Gene: Nod2 (nucleotide-binding oligomerization domain containing 2) Rattus norvegicus
Symbol: Nod2
Name: nucleotide-binding oligomerization domain containing 2
Description: ENCODES a protein that exhibits muramyl dipeptide binding; CARD domain binding (ortholog); enzyme binding (ortholog); INVOLVED IN cellular response to organic cyclic compound; positive regulation of cell proliferation; positive regulation of dendritic cell cytokine production; PARTICIPATES IN NOD-like receptor signaling pathway; nuclear factor kappa B signaling pathway; Mycobacterium tuberculosis infection pathway; ASSOCIATED WITH Acute Lung Injury; Colitis; Pancreatitis; FOUND IN cytoplasm; cell surface (ortholog); COP9 signalosome (ortholog); INTERACTS WITH 2,4,6-trinitrobenzenesulfonic acid; bisphenol A; troglitazone
Type: protein-coding
Also known as: Card15; caspase recruitment domain family, member 15; LOC291912; nucleotide-binding oligomerization domain-containing protein 2
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01919,342,061 - 19,389,365-NCBI
Rat Cytogenetic Map19p11 NCBI
RGSC Genome Assembly v5.01930,375,065 - 30,409,527-NCBI
RGSC Genome Assembly v3.41919,662,337 - 19,697,341-NCBI
Rat Celera Assembly1918,269,940 - 18,304,004-NCBI
Genome Assembly 3.11919,670,606 - 19,715,845-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Nod2
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1306368
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE