEMBL
negative regulation of toll-like receptor 9 signaling pathway
G
Rab7b
Rab7b, member RAS oncogene family
IEA
13
44,620,063
44,636,864
RGD:1600115
ENSEMBL
negative regulation of toll-like receptor signaling pathway
G
Arrb2
arrestin, beta 2
ISO
10
57,244,071
57,284,166
RGD:1624291
RGD
G
Arrb2
arrestin, beta 2
IEA
10
57,244,071
57,284,166
RGD:1600115
ENSEMBL
G
Cactin
cactin, spliceosome C complex subunit
ISO
7
9,875,757
9,880,563
RGD:1624291
RGD
G
Irak3
interleukin-1 receptor-associated kinase 3
ISO
7
59,408,198
59,467,821
RGD:1624291
RGD
G
Irak3
interleukin-1 receptor-associated kinase 3
IEA
7
59,408,198
59,467,821
RGD:1600115
ENSEMBL
G
Irf4
interferon regulatory factor 4
ISO
17
40,170,409
40,189,976
RGD:1624291
RGD
G
Irf4
interferon regulatory factor 4
IEA
17
40,170,409
40,189,976
RGD:1600115
ENSEMBL
G
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ISO
20
3,629,246
3,644,222
RGD:1624291
RGD
G
Nfkbil1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
ISS
20
3,629,246
3,644,222
RGD:1600115
UniProtKB
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
ISO
10
13,329,708
13,394,080
RGD:1624291
RGD
G
Pdpk1
3-phosphoinositide dependent protein kinase-1
IEA
10
13,329,708
13,394,080
RGD:1600115
ENSEMBL
G
Tlr9
toll-like receptor 9
ISO
RGD:1624291
RGD
G
Tyro3
TYRO3 protein tyrosine kinase
ISO
3
106,309,671
106,328,607
RGD:1624291
RGD
G
Tyro3
TYRO3 protein tyrosine kinase
IEA
3
106,309,671
106,328,607
RGD:1600115
ENSEMBL
G
Tyro3
TYRO3 protein tyrosine kinase
ISS
3
106,309,671
106,328,607
RGD:1600115
UniProtKB
nucleotide-binding oligomerization domain containing 1 signaling pathway
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ISO
6
75,729,302
75,732,475
RGD:1624291
RGD
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
IEA
6
75,729,302
75,732,475
RGD:1600115
ENSEMBL
G
Ripk2
receptor-interacting serine-threonine kinase 2
ISO
5
30,714,817
30,745,941
RGD:1624291
RGD
G
Ripk2
receptor-interacting serine-threonine kinase 2
IEA
5
30,714,817
30,745,941
RGD:1600115
ENSEMBL
nucleotide-binding oligomerization domain containing 2 signaling pathway
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ISO
6
75,729,302
75,732,475
RGD:1624291
RGD
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
IEA
6
75,729,302
75,732,475
RGD:1600115
ENSEMBL
G
Nod2
nucleotide-binding oligomerization domain containing 2
IEA
19
19,662,337
19,697,341
RGD:1600115
ENSEMBL
G
Nod2
nucleotide-binding oligomerization domain containing 2
ISO
19
19,662,337
19,697,341
RGD:1624291
RGD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
ISO
1
208,262,669
208,273,148
RGD:1624291
RGD
G
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
IEA
1
208,262,669
208,273,148
RGD:1600115
ENSEMBL
G
Ripk2
receptor-interacting serine-threonine kinase 2
ISO
5
30,714,817
30,745,941
RGD:1624291
RGD
G
Ripk2
receptor-interacting serine-threonine kinase 2
IEA
5
30,714,817
30,745,941
RGD:1600115
ENSEMBL
pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response
G
Nod2
nucleotide-binding oligomerization domain containing 2
IDA
19
19,662,337
19,697,341
RGD:1643119
RGD
G
Tlr1
toll-like receptor 1
IDA
RGD:1643119
RGD
G
Tlr2
toll-like receptor 2
IDA
2
175,607,990
175,613,992
RGD:1643119
RGD
G
Tlr3
toll-like receptor 3
IDA
16
50,112,910
50,126,371
RGD:1643119
RGD
G
Tlr4
toll-like receptor 4
IDA
5
83,564,100
83,577,735
RGD:1643119
RGD
G
Tlr6
toll-like receptor 6
IDA
14
46,089,365
46,100,687
RGD:1643119
RGD
G
Tlr7
toll-like receptor 7
IDA
X
47,330,737
47,356,841
RGD:1643119
RGD
G
Tlr8
toll-like receptor 8
IDA
RGD:1643119
RGD
G
Tlr9
toll-like receptor 9
IDA
RGD:1643119
RGD
pattern recognition receptor signaling pathway
G
Cd36
CD36 molecule (thrombospondin receptor)
ISO
4
13,471,878
13,525,620
RGD:1624291
RGD
G
Clec7a
C-type lectin domain family 7, member A
ISO
4
166,723,515
166,734,681
RGD:1624291
RGD
G
Colec12
collectin sub-family member 12
ISO
18
996,297
1,188,288
RGD:1624291
RGD
G
Ptafr
platelet-activating factor receptor
ISO
5
152,565,687
152,587,342
RGD:1624291
RGD
G
Trim5
tripartite motif-containing 5
ISO
1
162,096,439
162,113,409
RGD:1624291
RGD
positive regulation of MDA-5 signaling pathway
G
Ddx60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
ISO
16
30,934,840
31,080,644
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
IEA
10
89,630,145
89,641,311
RGD:1600115
ENSEMBL
positive regulation of MyD88-dependent toll-like receptor signaling pathway
G
Mog
myelin oligodendrocyte glycoprotein
IMP
20
1,601,731
1,611,963
BHF-UCL
positive regulation of natural killer cell cytokine production
G
Gimap5
GTPase, IMAP family member 5
IMP
4
76,836,521
76,843,214
RGD:2303778
RGD
G
Il21
interleukin 21
ISO
2
123,774,331
123,781,697
RGD:1624291
RGD
G
Il21
interleukin 21
IEA
2
123,774,331
123,781,697
RGD:1600115
ENSEMBL
positive regulation of natural killer cell mediated cytotoxicity
G
Cadm1
cell adhesion molecule 1
ISO
8
50,765,645
51,108,962
RGD:1624291
RGD
G
Cadm1
cell adhesion molecule 1
ISO
8
50,765,645
51,108,962
RGD:1624291
RGD
G
Cadm1
cell adhesion molecule 1
ISS
8
50,765,645
51,108,962
RGD:1600115
UniProtKB
G
Cd226
CD226 molecule
ISO
18
86,064,574
86,157,909
RGD:1624291
RGD
G
Crtam
cytotoxic and regulatory T cell molecule
ISO
8
43,943,971
43,981,609
RGD:1624291
RGD
G
Crtam
cytotoxic and regulatory T cell molecule
ISO
8
43,943,971
43,981,609
RGD:1624291
RGD
G
Gimap5
GTPase, IMAP family member 5
IMP
4
76,836,521
76,843,214
RGD:2303778
RGD
G
Il12a
interleukin 12A
ISO
2
158,710,261
158,717,689
RGD:1624291
RGD
G
Il21
interleukin 21
ISO
2
123,774,331
123,781,697
RGD:1624291
RGD
G
Il21
interleukin 21
IEA
2
123,774,331
123,781,697
RGD:1600115
ENSEMBL
G
Klre1
killer cell lectin-like receptor, family E, member 1
ISO
4
166,857,685
166,864,221
RGD:1624291
RGD
G
Klre1
killer cell lectin-like receptor, family E, member 1
IEA
4
166,857,685
166,864,221
RGD:1600115
ENSEMBL
G
Klrk1
killer cell lectin-like receptor subfamily K, member 1
ISO
4
166,914,786
166,922,659
RGD:1624291
RGD
G
Klrk1
killer cell lectin-like receptor subfamily K, member 1
IEA
4
166,914,786
166,922,659
RGD:1600115
ENSEMBL
G
Lag3
lymphocyte-activation gene 3
ISO
4
161,031,506
161,039,255
RGD:1624291
RGD
G
Lag3
lymphocyte-activation gene 3
IEA
4
161,031,506
161,039,255
RGD:1600115
ENSEMBL
G
Ly49s3
Ly-49 stimulatory receptor 3
IDA
4
168,023,598
168,209,373
RGD:633264
RGD
G
Ncr3
natural cytotoxicity triggering receptor 3
IEA
20
3,701,807
3,707,278
RGD:1600115
ENSEMBL
G
PVR
poliovirus receptor
ISO
1
79,213,654
79,229,063
RGD:1624291
RGD
G
Pvrl2
poliovirus receptor-related 2
ISO
1
79,021,831
79,059,686
RGD:1624291
RGD
G
RT1-M3-1
RT1 class Ib, locus M3, gene 1
ISO
20
1,412,553
1,416,692
RGD:1624291
RGD
G
RT1-M3-1
RT1 class Ib, locus M3, gene 1
IEA
20
1,412,553
1,416,692
RGD:1600115
ENSEMBL
G
Sh2d1a
SH2 domain containing 1A
ISO
X
2,532,295
2,560,524
RGD:1624291
RGD
G
Sh2d1a
SH2 domain containing 1A
IEA
X
2,532,295
2,560,524
RGD:1600115
ENSEMBL
G
Stat5a
signal transducer and activator of transcription 5A
ISO
10
89,795,404
89,819,732
RGD:1624291
RGD
G
Stat5a
signal transducer and activator of transcription 5A
IEA
10
89,795,404
89,819,732
RGD:1600115
ENSEMBL
G
Stat5b
signal transducer and activator of transcription 5B
ISO
10
89,716,624
89,743,134
RGD:1624291
RGD
G
Stat5b
signal transducer and activator of transcription 5B
IEA
10
89,716,624
89,743,134
RGD:1600115
ENSEMBL
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
G
Cd226
CD226 molecule
ISO
18
86,064,574
86,157,909
RGD:1624291
RGD
G
Crtam
cytotoxic and regulatory T cell molecule
ISO
8
43,943,971
43,981,609
RGD:1624291
RGD
G
Crtam
cytotoxic and regulatory T cell molecule
IEA
8
43,943,971
43,981,609
RGD:1600115
ENSEMBL
G
Crtam
cytotoxic and regulatory T cell molecule
ISO
8
43,943,971
43,981,609
RGD:1624291
RGD
G
Il12a
interleukin 12A
ISO
2
158,710,261
158,717,689
RGD:1624291
RGD
G
Il12a
interleukin 12A
IEA
2
158,710,261
158,717,689
RGD:1600115
ENSEMBL
G
Il12b
interleukin 12B
ISO
10
29,558,955
29,568,331
RGD:1624291
RGD
G
PVR
poliovirus receptor
ISO
1
79,213,654
79,229,063
RGD:1624291
RGD
G
Pvrl2
poliovirus receptor-related 2
ISO
1
79,021,831
79,059,686
RGD:1624291
RGD
G
Pvrl2
poliovirus receptor-related 2
IEA
1
79,021,831
79,059,686
RGD:1600115
ENSEMBL
positive regulation of natural killer cell mediated immunity
G
Sh2d1b
SH2 domain containing 1B
ISO
13
86,096,465
86,126,881
RGD:1624291
RGD
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
G
Tlr4
toll-like receptor 4
ISO
5
83,564,100
83,577,735
RGD:1624291
RGD
G
Tlr4
toll-like receptor 4
IEA
5
83,564,100
83,577,735
RGD:1600115
ENSEMBL
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
G
Tlr4
toll-like receptor 4
ISO
5
83,564,100
83,577,735
RGD:1624291
RGD
G
Tlr4
toll-like receptor 4
IEA
5
83,564,100
83,577,735
RGD:1600115
ENSEMBL
positive regulation of respiratory burst involved in inflammatory response
G
Lbp
lipopolysaccharide binding protein
ISO
3
149,016,605
149,043,530
RGD:1624291
RGD
G
Lbp
lipopolysaccharide binding protein
IEA
3
149,016,605
149,043,530
RGD:1600115
ENSEMBL
G
Rps19
ribosomal protein S19
ISO
1
80,176,649
80,182,351
RGD:1624291
RGD
positive regulation of RIG-I signaling pathway
G
Ddx60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
ISO
16
30,934,840
31,080,644
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
ISO
10
89,630,145
89,641,311
RGD:1624291
RGD
G
Dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58
IEA
10
89,630,145
89,641,311
RGD:1600115
ENSEMBL
G
Zc3hav1
zinc finger CCCH type, antiviral 1
IEA
4
65,854,471
65,894,691
RGD:1600115
ENSEMBL
G
Zc3hav1
zinc finger CCCH type, antiviral 1
ISO
4
65,854,471
65,894,691
RGD:1624291
RGD
positive regulation of toll-like receptor 2 signaling pathway
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
ISO
2
25,886,177
25,899,128
RGD:1624291
RGD
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
IEA
2
25,886,177
25,899,128
RGD:1600115
ENSEMBL
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
positive regulation of toll-like receptor 3 signaling pathway
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
ISO
2
25,886,177
25,899,128
RGD:1624291
RGD
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
IEA
2
25,886,177
25,899,128
RGD:1600115
ENSEMBL
G
Peli1
pellino E3 ubiquitin protein ligase 1
ISO
14
101,870,272
101,924,228
RGD:1624291
RGD
G
Peli1
pellino E3 ubiquitin protein ligase 1
IEA
14
101,870,272
101,924,228
RGD:1600115
ENSEMBL
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
positive regulation of toll-like receptor 4 signaling pathway
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
ISO
2
25,886,177
25,899,128
RGD:1624291
RGD
G
F2rl1
coagulation factor II (thrombin) receptor-like 1
IEA
2
25,886,177
25,899,128
RGD:1600115
ENSEMBL
G
Lbp
lipopolysaccharide binding protein
ISO
3
149,016,605
149,043,530
RGD:1624291
RGD
G
Lbp
lipopolysaccharide binding protein
IEA
3
149,016,605
149,043,530
RGD:1600115
ENSEMBL
G
Nr1h3
nuclear receptor subfamily 1, group H, member 3
ISO
3
75,542,211
75,550,793
RGD:1624291
RGD
G
Nr1h3
nuclear receptor subfamily 1, group H, member 3
IEA
3
75,542,211
75,550,793
RGD:1600115
ENSEMBL
G
Peli1
pellino E3 ubiquitin protein ligase 1
ISO
14
101,870,272
101,924,228
RGD:1624291
RGD
G
Peli1
pellino E3 ubiquitin protein ligase 1
IEA
14
101,870,272
101,924,228
RGD:1600115
ENSEMBL
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
positive regulation of toll-like receptor 7 signaling pathway
G
Rsad2
radical S-adenosyl methionine domain containing 2
ISS
6
44,100,775
44,113,910
RGD:1600115
UniProtKB
G
Rsad2
radical S-adenosyl methionine domain containing 2
ISO
6
44,100,775
44,113,910
RGD:1624291
RGD
positive regulation of toll-like receptor 9 signaling pathway
G
Rsad2
radical S-adenosyl methionine domain containing 2
ISS
6
44,100,775
44,113,910
RGD:1600115
UniProtKB
G
Rsad2
radical S-adenosyl methionine domain containing 2
ISO
6
44,100,775
44,113,910
RGD:1624291
RGD
positive regulation of toll-like receptor signaling pathway
G
Tlr2
toll-like receptor 2
ISO
2
175,607,990
175,613,992
RGD:1624291
RGD
G
Tlr2
toll-like receptor 2
IEA
2
175,607,990
175,613,992
RGD:1600115
ENSEMBL
G
Tlr3
toll-like receptor 3
ISO
16
50,112,910
50,126,371
RGD:1624291
RGD
G
Tlr3
toll-like receptor 3
IEA
16
50,112,910
50,126,371
RGD:1600115
ENSEMBL
G
Tlr5
toll-like receptor 5
ISO
13
99,025,501
99,029,755
RGD:1624291
RGD
G
Tlr5
toll-like receptor 5
IEA
13
99,025,501
99,029,755
RGD:1600115
ENSEMBL
G
Tlr9
toll-like receptor 9
ISO
RGD:1624291
RGD
regulation of MyD88-dependent toll-like receptor signaling pathway
G
Irf1
interferon regulatory factor 1
ISO
10
39,220,600
39,227,602
RGD:1624291
RGD
G
Irf1
interferon regulatory factor 1
ISS
10
39,220,600
39,227,602
RGD:1600115
UniProtKB
G
Irf1
interferon regulatory factor 1
IEA
10
39,220,600
39,227,602
RGD:1600115
ENSEMBL
G
Irf7
interferon regulatory factor 7
ISO
1
201,456,689
201,459,756
RGD:1624291
RGD
G
Irf7
interferon regulatory factor 7
IEA
1
201,456,689
201,459,756
RGD:1600115
ENSEMBL
regulation of MyD88-independent toll-like receptor signaling pathway
G
Irf7
interferon regulatory factor 7
ISO
1
201,456,689
201,459,756
RGD:1624291
RGD
G
Irf7
interferon regulatory factor 7
IEA
1
201,456,689
201,459,756
RGD:1600115
ENSEMBL
regulation of toll-like receptor signaling pathway
G
Gfi1
growth factor independent 1 transcription repressor
ISO
14
2,597,303
2,606,681
RGD:1624291
RGD
G
Gfi1
growth factor independent 1 transcription repressor
IEA
14
2,597,303
2,606,681
RGD:1600115
ENSEMBL
RIG-I signaling pathway
G
Lsm14a
LSM14A, SCD6 homolog A (S. cerevisiae)
ISO
1
86,795,681
86,840,006
RGD:1624291
RGD
G
Mavs
mitochondrial antiviral signaling protein
ISO
3
118,938,433
118,953,081
RGD:1624291
RGD
stimulatory C-type lectin receptor signaling pathway
G
Klre1
killer cell lectin-like receptor, family E, member 1
ISO
4
166,857,685
166,864,221
RGD:1624291
RGD
G
Klre1
killer cell lectin-like receptor, family E, member 1
IEA
4
166,857,685
166,864,221
RGD:1600115
ENSEMBL
G
Klrk1
killer cell lectin-like receptor subfamily K, member 1
ISO
4
166,914,786
166,922,659
RGD:1624291
RGD
G
Klrk1
killer cell lectin-like receptor subfamily K, member 1
IEA
4
166,914,786
166,922,659
RGD:1600115
ENSEMBL
susceptibility to natural killer cell mediated cytotoxicity
G
Cadm1
cell adhesion molecule 1
ISO
8
50,765,645
51,108,962
RGD:1624291
RGD
G
Cadm1
cell adhesion molecule 1
ISO
8
50,765,645
51,108,962
RGD:1624291
RGD
G
Cadm1
cell adhesion molecule 1
ISS
8
50,765,645
51,108,962
RGD:1600115
UniProtKB
G
PVR
poliovirus receptor
ISO
1
79,213,654
79,229,063
RGD:1624291
RGD
G
Pvrl2
poliovirus receptor-related 2
ISO
1
79,021,831
79,059,686
RGD:1624291
RGD
G
Pvrl2
poliovirus receptor-related 2
IEA
1
79,021,831
79,059,686
RGD:1600115
ENSEMBL
TIRAP-dependent toll-like receptor 4 signaling pathway
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
toll-like receptor 10 signaling pathway
G
Tlr10
toll-like receptor 10
IEA
14
46,139,461
46,141,896
RGD:1600115
InterPro
toll-like receptor 11 signaling pathway
G
Tlr11
toll-like receptor 11
IEA
15
26,073,335
26,076,214
RGD:1600115
InterPro
toll-like receptor 12 signaling pathway
G
Tlr12
toll-like receptor 12
IEA
5
147,842,062
147,845,067
RGD:1600115
InterPro
toll-like receptor 13 signaling pathway
G
Tlr13
toll-like receptor 13
ISO
X
94,289,915
94,293,710
RGD:1624291
RGD
G
Tlr13
toll-like receptor 13
ISO
X
94,289,915
94,293,710
RGD:1624291
RGD
toll-like receptor 2 signaling pathway
G
Irak1
interleukin-1 receptor-associated kinase 1
ISO
X
159,960,184
159,969,180
RGD:1624291
RGD
G
Irak1
interleukin-1 receptor-associated kinase 1
ISO
X
159,960,184
159,969,180
RGD:1624291
RGD
G
Irak1
interleukin-1 receptor-associated kinase 1
IEA
X
159,960,184
159,969,180
RGD:1600115
ENSEMBL
G
Irak1
interleukin-1 receptor-associated kinase 1
IEA
X
159,960,184
159,969,180
RGD:1600115
ENSEMBL
G
Ripk2
receptor-interacting serine-threonine kinase 2
ISO
5
30,714,817
30,745,941
RGD:1624291
RGD
G
Ripk2
receptor-interacting serine-threonine kinase 2
IEA
5
30,714,817
30,745,941
RGD:1600115
ENSEMBL
G
Tlr2
toll-like receptor 2
IEA
2
175,607,990
175,613,992
RGD:1600115
InterPro
G
Tnip2
TNFAIP3 interacting protein 2
ISO
14
81,870,935
81,888,169
RGD:1624291
RGD
toll-like receptor 3 signaling pathway
G
Tlr3
toll-like receptor 3
IEA
16
50,112,910
50,126,371
RGD:1600115
InterPro
G
Tnip2
TNFAIP3 interacting protein 2
ISO
14
81,870,935
81,888,169
RGD:1624291
RGD
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
G
Unc93b1
unc-93 homolog B1 (C. elegans)
IEA
1
206,460,302
206,471,239
RGD:1600115
ENSEMBL
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
toll-like receptor 4 signaling pathway
G
Irak1
interleukin-1 receptor-associated kinase 1
ISO
X
159,960,184
159,969,180
RGD:1624291
RGD
G
Irak1
interleukin-1 receptor-associated kinase 1
IEA
X
159,960,184
159,969,180
RGD:1600115
ENSEMBL
G
LOC685385
similar to S100 calcium binding protein A14
IEA
2
182,800,173
182,809,448
RGD:1600115
ENSEMBL
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ISO
6
75,729,302
75,732,475
RGD:1624291
RGD
G
Nfkbia
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
IEA
6
75,729,302
75,732,475
RGD:1600115
ENSEMBL
G
Ripk2
receptor-interacting serine-threonine kinase 2
ISO
5
30,714,817
30,745,941
RGD:1624291
RGD
G
Ripk2
receptor-interacting serine-threonine kinase 2
IEA
5
30,714,817
30,745,941
RGD:1600115
ENSEMBL
G
Tlr4
toll-like receptor 4
IEA
5
83,564,100
83,577,735
RGD:1600115
InterPro
G
Tnip3
TNFAIP3 interacting protein 3
ISO
4
95,130,822
95,170,426
RGD:1624291
RGD
G
Tnip3
TNFAIP3 interacting protein 3
IEA
4
95,130,822
95,170,426
RGD:1600115
ENSEMBL
G
Tril
TLR4 interactor with leucine-rich repeats
ISO
4
82,177,050
82,181,895
RGD:1624291
RGD
toll-like receptor 5 signaling pathway
G
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
NOT
ISO
8
34,966,856
34,969,727
RGD:1624291
RGD
G
Tlr5
toll-like receptor 5
IEA
13
99,025,501
99,029,755
RGD:1600115
InterPro
toll-like receptor 6 signaling pathway
G
Tlr6
toll-like receptor 6
IEA
14
46,089,365
46,100,687
RGD:1600115
InterPro
toll-like receptor 7 signaling pathway
G
Tlr7
toll-like receptor 7
ISO
X
47,330,737
47,356,841
RGD:1624291
RGD
G
Tlr7
toll-like receptor 7
IEA
X
47,330,737
47,356,841
RGD:1600115
ENSEMBL
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
G
Unc93b1
unc-93 homolog B1 (C. elegans)
IEA
1
206,460,302
206,471,239
RGD:1600115
ENSEMBL
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
toll-like receptor 8 signaling pathway
G
Tlr8
toll-like receptor 8
IEA
RGD:1600115
InterPro
toll-like receptor 9 signaling pathway
G
Tlr9
toll-like receptor 9
IEA
RGD:1600115
InterPro
G
Tnip2
TNFAIP3 interacting protein 2
ISO
14
81,870,935
81,888,169
RGD:1624291
RGD
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
G
Unc93b1
unc-93 homolog B1 (C. elegans)
IEA
1
206,460,302
206,471,239
RGD:1600115
ENSEMBL
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
toll-like receptor signaling pathway
G
Cd86
CD86 molecule
ISO
11
66,215,233
66,238,882
RGD:1624291
RGD
G
Cd86
CD86 molecule
IEA
11
66,215,233
66,238,882
RGD:1600115
ENSEMBL
G
Mapkapk2
mitogen-activated protein kinase-activated protein kinase 2
ISO
13
43,994,943
44,041,504
RGD:1624291
RGD
G
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
ISO
8
112,497,626
112,531,778
RGD:1624291
RGD
G
Mapkapk3
mitogen-activated protein kinase-activated protein kinase 3
ISS
8
112,497,626
112,531,778
RGD:1600115
UniProtKB
G
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
ISO
X
56,722,878
56,825,444
RGD:1624291
RGD
G
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
IEA
X
56,722,878
56,825,444
RGD:1600115
ENSEMBL
G
Tlr1
toll-like receptor 1
IDA
RGD:1643119
RGD
G
Tlr2
toll-like receptor 2
IDA
2
175,607,990
175,613,992
RGD:1643119
RGD
G
Tlr2
toll-like receptor 2
IMP
2
175,607,990
175,613,992
RGD:5684896
RGD
G
Tlr3
toll-like receptor 3
IDA
16
50,112,910
50,126,371
RGD:1643119
RGD
G
Tlr4
toll-like receptor 4
IDA
5
83,564,100
83,577,735
RGD:1643119
RGD
G
Tlr6
toll-like receptor 6
IDA
14
46,089,365
46,100,687
RGD:1643119
RGD
G
Tlr6
toll-like receptor 6
IMP
14
46,089,365
46,100,687
RGD:5684896
RGD
G
Tlr7
toll-like receptor 7
IDA
X
47,330,737
47,356,841
RGD:1643119
RGD
G
Tlr8
toll-like receptor 8
IDA
RGD:1643119
RGD
G
Tlr9
toll-like receptor 9
IDA
RGD:1643119
RGD
G
Traf3
Tnf receptor-associated factor 3
ISO
6
135,925,375
136,027,270
RGD:1624291
RGD
G
Traf3
Tnf receptor-associated factor 3
IEA
6
135,925,375
136,027,270
RGD:1600115
ENSEMBL
G
Unc93b1
unc-93 homolog B1 (C. elegans)
ISO
1
206,460,302
206,471,239
RGD:1624291
RGD
TRAM-dependent toll-like receptor 4 signaling pathway
G
Prkce
protein kinase C, epsilon
ISO
6
9,631,234
10,097,311
RGD:1624291
RGD
G
Prkce
protein kinase C, epsilon
IEA
6
9,631,234
10,097,311
RGD:1600115
ENSEMBL
G
Prkce
protein kinase C, epsilon
ISS
6
9,631,234
10,097,311
RGD:1600115
UniProtKB
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest