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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T cell mediated immunity
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Accession:GO:0002710 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.
Synonyms:exact_synonym: down regulation of T cell mediated immunity;   downregulation of T cell mediated immunity;   negative regulation of T lymphocyte mediated immunity
 narrow_synonym: inhibition of T cell mediated immunity


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negative regulation of T cell mediated immunity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd80 Cd80 molecule involved_in ISO (PMID:11015443) RGD PMID:11015443 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO MGI:5510586 (PMID:19632227), (PMID:23487419) RGD PMID:19632227 PMID:23487419 NCBI chr12:1,780,370...1,785,027
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (PMID:24714587) RGD PMID:24714587 NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:16949315) RGD PMID:16949315 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:18424730)
GO_REF:0000024		 RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO (PMID:32647003) RGD PMID:32647003 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
negative regulation of T cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 involved_in ISO (PMID:15466453), (PMID:23169781) RGD PMID:15466453 PMID:23169781 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:5700313|PMID:11477403) RGD PMID:11477403 MGI:5700313 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5634593|PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 MGI:5634593 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Vsir V-set immunoregulatory receptor acts_upstream_of_or_within ISO (PMID:21383057) RGD PMID:21383057 NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T cell mediated cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS		 (PMID:18424730)
GO_REF:0000024		 RGD
UniProt		 PMID:18424730 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:9215624) RGD PMID:9215624 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Klrc1 killer cell lectin like receptor C1 involved_in ISO (PMID:9485206) RGD PMID:9485206 NCBI chr 4:163,142,142...163,152,425
Ensembl chr 4:163,147,189...163,152,425 		JBrowse link
G Klrd1 killer cell lectin like receptor D1 involved_in ISO
IEA
ISS		 (PMID:9485206)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9485206 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:163,044,920...163,056,568
Ensembl chr 4:163,045,067...163,056,518 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2181294 (PMID:18097009)		 Ensembl
RGD		 PMID:18097009 GO_REF:0000107 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3654612|PMID:9725213)		 UniProt
RGD		 PMID:9725213 GO_REF:0000024 MGI:3654612 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:11290782) RGD PMID:11290782 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS
IEA		 (PMID:32818467)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:32818467 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(MGI:6508501|PMID:21469114), (MGI:6508513|PMID:28405502)		 RGD PMID:21469114 PMID:28405502 PMID:32818467 MGI:6508501 MGI:6508513 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
ISS		 (PMID:38377992)
GO_REF:0000024		 RGD
UniProt		 PMID:38377992 GO_REF:0000024 NCBI chr 5:38,962,721...38,995,134
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
negative regulation of T-helper 2 cell cytokine production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (MGI:5908339|PMID:19360123)
GO_REF:0000107		 RGD
Ensembl		 PMID:19360123 GO_REF:0000107 MGI:5908339 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO (MGI:1354779|PMID:10761931), (MGI:5543347|PMID:23616576) RGD PMID:10761931 PMID:23616576 MGI:1354779 MGI:5543347 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
negative regulation of type IV hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO MGI:3830304 (PMID:19124723) RGD PMID:19124723 NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:9645617) RGD PMID:9645617 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    immune system process 3017
      immune effector process 838
        leukocyte mediated immunity 588
          lymphocyte mediated immunity 471
            T cell mediated immunity 167
              negative regulation of T cell mediated immunity 31
                negative regulation of T cell antigen processing and presentation 0
                negative regulation of T cell cytokine production + 11
                negative regulation of T cell mediated cytotoxicity + 9
                negative regulation of T cell mediated immune response to tumor cell + 6
                negative regulation of peripheral T cell tolerance induction + 0
                negative regulation of type IV hypersensitivity 2
Path 2
Term Annotations click to browse term
  biological_process 20413
    biological regulation 13755
      regulation of biological process 13322
        regulation of immune system process 1705
          negative regulation of immune system process 567
            negative regulation of immune effector process 143
              negative regulation of leukocyte mediated immunity 80
                negative regulation of lymphocyte mediated immunity 67
                  negative regulation of T cell mediated immunity 31
                    negative regulation of T cell antigen processing and presentation 0
                    negative regulation of T cell cytokine production + 11
                    negative regulation of T cell mediated cytotoxicity + 9
                    negative regulation of T cell mediated immune response to tumor cell + 6
                    negative regulation of peripheral T cell tolerance induction + 0
                    negative regulation of type IV hypersensitivity 2
paths to the root