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Term:pattern recognition receptor signaling pathway
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Accession:GO:0002221 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of binding to a cell surface or intracellular pattern recognition receptor (PRR). Such receptors bind for molecular patterns based on a repeating or polymeric structures, like those of polysaccharides or peptidoglycans, which are sometimes associated with potential pathogens.
Synonyms:exact_synonym: PAMP receptor signaling pathway;   PRR signaling pathway;   pathogen receptor signaling pathway;   pathogen receptor signalling pathway

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pattern recognition receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link ISO 4 13,471,878 13,525,620 RGD:1624291 RGD
G Clec7a C-type lectin domain family 7, member A GBrowse link ISO 4 166,723,515 166,734,681 RGD:1624291 RGD
G Colec12 collectin sub-family member 12 GBrowse link ISO 18 996,297 1,188,288 RGD:1624291 RGD
G Ptafr platelet-activating factor receptor GBrowse link ISO 5 152,565,687 152,587,342 RGD:1624291 RGD
G Trim5 tripartite motif-containing 5 GBrowse link ISO 1 162,096,439 162,113,409 RGD:1624291 RGD
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Clec7a C-type lectin domain family 7, member A GBrowse link ISO 4 166,723,515 166,734,681 RGD:1624291 RGD
G Tlr2 toll-like receptor 2 GBrowse link ISO 2 175,607,990 175,613,992 RGD:1624291 RGD
G Tlr2 toll-like receptor 2 GBrowse link IEA 2 175,607,990 175,613,992 RGD:1600115 ENSEMBL
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Hspd1 heat shock protein 1 (chaperonin) GBrowse link ISO 9 53,884,193 53,895,043 RGD:1624291 RGD
G Myd88 myeloid differentiation primary response 88 GBrowse link ISO 8 124,299,729 124,303,798 RGD:1624291 RGD
G Myd88 myeloid differentiation primary response 88 GBrowse link ISO 8 124,299,729 124,303,798 RGD:1624291 RGD
G Myd88 myeloid differentiation primary response 88 GBrowse link ISO 8 124,299,729 124,303,798 RGD:1624291 RGD
G Myd88 myeloid differentiation primary response 88 GBrowse link IEA 8 124,299,729 124,303,798 RGD:1600115 ENSEMBL
G Reg3g regenerating islet-derived 3 gamma GBrowse link ISS 4 112,418,258 112,420,813 RGD:1600115 UniProtKB
G Tlr10 toll-like receptor 10 GBrowse link IEA 14 46,139,461 46,141,896 RGD:1600115 InterPro
G Tlr11 toll-like receptor 11 GBrowse link IEA 15 26,073,335 26,076,214 RGD:1600115 InterPro
G Tlr13 toll-like receptor 13 GBrowse link ISO X 94,289,915 94,293,710 RGD:1624291 RGD
G Tlr2 toll-like receptor 2 GBrowse link ISO 2 175,607,990 175,613,992 RGD:1624291 RGD
G Tlr2 toll-like receptor 2 GBrowse link IEA 2 175,607,990 175,613,992 RGD:1600115 ENSEMBL
G Tlr4 toll-like receptor 4 GBrowse link IEA 5 83,564,100 83,577,735 RGD:1600115 InterPro
G Tlr5 toll-like receptor 5 GBrowse link IEA 13 99,025,501 99,029,755 RGD:1600115 InterPro
G Tlr6 toll-like receptor 6 GBrowse link IEA 14 46,089,365 46,100,687 RGD:1600115 InterPro
G Tlr7 toll-like receptor 7 GBrowse link IEA X 47,330,737 47,356,841 RGD:1600115 InterPro
G Tlr8 toll-like receptor 8 IEA RGD:1600115 InterPro
G Tlr9 toll-like receptor 9 IEA RGD:1600115 InterPro
G Tnip1 TNFAIP3 interacting protein 1 GBrowse link ISO 10 40,319,735 40,366,764 RGD:1624291 RGD
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr3 toll-like receptor 3 GBrowse link IEA 16 50,112,910 50,126,371 RGD:1600115 InterPro
G Tnip3 TNFAIP3 interacting protein 3 GBrowse link IEA 4 95,130,822 95,170,426 RGD:1600115 ENSEMBL
G Tnip3 TNFAIP3 interacting protein 3 GBrowse link ISO 4 95,130,822 95,170,426 RGD:1624291 RGD
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISS 10 57,881,783 57,886,434 RGD:1600115 UniProtKB
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISO 10 57,881,783 57,886,434 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link IEA 10 89,630,145 89,641,311 RGD:1600115 ENSEMBL
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISS 10 57,881,783 57,886,434 RGD:1600115 UniProtKB
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISO 10 57,881,783 57,886,434 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link IEA 10 89,630,145 89,641,311 RGD:1600115 ENSEMBL
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog GBrowse link ISO 5 16,933,111 17,054,564 RGD:1624291 RGD
G Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog GBrowse link ISS 5 16,933,111 17,054,564 RGD:1600115 UniProtKB
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link ISO 19 19,662,337 19,697,341 RGD:1624291 RGD
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link IEA 19 19,662,337 19,697,341 RGD:1600115 ENSEMBL
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link ISO 2 25,886,177 25,899,128 RGD:1624291 RGD
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link IEA 2 25,886,177 25,899,128 RGD:1600115 ENSEMBL
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Dab2ip DAB2 interacting protein GBrowse link ISO 3 14,667,700 14,840,625 RGD:1624291 RGD
G Dab2ip DAB2 interacting protein GBrowse link ISS 3 14,667,700 14,840,625 RGD:1600115 UniProtKB
G Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog GBrowse link ISO 5 16,933,111 17,054,564 RGD:1624291 RGD
G Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog GBrowse link ISS 5 16,933,111 17,054,564 RGD:1600115 UniProtKB
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 GBrowse link ISO 10 87,541,246 87,548,186 RGD:1624291 RGD
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 GBrowse link IEA 10 87,541,246 87,548,186 RGD:1600115 ENSEMBL
G Rab7b Rab7b, member RAS oncogene family GBrowse link IEA 13 44,620,063 44,636,864 RGD:1600115 ENSEMBL
G Ticam2 toll-like receptor adaptor molecule 2 GBrowse link ISO 18 40,776,776 40,793,784 RGD:1624291 RGD
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Rab7b Rab7b, member RAS oncogene family GBrowse link IEA 13 44,620,063 44,636,864 RGD:1600115 ENSEMBL
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Arrb2 arrestin, beta 2 GBrowse link ISO 10 57,244,071 57,284,166 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link IEA 10 57,244,071 57,284,166 RGD:1600115 ENSEMBL
G Cactin cactin, spliceosome C complex subunit GBrowse link ISO 7 9,875,757 9,880,563 RGD:1624291 RGD
G Irak3 interleukin-1 receptor-associated kinase 3 GBrowse link IEA 7 59,408,198 59,467,821 RGD:1600115 ENSEMBL
G Irak3 interleukin-1 receptor-associated kinase 3 GBrowse link ISO 7 59,408,198 59,467,821 RGD:1624291 RGD
G Irf4 interferon regulatory factor 4 GBrowse link ISO 17 40,170,409 40,189,976 RGD:1624291 RGD
G Irf4 interferon regulatory factor 4 GBrowse link IEA 17 40,170,409 40,189,976 RGD:1600115 ENSEMBL
G Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 GBrowse link ISO 20 3,629,246 3,644,222 RGD:1624291 RGD
G Nfkbil1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 GBrowse link ISS 20 3,629,246 3,644,222 RGD:1600115 UniProtKB
G Pdpk1 3-phosphoinositide dependent protein kinase-1 GBrowse link ISO 10 13,329,708 13,394,080 RGD:1624291 RGD
G Pdpk1 3-phosphoinositide dependent protein kinase-1 GBrowse link IEA 10 13,329,708 13,394,080 RGD:1600115 ENSEMBL
G Tlr9 toll-like receptor 9 ISO RGD:1624291 RGD
G Tyro3 TYRO3 protein tyrosine kinase GBrowse link ISO 3 106,309,671 106,328,607 RGD:1624291 RGD
G Tyro3 TYRO3 protein tyrosine kinase GBrowse link IEA 3 106,309,671 106,328,607 RGD:1600115 ENSEMBL
G Tyro3 TYRO3 protein tyrosine kinase GBrowse link ISS 3 106,309,671 106,328,607 RGD:1600115 UniProtKB
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link ISO 6 75,729,302 75,732,475 RGD:1624291 RGD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link IEA 6 75,729,302 75,732,475 RGD:1600115 ENSEMBL
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link ISO 6 75,729,302 75,732,475 RGD:1624291 RGD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link IEA 6 75,729,302 75,732,475 RGD:1600115 ENSEMBL
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link IEA 19 19,662,337 19,697,341 RGD:1600115 ENSEMBL
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link ISO 19 19,662,337 19,697,341 RGD:1624291 RGD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link ISO 1 208,262,669 208,273,148 RGD:1624291 RGD
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link IEA 1 208,262,669 208,273,148 RGD:1600115 ENSEMBL
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
positive regulation of MDA-5 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 GBrowse link ISO 16 30,934,840 31,080,644 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link IEA 10 89,630,145 89,641,311 RGD:1600115 ENSEMBL
positive regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Mog myelin oligodendrocyte glycoprotein GBrowse link IMP 20 1,601,731 1,611,963 BHF-UCL
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr4 toll-like receptor 4 GBrowse link ISO 5 83,564,100 83,577,735 RGD:1624291 RGD
G Tlr4 toll-like receptor 4 GBrowse link IEA 5 83,564,100 83,577,735 RGD:1600115 ENSEMBL
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr4 toll-like receptor 4 GBrowse link ISO 5 83,564,100 83,577,735 RGD:1624291 RGD
G Tlr4 toll-like receptor 4 GBrowse link IEA 5 83,564,100 83,577,735 RGD:1600115 ENSEMBL
positive regulation of RIG-I signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 GBrowse link ISO 16 30,934,840 31,080,644 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link ISO 10 89,630,145 89,641,311 RGD:1624291 RGD
G Dhx58 DEXH (Asp-Glu-X-His) box polypeptide 58 GBrowse link IEA 10 89,630,145 89,641,311 RGD:1600115 ENSEMBL
G Zc3hav1 zinc finger CCCH type, antiviral 1 GBrowse link IEA 4 65,854,471 65,894,691 RGD:1600115 ENSEMBL
G Zc3hav1 zinc finger CCCH type, antiviral 1 GBrowse link ISO 4 65,854,471 65,894,691 RGD:1624291 RGD
positive regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link ISO 2 25,886,177 25,899,128 RGD:1624291 RGD
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link IEA 2 25,886,177 25,899,128 RGD:1600115 ENSEMBL
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link ISO 8 34,966,856 34,969,727 RGD:1624291 RGD
positive regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link ISO 2 25,886,177 25,899,128 RGD:1624291 RGD
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link IEA 2 25,886,177 25,899,128 RGD:1600115 ENSEMBL
G Peli1 pellino E3 ubiquitin protein ligase 1 GBrowse link IEA 14 101,870,272 101,924,228 RGD:1600115 ENSEMBL
G Peli1 pellino E3 ubiquitin protein ligase 1 GBrowse link ISO 14 101,870,272 101,924,228 RGD:1624291 RGD
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link ISO 8 34,966,856 34,969,727 RGD:1624291 RGD
positive regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link ISO 2 25,886,177 25,899,128 RGD:1624291 RGD
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link IEA 2 25,886,177 25,899,128 RGD:1600115 ENSEMBL
G Lbp lipopolysaccharide binding protein GBrowse link ISO 3 149,016,605 149,043,530 RGD:1624291 RGD
G Lbp lipopolysaccharide binding protein GBrowse link IEA 3 149,016,605 149,043,530 RGD:1600115 ENSEMBL
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 GBrowse link ISO 3 75,542,211 75,550,793 RGD:1624291 RGD
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 GBrowse link IEA 3 75,542,211 75,550,793 RGD:1600115 ENSEMBL
G Peli1 pellino E3 ubiquitin protein ligase 1 GBrowse link IEA 14 101,870,272 101,924,228 RGD:1600115 ENSEMBL
G Peli1 pellino E3 ubiquitin protein ligase 1 GBrowse link ISO 14 101,870,272 101,924,228 RGD:1624291 RGD
G Ticam2 toll-like receptor adaptor molecule 2 GBrowse link ISO 18 40,776,776 40,793,784 RGD:1624291 RGD
G Ticam2 toll-like receptor adaptor molecule 2 GBrowse link ISO 18 40,776,776 40,793,784 RGD:1624291 RGD
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link ISO 8 34,966,856 34,969,727 RGD:1624291 RGD
positive regulation of toll-like receptor 7 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISS 6 44,100,775 44,113,910 RGD:1600115 UniProtKB
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISO 6 44,100,775 44,113,910 RGD:1624291 RGD
positive regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISS 6 44,100,775 44,113,910 RGD:1600115 UniProtKB
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISO 6 44,100,775 44,113,910 RGD:1624291 RGD
positive regulation of toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr2 toll-like receptor 2 GBrowse link ISO 2 175,607,990 175,613,992 RGD:1624291 RGD
G Tlr2 toll-like receptor 2 GBrowse link IEA 2 175,607,990 175,613,992 RGD:1600115 ENSEMBL
G Tlr3 toll-like receptor 3 GBrowse link ISO 16 50,112,910 50,126,371 RGD:1624291 RGD
G Tlr3 toll-like receptor 3 GBrowse link IEA 16 50,112,910 50,126,371 RGD:1600115 ENSEMBL
G Tlr5 toll-like receptor 5 GBrowse link ISO 13 99,025,501 99,029,755 RGD:1624291 RGD
G Tlr5 toll-like receptor 5 GBrowse link IEA 13 99,025,501 99,029,755 RGD:1600115 ENSEMBL
G Tlr9 toll-like receptor 9 ISO RGD:1624291 RGD
regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Irf1 interferon regulatory factor 1 GBrowse link ISO 10 39,220,600 39,227,602 RGD:1624291 RGD
G Irf1 interferon regulatory factor 1 GBrowse link ISS 10 39,220,600 39,227,602 RGD:1600115 UniProtKB
G Irf1 interferon regulatory factor 1 GBrowse link IEA 10 39,220,600 39,227,602 RGD:1600115 ENSEMBL
G Irf7 interferon regulatory factor 7 GBrowse link ISO 1 201,456,689 201,459,756 RGD:1624291 RGD
G Irf7 interferon regulatory factor 7 GBrowse link IEA 1 201,456,689 201,459,756 RGD:1600115 ENSEMBL
regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Irf7 interferon regulatory factor 7 GBrowse link ISO 1 201,456,689 201,459,756 RGD:1624291 RGD
G Irf7 interferon regulatory factor 7 GBrowse link IEA 1 201,456,689 201,459,756 RGD:1600115 ENSEMBL
regulation of toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Gfi1 growth factor independent 1 transcription repressor GBrowse link ISO 14 2,597,303 2,606,681 RGD:1624291 RGD
G Gfi1 growth factor independent 1 transcription repressor GBrowse link IEA 14 2,597,303 2,606,681 RGD:1600115 ENSEMBL
RIG-I signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Lsm14a LSM14A, SCD6 homolog A (S. cerevisiae) GBrowse link ISO 1 86,795,681 86,840,006 RGD:1624291 RGD
G Mavs mitochondrial antiviral signaling protein GBrowse link ISO 3 118,938,433 118,953,081 RGD:1624291 RGD
TIRAP-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link ISO 8 34,966,856 34,969,727 RGD:1624291 RGD
toll-like receptor 10 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr10 toll-like receptor 10 GBrowse link IEA 14 46,139,461 46,141,896 RGD:1600115 InterPro
toll-like receptor 11 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr11 toll-like receptor 11 GBrowse link IEA 15 26,073,335 26,076,214 RGD:1600115 InterPro
toll-like receptor 12 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr12 toll-like receptor 12 GBrowse link IEA 5 147,842,062 147,845,067 RGD:1600115 InterPro
toll-like receptor 13 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr13 toll-like receptor 13 GBrowse link ISO X 94,289,915 94,293,710 RGD:1624291 RGD
G Tlr13 toll-like receptor 13 GBrowse link ISO X 94,289,915 94,293,710 RGD:1624291 RGD
toll-like receptor 2 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link IEA X 159,960,184 159,969,180 RGD:1600115 ENSEMBL
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link IEA X 159,960,184 159,969,180 RGD:1600115 ENSEMBL
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link ISO X 159,960,184 159,969,180 RGD:1624291 RGD
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link ISO X 159,960,184 159,969,180 RGD:1624291 RGD
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
G Tlr2 toll-like receptor 2 GBrowse link IEA 2 175,607,990 175,613,992 RGD:1600115 InterPro
G Tnip2 TNFAIP3 interacting protein 2 GBrowse link ISO 14 81,870,935 81,888,169 RGD:1624291 RGD
toll-like receptor 3 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr3 toll-like receptor 3 GBrowse link IEA 16 50,112,910 50,126,371 RGD:1600115 InterPro
G Tnip2 TNFAIP3 interacting protein 2 GBrowse link ISO 14 81,870,935 81,888,169 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link IEA 1 206,460,302 206,471,239 RGD:1600115 ENSEMBL
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
toll-like receptor 4 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link IEA X 159,960,184 159,969,180 RGD:1600115 ENSEMBL
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link ISO X 159,960,184 159,969,180 RGD:1624291 RGD
G LOC685385 similar to S100 calcium binding protein A14 GBrowse link IEA 2 182,800,173 182,809,448 RGD:1600115 ENSEMBL
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link ISO 6 75,729,302 75,732,475 RGD:1624291 RGD
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha GBrowse link IEA 6 75,729,302 75,732,475 RGD:1600115 ENSEMBL
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
G Tlr4 toll-like receptor 4 GBrowse link IEA 5 83,564,100 83,577,735 RGD:1600115 InterPro
G Tnip3 TNFAIP3 interacting protein 3 GBrowse link IEA 4 95,130,822 95,170,426 RGD:1600115 ENSEMBL
G Tnip3 TNFAIP3 interacting protein 3 GBrowse link ISO 4 95,130,822 95,170,426 RGD:1624291 RGD
G Tril TLR4 interactor with leucine-rich repeats GBrowse link ISO 4 82,177,050 82,181,895 RGD:1624291 RGD
toll-like receptor 5 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link NOT ISO 8 34,966,856 34,969,727 RGD:1624291 RGD
G Tlr5 toll-like receptor 5 GBrowse link IEA 13 99,025,501 99,029,755 RGD:1600115 InterPro
toll-like receptor 6 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr6 toll-like receptor 6 GBrowse link IEA 14 46,089,365 46,100,687 RGD:1600115 InterPro
toll-like receptor 7 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Tlr7 toll-like receptor 7 GBrowse link IEA X 47,330,737 47,356,841 RGD:1600115 ENSEMBL
G Tlr7 toll-like receptor 7 GBrowse link ISO X 47,330,737 47,356,841 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link IEA 1 206,460,302 206,471,239 RGD:1600115 ENSEMBL
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
toll-like receptor 8 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Tlr8 toll-like receptor 8 IEA RGD:1600115 InterPro
toll-like receptor 9 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 ISO RGD:1624291 RGD
G Tlr9 toll-like receptor 9 IEA RGD:1600115 InterPro
G Tnip2 TNFAIP3 interacting protein 2 GBrowse link ISO 14 81,870,935 81,888,169 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link IEA 1 206,460,302 206,471,239 RGD:1600115 ENSEMBL
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
toll-like receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cd86 CD86 molecule GBrowse link ISO 11 66,215,233 66,238,882 RGD:1624291 RGD
G Cd86 CD86 molecule GBrowse link IEA 11 66,215,233 66,238,882 RGD:1600115 ENSEMBL
G Mapkapk2 mitogen-activated protein kinase-activated protein kinase 2 GBrowse link ISO 13 43,994,943 44,041,504 RGD:1624291 RGD
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 GBrowse link ISO 8 112,497,626 112,531,778 RGD:1624291 RGD
G Mapkapk3 mitogen-activated protein kinase-activated protein kinase 3 GBrowse link ISS 8 112,497,626 112,531,778 RGD:1600115 UniProtKB
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 GBrowse link IEA X 56,722,878 56,825,444 RGD:1600115 ENSEMBL
G Rps6ka3 ribosomal protein S6 kinase polypeptide 3 GBrowse link ISO X 56,722,878 56,825,444 RGD:1624291 RGD
G Tlr1 toll-like receptor 1 GBrowse link IDA 14 46,114,913 46,124,820 RGD:1643119 RGD
G Tlr2 toll-like receptor 2 GBrowse link IDA 2 175,607,990 175,613,992 RGD:1643119 RGD
G Tlr2 toll-like receptor 2 GBrowse link IMP 2 175,607,990 175,613,992 RGD:5684896 RGD
G Tlr3 toll-like receptor 3 GBrowse link IDA 16 50,112,910 50,126,371 RGD:1643119 RGD
G Tlr4 toll-like receptor 4 GBrowse link IDA 5 83,564,100 83,577,735 RGD:1643119 RGD
G Tlr6 toll-like receptor 6 GBrowse link IDA 14 46,089,365 46,100,687 RGD:1643119 RGD
G Tlr6 toll-like receptor 6 GBrowse link IMP 14 46,089,365 46,100,687 RGD:5684896 RGD
G Tlr7 toll-like receptor 7 GBrowse link IDA X 47,330,737 47,356,841 RGD:1643119 RGD
G Tlr8 toll-like receptor 8 IDA RGD:1643119 RGD
G Tlr9 toll-like receptor 9 IDA RGD:1643119 RGD
G Traf3 Tnf receptor-associated factor 3 GBrowse link IEA 6 135,925,375 136,027,270 RGD:1600115 ENSEMBL
G Traf3 Tnf receptor-associated factor 3 GBrowse link ISO 6 135,925,375 136,027,270 RGD:1624291 RGD
G Unc93b1 unc-93 homolog B1 (C. elegans) GBrowse link ISO 1 206,460,302 206,471,239 RGD:1624291 RGD
TRAM-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Prkce protein kinase C, epsilon GBrowse link ISO 6 9,631,234 10,097,311 RGD:1624291 RGD
G Prkce protein kinase C, epsilon GBrowse link IEA 6 9,631,234 10,097,311 RGD:1600115 ENSEMBL
G Prkce protein kinase C, epsilon GBrowse link ISS 6 9,631,234 10,097,311 RGD:1600115 UniProtKB
G Ticam2 toll-like receptor adaptor molecule 2 GBrowse link ISO 18 40,776,776 40,793,784 RGD:1624291 RGD
G Ticam2 toll-like receptor adaptor molecule 2 GBrowse link ISO 18 40,776,776 40,793,784 RGD:1624291 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 136531
    immune system process 6166
      activation of immune response 520
        immune response-activating signal transduction 411
          innate immune response-activating signal transduction 217
            pattern recognition receptor signaling pathway 210
              cell surface pattern recognition receptor signaling pathway 3
              cytoplasmic pattern recognition receptor signaling pathway + 36
              intracellular vesicle pattern recognition receptor signaling pathway 0
              toll-like receptor signaling pathway + 166
Path 2
Term Annotations click to browse term
  biological_process 136531
    biological regulation 56771
      regulation of biological process 51779
        regulation of response to stimulus 7798
          regulation of response to stress 1634
            regulation of defense response 811
              regulation of innate immune response 395
                positive regulation of innate immune response 317
                  activation of innate immune response 236
                    innate immune response-activating signal transduction 217
                      pattern recognition receptor signaling pathway 210
                        cell surface pattern recognition receptor signaling pathway 3
                        cytoplasmic pattern recognition receptor signaling pathway + 36
                        intracellular vesicle pattern recognition receptor signaling pathway 0
                        toll-like receptor signaling pathway + 166
paths to the root

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